| Full name: serine/threonine kinase 33 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 65975 | HGNC ID: HGNC:14568 | Ensembl Gene: ENSG00000130413 | OMIM ID: 607670 |
| Drug and gene relationship at DGIdb | |||
Expression of STK33:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STK33 | 65975 | 228035_at | -0.3551 | 0.4392 | |
| GSE26886 | STK33 | 65975 | 228035_at | 0.3225 | 0.0921 | |
| GSE45670 | STK33 | 65975 | 228035_at | -0.1051 | 0.5392 | |
| GSE53622 | STK33 | 65975 | 63311 | -0.8689 | 0.0000 | |
| GSE53624 | STK33 | 65975 | 63311 | -0.4335 | 0.0063 | |
| GSE63941 | STK33 | 65975 | 228035_at | -0.3806 | 0.2993 | |
| GSE77861 | STK33 | 65975 | 228035_at | -0.0733 | 0.5657 | |
| GSE97050 | STK33 | 65975 | A_23_P127915 | -0.3293 | 0.4662 | |
| SRP064894 | STK33 | 65975 | RNAseq | -0.2202 | 0.5783 | |
| SRP133303 | STK33 | 65975 | RNAseq | -0.3042 | 0.4677 | |
| SRP159526 | STK33 | 65975 | RNAseq | 0.4870 | 0.3068 | |
| SRP219564 | STK33 | 65975 | RNAseq | -0.4105 | 0.6962 | |
| TCGA | STK33 | 65975 | RNAseq | -1.1924 | 0.0027 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by STK33 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STK33:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STK33 | 65975 | 0 | 10 | 20 | |
| GSE20123 | STK33 | 65975 | 0 | 10 | 20 | |
| GSE43470 | STK33 | 65975 | 2 | 6 | 35 | |
| GSE46452 | STK33 | 65975 | 7 | 5 | 47 | |
| GSE47630 | STK33 | 65975 | 2 | 12 | 26 | |
| GSE54993 | STK33 | 65975 | 3 | 1 | 66 | |
| GSE54994 | STK33 | 65975 | 2 | 12 | 39 | |
| GSE60625 | STK33 | 65975 | 0 | 0 | 11 | |
| GSE74703 | STK33 | 65975 | 1 | 5 | 30 | |
| GSE74704 | STK33 | 65975 | 0 | 8 | 12 | |
| TCGA | STK33 | 65975 | 10 | 35 | 51 |
Total number of gains: 27; Total number of losses: 104; Total Number of normals: 357.
Somatic mutations of STK33:
Generating mutation plots.
Highly correlated genes for STK33:
Showing top 20/328 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STK33 | KATNAL1 | 0.761896 | 3 | 0 | 3 |
| STK33 | WSCD2 | 0.739066 | 3 | 0 | 3 |
| STK33 | ZER1 | 0.736449 | 3 | 0 | 3 |
| STK33 | IQUB | 0.73587 | 3 | 0 | 3 |
| STK33 | CNGA3 | 0.733005 | 4 | 0 | 3 |
| STK33 | ADD1 | 0.731265 | 3 | 0 | 3 |
| STK33 | BTC | 0.717021 | 3 | 0 | 3 |
| STK33 | DACT3 | 0.715938 | 5 | 0 | 4 |
| STK33 | MYEF2 | 0.708722 | 4 | 0 | 4 |
| STK33 | RYR3 | 0.704992 | 4 | 0 | 4 |
| STK33 | MYOM1 | 0.704616 | 4 | 0 | 3 |
| STK33 | TECPR2 | 0.702013 | 3 | 0 | 3 |
| STK33 | HSPB3 | 0.701808 | 3 | 0 | 3 |
| STK33 | ADCYAP1R1 | 0.698638 | 3 | 0 | 3 |
| STK33 | HS6ST3 | 0.696642 | 4 | 0 | 3 |
| STK33 | POU6F1 | 0.693433 | 3 | 0 | 3 |
| STK33 | ADCY5 | 0.68925 | 4 | 0 | 3 |
| STK33 | PYROXD2 | 0.686446 | 3 | 0 | 3 |
| STK33 | SLC8A1 | 0.685473 | 4 | 0 | 3 |
| STK33 | SOD3 | 0.679806 | 4 | 0 | 4 |
For details and further investigation, click here
