| Full name: heat shock factor binding protein 1 like 1 | Alias Symbol: FLJ10967|MGC189743 | ||
| Type: protein-coding gene | Cytoband: 18q23 | ||
| Entrez ID: 440498 | HGNC ID: HGNC:37243 | Ensembl Gene: ENSG00000226742 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of HSBP1L1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HSBP1L1 | 440498 | 232594_at | -0.8248 | 0.2746 | |
| GSE26886 | HSBP1L1 | 440498 | 232594_at | -0.9633 | 0.0000 | |
| GSE45670 | HSBP1L1 | 440498 | 232594_at | -0.3874 | 0.0770 | |
| GSE53622 | HSBP1L1 | 440498 | 130007 | -0.7611 | 0.0000 | |
| GSE53624 | HSBP1L1 | 440498 | 130007 | -1.0911 | 0.0000 | |
| GSE63941 | HSBP1L1 | 440498 | 232594_at | -0.3578 | 0.4820 | |
| GSE77861 | HSBP1L1 | 440498 | 232594_at | -0.6901 | 0.0451 | |
| GSE97050 | HSBP1L1 | 440498 | A_32_P46981 | -0.2035 | 0.5916 | |
| SRP007169 | HSBP1L1 | 440498 | RNAseq | -3.7049 | 0.0000 | |
| SRP008496 | HSBP1L1 | 440498 | RNAseq | -2.9993 | 0.0000 | |
| SRP064894 | HSBP1L1 | 440498 | RNAseq | -1.0477 | 0.0001 | |
| SRP133303 | HSBP1L1 | 440498 | RNAseq | -0.9513 | 0.0000 | |
| SRP159526 | HSBP1L1 | 440498 | RNAseq | -1.5405 | 0.0000 | |
| SRP193095 | HSBP1L1 | 440498 | RNAseq | -1.1957 | 0.0000 | |
| SRP219564 | HSBP1L1 | 440498 | RNAseq | -1.5157 | 0.0147 | |
| TCGA | HSBP1L1 | 440498 | RNAseq | -0.1684 | 0.1281 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by HSBP1L1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HSBP1L1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HSBP1L1 | 440498 | 1 | 12 | 17 | |
| GSE20123 | HSBP1L1 | 440498 | 1 | 12 | 17 | |
| GSE43470 | HSBP1L1 | 440498 | 0 | 12 | 31 | |
| GSE46452 | HSBP1L1 | 440498 | 1 | 26 | 32 | |
| GSE47630 | HSBP1L1 | 440498 | 5 | 22 | 13 | |
| GSE54993 | HSBP1L1 | 440498 | 9 | 0 | 61 | |
| GSE54994 | HSBP1L1 | 440498 | 1 | 19 | 33 | |
| GSE60625 | HSBP1L1 | 440498 | 0 | 4 | 7 | |
| GSE74703 | HSBP1L1 | 440498 | 0 | 8 | 28 | |
| GSE74704 | HSBP1L1 | 440498 | 0 | 9 | 11 | |
| TCGA | HSBP1L1 | 440498 | 7 | 45 | 44 |
Total number of gains: 25; Total number of losses: 169; Total Number of normals: 294.
Somatic mutations of HSBP1L1:
Generating mutation plots.
Highly correlated genes for HSBP1L1:
Showing top 20/1238 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HSBP1L1 | ATP6V1C2 | 0.752792 | 4 | 0 | 4 |
| HSBP1L1 | DHRS9 | 0.748596 | 4 | 0 | 4 |
| HSBP1L1 | SPINK7 | 0.746167 | 6 | 0 | 6 |
| HSBP1L1 | CASP1 | 0.741542 | 3 | 0 | 3 |
| HSBP1L1 | NMU | 0.740088 | 6 | 0 | 6 |
| HSBP1L1 | KIF21A | 0.738724 | 4 | 0 | 4 |
| HSBP1L1 | ULK3 | 0.734495 | 7 | 0 | 7 |
| HSBP1L1 | SCEL | 0.733416 | 6 | 0 | 6 |
| HSBP1L1 | ANXA9 | 0.733025 | 7 | 0 | 7 |
| HSBP1L1 | ECM1 | 0.732292 | 6 | 0 | 6 |
| HSBP1L1 | ATG9B | 0.731795 | 7 | 0 | 7 |
| HSBP1L1 | GMDS | 0.729564 | 6 | 0 | 6 |
| HSBP1L1 | FUT3 | 0.727985 | 6 | 0 | 6 |
| HSBP1L1 | ZDHHC13 | 0.727382 | 7 | 0 | 7 |
| HSBP1L1 | RUFY3 | 0.724584 | 4 | 0 | 4 |
| HSBP1L1 | YOD1 | 0.721208 | 7 | 0 | 6 |
| HSBP1L1 | CYSRT1 | 0.720923 | 6 | 0 | 6 |
| HSBP1L1 | EHD3 | 0.720823 | 7 | 0 | 7 |
| HSBP1L1 | PRSS2 | 0.720455 | 4 | 0 | 4 |
| HSBP1L1 | C12orf29 | 0.719322 | 6 | 0 | 6 |
For details and further investigation, click here
