| Full name: heat shock transcription factor 2 binding protein | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 21q22.3 | ||
| Entrez ID: 11077 | HGNC ID: HGNC:5226 | Ensembl Gene: ENSG00000160207 | OMIM ID: 604554 |
| Drug and gene relationship at DGIdb | |||
Expression of HSF2BP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HSF2BP | 11077 | 207020_at | 0.2554 | 0.3851 | |
| GSE20347 | HSF2BP | 11077 | 207020_at | 0.2369 | 0.0110 | |
| GSE23400 | HSF2BP | 11077 | 207020_at | 0.0117 | 0.8435 | |
| GSE26886 | HSF2BP | 11077 | 207020_at | 0.5716 | 0.0004 | |
| GSE29001 | HSF2BP | 11077 | 207020_at | 0.2842 | 0.2300 | |
| GSE38129 | HSF2BP | 11077 | 207020_at | 0.2219 | 0.0139 | |
| GSE45670 | HSF2BP | 11077 | 207020_at | 0.4759 | 0.0710 | |
| GSE53622 | HSF2BP | 11077 | 76502 | 0.6086 | 0.0000 | |
| GSE53624 | HSF2BP | 11077 | 76502 | 0.7948 | 0.0000 | |
| GSE63941 | HSF2BP | 11077 | 207020_at | 0.4096 | 0.4766 | |
| GSE77861 | HSF2BP | 11077 | 207020_at | -0.0945 | 0.5412 | |
| GSE97050 | HSF2BP | 11077 | A_23_P143512 | 0.0437 | 0.8312 | |
| SRP133303 | HSF2BP | 11077 | RNAseq | 1.3412 | 0.0002 | |
| SRP159526 | HSF2BP | 11077 | RNAseq | 1.5428 | 0.0060 | |
| SRP219564 | HSF2BP | 11077 | RNAseq | 1.1964 | 0.0751 | |
| TCGA | HSF2BP | 11077 | RNAseq | 1.3828 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by HSF2BP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HSF2BP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HSF2BP | 11077 | 2 | 8 | 20 | |
| GSE20123 | HSF2BP | 11077 | 2 | 8 | 20 | |
| GSE43470 | HSF2BP | 11077 | 0 | 13 | 30 | |
| GSE46452 | HSF2BP | 11077 | 1 | 21 | 37 | |
| GSE47630 | HSF2BP | 11077 | 6 | 17 | 17 | |
| GSE54993 | HSF2BP | 11077 | 8 | 1 | 61 | |
| GSE54994 | HSF2BP | 11077 | 4 | 8 | 41 | |
| GSE60625 | HSF2BP | 11077 | 0 | 0 | 11 | |
| GSE74703 | HSF2BP | 11077 | 0 | 10 | 26 | |
| GSE74704 | HSF2BP | 11077 | 1 | 4 | 15 | |
| TCGA | HSF2BP | 11077 | 7 | 40 | 49 |
Total number of gains: 31; Total number of losses: 130; Total Number of normals: 327.
Somatic mutations of HSF2BP:
Generating mutation plots.
Highly correlated genes for HSF2BP:
Showing top 20/188 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HSF2BP | LAMA5 | 0.774152 | 3 | 0 | 3 |
| HSF2BP | TNFAIP8L1 | 0.755814 | 3 | 0 | 3 |
| HSF2BP | ZNF511 | 0.743515 | 4 | 0 | 3 |
| HSF2BP | CA6 | 0.728376 | 3 | 0 | 3 |
| HSF2BP | RASGEF1A | 0.692435 | 3 | 0 | 3 |
| HSF2BP | NR2E1 | 0.667041 | 6 | 0 | 4 |
| HSF2BP | CACNA1I | 0.663549 | 3 | 0 | 3 |
| HSF2BP | BMP10 | 0.661826 | 4 | 0 | 3 |
| HSF2BP | NRG4 | 0.653721 | 3 | 0 | 3 |
| HSF2BP | HOXC9 | 0.64444 | 4 | 0 | 3 |
| HSF2BP | ZNF526 | 0.643149 | 5 | 0 | 4 |
| HSF2BP | FCAMR | 0.641628 | 3 | 0 | 3 |
| HSF2BP | ZBTB48 | 0.638405 | 4 | 0 | 3 |
| HSF2BP | PHF1 | 0.63544 | 4 | 0 | 3 |
| HSF2BP | ZNF205 | 0.632481 | 4 | 0 | 3 |
| HSF2BP | MAK | 0.630039 | 4 | 0 | 4 |
| HSF2BP | NSUN6 | 0.629042 | 3 | 0 | 3 |
| HSF2BP | RIMS4 | 0.62866 | 3 | 0 | 3 |
| HSF2BP | SDCCAG8 | 0.62708 | 4 | 0 | 3 |
| HSF2BP | OBSL1 | 0.625439 | 4 | 0 | 4 |
For details and further investigation, click here
