| Full name: SRY-box transcription factor 15 | Alias Symbol: SOX27|SOX26 | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 6665 | HGNC ID: HGNC:11196 | Ensembl Gene: ENSG00000129194 | OMIM ID: 601297 |
| Drug and gene relationship at DGIdb | |||
Expression of SOX15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SOX15 | 6665 | 206122_at | -0.2234 | 0.7748 | |
| GSE20347 | SOX15 | 6665 | 206122_at | -0.0757 | 0.7628 | |
| GSE23400 | SOX15 | 6665 | 206122_at | 0.1164 | 0.2443 | |
| GSE26886 | SOX15 | 6665 | 206122_at | -0.0085 | 0.9827 | |
| GSE29001 | SOX15 | 6665 | 206122_at | -0.2831 | 0.5388 | |
| GSE38129 | SOX15 | 6665 | 206122_at | 0.2281 | 0.3862 | |
| GSE45670 | SOX15 | 6665 | 206122_at | 0.2869 | 0.1195 | |
| GSE53622 | SOX15 | 6665 | 26797 | -0.0877 | 0.3027 | |
| GSE53624 | SOX15 | 6665 | 26797 | -0.2223 | 0.0135 | |
| GSE63941 | SOX15 | 6665 | 206122_at | 2.4750 | 0.0174 | |
| GSE77861 | SOX15 | 6665 | 206122_at | 0.1736 | 0.4985 | |
| GSE97050 | SOX15 | 6665 | A_23_P164011 | 1.6749 | 0.2641 | |
| SRP007169 | SOX15 | 6665 | RNAseq | -0.6143 | 0.2388 | |
| SRP008496 | SOX15 | 6665 | RNAseq | -0.6722 | 0.0366 | |
| SRP064894 | SOX15 | 6665 | RNAseq | -0.4482 | 0.1643 | |
| SRP133303 | SOX15 | 6665 | RNAseq | -0.2042 | 0.5316 | |
| SRP159526 | SOX15 | 6665 | RNAseq | -0.1229 | 0.8139 | |
| SRP219564 | SOX15 | 6665 | RNAseq | -0.3719 | 0.5542 | |
| TCGA | SOX15 | 6665 | RNAseq | 1.1412 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by SOX15 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SOX15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SOX15 | 6665 | 4 | 2 | 24 | |
| GSE20123 | SOX15 | 6665 | 4 | 3 | 23 | |
| GSE43470 | SOX15 | 6665 | 1 | 5 | 37 | |
| GSE46452 | SOX15 | 6665 | 34 | 1 | 24 | |
| GSE47630 | SOX15 | 6665 | 7 | 1 | 32 | |
| GSE54993 | SOX15 | 6665 | 4 | 3 | 63 | |
| GSE54994 | SOX15 | 6665 | 5 | 8 | 40 | |
| GSE60625 | SOX15 | 6665 | 4 | 0 | 7 | |
| GSE74703 | SOX15 | 6665 | 1 | 2 | 33 | |
| GSE74704 | SOX15 | 6665 | 2 | 1 | 17 | |
| TCGA | SOX15 | 6665 | 17 | 21 | 58 |
Total number of gains: 83; Total number of losses: 47; Total Number of normals: 358.
Somatic mutations of SOX15:
Generating mutation plots.
Highly correlated genes for SOX15:
Showing top 20/225 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SOX15 | CLDN9 | 0.716904 | 3 | 0 | 3 |
| SOX15 | STAP2 | 0.704092 | 3 | 0 | 3 |
| SOX15 | FAM153A | 0.694118 | 3 | 0 | 3 |
| SOX15 | CPNE6 | 0.681997 | 3 | 0 | 3 |
| SOX15 | C17orf53 | 0.680512 | 4 | 0 | 3 |
| SOX15 | HYAL4 | 0.678493 | 3 | 0 | 3 |
| SOX15 | SPHK1 | 0.658885 | 4 | 0 | 4 |
| SOX15 | PRKCSH | 0.656529 | 3 | 0 | 3 |
| SOX15 | MYO19 | 0.651696 | 6 | 0 | 6 |
| SOX15 | KLHL25 | 0.642365 | 3 | 0 | 3 |
| SOX15 | ART1 | 0.640778 | 3 | 0 | 3 |
| SOX15 | INCENP | 0.640217 | 3 | 0 | 3 |
| SOX15 | ANO9 | 0.638621 | 4 | 0 | 3 |
| SOX15 | DRD4 | 0.631395 | 3 | 0 | 3 |
| SOX15 | PSRC1 | 0.627322 | 3 | 0 | 3 |
| SOX15 | LPCAT2 | 0.623882 | 3 | 0 | 3 |
| SOX15 | KRTAP5-9 | 0.623716 | 3 | 0 | 3 |
| SOX15 | MYBPC3 | 0.615989 | 4 | 0 | 3 |
| SOX15 | CDH3 | 0.614447 | 5 | 0 | 3 |
| SOX15 | F11R | 0.614351 | 5 | 0 | 4 |
For details and further investigation, click here
