| Full name: complement C1r subcomponent like | Alias Symbol: C1r-LP|C1RL1 | ||
| Type: protein-coding gene | Cytoband: 12p13.31 | ||
| Entrez ID: 51279 | HGNC ID: HGNC:21265 | Ensembl Gene: ENSG00000139178 | OMIM ID: 608974 |
| Drug and gene relationship at DGIdb | |||
Expression of C1RL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C1RL | 51279 | 218983_at | -0.3119 | 0.5095 | |
| GSE20347 | C1RL | 51279 | 218983_at | 0.5405 | 0.0278 | |
| GSE23400 | C1RL | 51279 | 218983_at | 0.3371 | 0.0000 | |
| GSE26886 | C1RL | 51279 | 233645_s_at | 0.1480 | 0.2092 | |
| GSE29001 | C1RL | 51279 | 218983_at | 0.7987 | 0.0186 | |
| GSE38129 | C1RL | 51279 | 218983_at | 0.2803 | 0.3335 | |
| GSE45670 | C1RL | 51279 | 218983_at | 0.0318 | 0.9262 | |
| GSE53622 | C1RL | 51279 | 89561 | 0.5177 | 0.0000 | |
| GSE53624 | C1RL | 51279 | 89561 | 0.4924 | 0.0000 | |
| GSE63941 | C1RL | 51279 | 218983_at | -2.3073 | 0.0031 | |
| GSE77861 | C1RL | 51279 | 233645_s_at | 0.0065 | 0.9609 | |
| GSE97050 | C1RL | 51279 | A_23_P363968 | 0.2746 | 0.2830 | |
| SRP007169 | C1RL | 51279 | RNAseq | 1.4694 | 0.0001 | |
| SRP008496 | C1RL | 51279 | RNAseq | 1.6817 | 0.0002 | |
| SRP064894 | C1RL | 51279 | RNAseq | 0.8443 | 0.0000 | |
| SRP133303 | C1RL | 51279 | RNAseq | 0.4637 | 0.1207 | |
| SRP159526 | C1RL | 51279 | RNAseq | 0.3995 | 0.0626 | |
| SRP193095 | C1RL | 51279 | RNAseq | 0.7974 | 0.0000 | |
| SRP219564 | C1RL | 51279 | RNAseq | 0.7728 | 0.0995 | |
| TCGA | C1RL | 51279 | RNAseq | -0.0363 | 0.5622 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by C1RL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C1RL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C1RL | 51279 | 7 | 3 | 20 | |
| GSE20123 | C1RL | 51279 | 7 | 3 | 20 | |
| GSE43470 | C1RL | 51279 | 8 | 3 | 32 | |
| GSE46452 | C1RL | 51279 | 10 | 1 | 48 | |
| GSE47630 | C1RL | 51279 | 12 | 2 | 26 | |
| GSE54993 | C1RL | 51279 | 1 | 10 | 59 | |
| GSE54994 | C1RL | 51279 | 10 | 2 | 41 | |
| GSE60625 | C1RL | 51279 | 0 | 1 | 10 | |
| GSE74703 | C1RL | 51279 | 7 | 2 | 27 | |
| GSE74704 | C1RL | 51279 | 4 | 2 | 14 | |
| TCGA | C1RL | 51279 | 40 | 6 | 50 |
Total number of gains: 106; Total number of losses: 35; Total Number of normals: 347.
Somatic mutations of C1RL:
Generating mutation plots.
Highly correlated genes for C1RL:
Showing top 20/539 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C1RL | IFI27L2 | 0.800553 | 3 | 0 | 3 |
| C1RL | CLU | 0.73283 | 3 | 0 | 3 |
| C1RL | FCGR3A | 0.72837 | 3 | 0 | 3 |
| C1RL | FGF1 | 0.727956 | 3 | 0 | 3 |
| C1RL | GNG10 | 0.727496 | 3 | 0 | 3 |
| C1RL | KLF13 | 0.718284 | 3 | 0 | 3 |
| C1RL | STARD3NL | 0.713878 | 3 | 0 | 3 |
| C1RL | CLEC1A | 0.710205 | 3 | 0 | 3 |
| C1RL | CDC14B | 0.694066 | 3 | 0 | 3 |
| C1RL | WDR86 | 0.688899 | 3 | 0 | 3 |
| C1RL | UNC5C | 0.684953 | 3 | 0 | 3 |
| C1RL | MAML2 | 0.67917 | 3 | 0 | 3 |
| C1RL | CEP170 | 0.672423 | 3 | 0 | 3 |
| C1RL | LRRC8C | 0.671296 | 3 | 0 | 3 |
| C1RL | MNS1 | 0.664205 | 3 | 0 | 3 |
| C1RL | ITPR1 | 0.664189 | 3 | 0 | 3 |
| C1RL | CREB3L2 | 0.660624 | 3 | 0 | 3 |
| C1RL | BIN1 | 0.659577 | 4 | 0 | 4 |
| C1RL | CLIP2 | 0.658372 | 3 | 0 | 3 |
| C1RL | DMXL2 | 0.657721 | 6 | 0 | 6 |
For details and further investigation, click here
