| Full name: interferon related developmental regulator 1 | Alias Symbol: PC4|TIS7 | ||
| Type: protein-coding gene | Cytoband: 7q31.1 | ||
| Entrez ID: 3475 | HGNC ID: HGNC:5456 | Ensembl Gene: ENSG00000006652 | OMIM ID: 603502 |
| Drug and gene relationship at DGIdb | |||
Expression of IFRD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IFRD1 | 3475 | 202146_at | -0.3942 | 0.5119 | |
| GSE20347 | IFRD1 | 3475 | 202146_at | 0.1570 | 0.4254 | |
| GSE23400 | IFRD1 | 3475 | 202146_at | -0.1881 | 0.0955 | |
| GSE26886 | IFRD1 | 3475 | 202146_at | -0.0529 | 0.9152 | |
| GSE29001 | IFRD1 | 3475 | 202146_at | -0.0559 | 0.8951 | |
| GSE38129 | IFRD1 | 3475 | 202146_at | 0.1076 | 0.5126 | |
| GSE45670 | IFRD1 | 3475 | 202146_at | -0.2286 | 0.2135 | |
| GSE53622 | IFRD1 | 3475 | 68144 | -0.1725 | 0.0879 | |
| GSE53624 | IFRD1 | 3475 | 68144 | -0.2385 | 0.0012 | |
| GSE63941 | IFRD1 | 3475 | 202146_at | -0.2108 | 0.8603 | |
| GSE77861 | IFRD1 | 3475 | 202146_at | 0.0182 | 0.9702 | |
| GSE97050 | IFRD1 | 3475 | A_24_P137897 | -0.2277 | 0.4004 | |
| SRP007169 | IFRD1 | 3475 | RNAseq | -1.3372 | 0.0243 | |
| SRP008496 | IFRD1 | 3475 | RNAseq | -0.8971 | 0.0115 | |
| SRP064894 | IFRD1 | 3475 | RNAseq | -0.5920 | 0.0037 | |
| SRP133303 | IFRD1 | 3475 | RNAseq | -0.1043 | 0.5981 | |
| SRP159526 | IFRD1 | 3475 | RNAseq | -0.3684 | 0.0536 | |
| SRP193095 | IFRD1 | 3475 | RNAseq | -0.7046 | 0.0000 | |
| SRP219564 | IFRD1 | 3475 | RNAseq | -0.3183 | 0.3338 | |
| TCGA | IFRD1 | 3475 | RNAseq | -0.1136 | 0.1112 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by IFRD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IFRD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IFRD1 | 3475 | 10 | 2 | 18 | |
| GSE20123 | IFRD1 | 3475 | 11 | 2 | 17 | |
| GSE43470 | IFRD1 | 3475 | 6 | 1 | 36 | |
| GSE46452 | IFRD1 | 3475 | 8 | 1 | 50 | |
| GSE47630 | IFRD1 | 3475 | 7 | 4 | 29 | |
| GSE54993 | IFRD1 | 3475 | 3 | 8 | 59 | |
| GSE54994 | IFRD1 | 3475 | 12 | 5 | 36 | |
| GSE60625 | IFRD1 | 3475 | 0 | 0 | 11 | |
| GSE74703 | IFRD1 | 3475 | 6 | 1 | 29 | |
| GSE74704 | IFRD1 | 3475 | 7 | 2 | 11 | |
| TCGA | IFRD1 | 3475 | 37 | 16 | 43 |
Total number of gains: 107; Total number of losses: 42; Total Number of normals: 339.
Somatic mutations of IFRD1:
Generating mutation plots.
Highly correlated genes for IFRD1:
Showing all 19 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IFRD1 | FAM184A | 0.686742 | 3 | 0 | 3 |
| IFRD1 | KPNA5 | 0.611342 | 3 | 0 | 3 |
| IFRD1 | LRP2BP | 0.605332 | 3 | 0 | 3 |
| IFRD1 | PIK3C2A | 0.592903 | 3 | 0 | 3 |
| IFRD1 | PCMTD1 | 0.585309 | 4 | 0 | 3 |
| IFRD1 | RFK | 0.581467 | 3 | 0 | 3 |
| IFRD1 | RPS6KB1 | 0.576067 | 4 | 0 | 3 |
| IFRD1 | STK38L | 0.572957 | 4 | 0 | 3 |
| IFRD1 | OTUD6B | 0.569988 | 4 | 0 | 3 |
| IFRD1 | AIDA | 0.555041 | 3 | 0 | 3 |
| IFRD1 | NHLRC3 | 0.543539 | 4 | 0 | 3 |
| IFRD1 | IFT74 | 0.539561 | 4 | 0 | 3 |
| IFRD1 | PCF11 | 0.536835 | 4 | 0 | 3 |
| IFRD1 | JMJD1C | 0.531753 | 5 | 0 | 4 |
| IFRD1 | CRY1 | 0.519021 | 6 | 0 | 4 |
| IFRD1 | ARHGAP12 | 0.512436 | 5 | 0 | 3 |
| IFRD1 | TUBE1 | 0.507227 | 6 | 0 | 3 |
| IFRD1 | ZMYM2 | 0.506155 | 5 | 0 | 3 |
| IFRD1 | WASL | 0.50588 | 5 | 0 | 3 |
For details and further investigation, click here
