| Full name: SEC14 like lipid binding 4 | Alias Symbol: TAP3|dJ130H16.5 | ||
| Type: protein-coding gene | Cytoband: 22q12.2 | ||
| Entrez ID: 284904 | HGNC ID: HGNC:20627 | Ensembl Gene: ENSG00000133488 | OMIM ID: 612825 |
| Drug and gene relationship at DGIdb | |||
Expression of SEC14L4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SEC14L4 | 284904 | 239492_at | 0.6188 | 0.1306 | |
| GSE20347 | SEC14L4 | 284904 | 216402_at | 0.0343 | 0.7238 | |
| GSE23400 | SEC14L4 | 284904 | 216402_at | -0.0398 | 0.2350 | |
| GSE26886 | SEC14L4 | 284904 | 216402_at | 0.1951 | 0.0794 | |
| GSE29001 | SEC14L4 | 284904 | 216402_at | -0.0582 | 0.6958 | |
| GSE38129 | SEC14L4 | 284904 | 216402_at | -0.0065 | 0.9556 | |
| GSE45670 | SEC14L4 | 284904 | 239492_at | 0.3420 | 0.0789 | |
| GSE53622 | SEC14L4 | 284904 | 49756 | 0.0094 | 0.9213 | |
| GSE53624 | SEC14L4 | 284904 | 140712 | -0.2198 | 0.1692 | |
| GSE63941 | SEC14L4 | 284904 | 239492_at | 0.1933 | 0.8635 | |
| GSE77861 | SEC14L4 | 284904 | 239492_at | 0.1807 | 0.0981 | |
| GSE97050 | SEC14L4 | 284904 | A_33_P3372699 | 0.0609 | 0.7874 | |
| SRP133303 | SEC14L4 | 284904 | RNAseq | 0.7715 | 0.0012 | |
| SRP193095 | SEC14L4 | 284904 | RNAseq | 0.5520 | 0.0019 | |
| SRP219564 | SEC14L4 | 284904 | RNAseq | 3.1971 | 0.0000 | |
| TCGA | SEC14L4 | 284904 | RNAseq | 1.7017 | 0.0045 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by SEC14L4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SEC14L4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SEC14L4 | 284904 | 4 | 5 | 21 | |
| GSE20123 | SEC14L4 | 284904 | 4 | 4 | 22 | |
| GSE43470 | SEC14L4 | 284904 | 4 | 6 | 33 | |
| GSE46452 | SEC14L4 | 284904 | 31 | 1 | 27 | |
| GSE47630 | SEC14L4 | 284904 | 8 | 5 | 27 | |
| GSE54993 | SEC14L4 | 284904 | 3 | 6 | 61 | |
| GSE54994 | SEC14L4 | 284904 | 11 | 8 | 34 | |
| GSE60625 | SEC14L4 | 284904 | 5 | 0 | 6 | |
| GSE74703 | SEC14L4 | 284904 | 4 | 5 | 27 | |
| GSE74704 | SEC14L4 | 284904 | 1 | 1 | 18 | |
| TCGA | SEC14L4 | 284904 | 27 | 15 | 54 |
Total number of gains: 102; Total number of losses: 56; Total Number of normals: 330.
Somatic mutations of SEC14L4:
Generating mutation plots.
Highly correlated genes for SEC14L4:
Showing top 20/450 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SEC14L4 | PRKAR1B | 0.795989 | 3 | 0 | 3 |
| SEC14L4 | KRTAP4-1 | 0.776175 | 3 | 0 | 3 |
| SEC14L4 | PGLYRP1 | 0.758546 | 3 | 0 | 3 |
| SEC14L4 | KIR3DL3 | 0.733088 | 6 | 0 | 5 |
| SEC14L4 | SORCS2 | 0.733012 | 3 | 0 | 3 |
| SEC14L4 | RENBP | 0.728983 | 3 | 0 | 3 |
| SEC14L4 | CYP2D6 | 0.716827 | 5 | 0 | 5 |
| SEC14L4 | SURF2 | 0.715614 | 3 | 0 | 3 |
| SEC14L4 | TNFSF11 | 0.711101 | 4 | 0 | 4 |
| SEC14L4 | OR10C1 | 0.704076 | 5 | 0 | 5 |
| SEC14L4 | FAM153A | 0.702541 | 3 | 0 | 3 |
| SEC14L4 | PTK2B | 0.699172 | 3 | 0 | 3 |
| SEC14L4 | ABCC6 | 0.699001 | 4 | 0 | 3 |
| SEC14L4 | DHRS2 | 0.698228 | 3 | 0 | 3 |
| SEC14L4 | HGD | 0.693206 | 4 | 0 | 4 |
| SEC14L4 | TEKT2 | 0.692276 | 3 | 0 | 3 |
| SEC14L4 | TLE6 | 0.691911 | 5 | 0 | 5 |
| SEC14L4 | LHFPL5 | 0.691872 | 3 | 0 | 3 |
| SEC14L4 | SIX6 | 0.691019 | 5 | 0 | 5 |
| SEC14L4 | SPTBN5 | 0.688579 | 4 | 0 | 3 |
For details and further investigation, click here
