| Full name: teneurin transmembrane protein 2 | Alias Symbol: KIAA1127|Ten-M2 | ||
| Type: protein-coding gene | Cytoband: 5q34 | ||
| Entrez ID: 57451 | HGNC ID: HGNC:29943 | Ensembl Gene: ENSG00000145934 | OMIM ID: 610119 |
| Drug and gene relationship at DGIdb | |||
Expression of TENM2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TENM2 | 57451 | 231867_at | 0.5613 | 0.8724 | |
| GSE26886 | TENM2 | 57451 | 231867_at | 2.8393 | 0.0005 | |
| GSE45670 | TENM2 | 57451 | 231867_at | 2.1065 | 0.0013 | |
| GSE53622 | TENM2 | 57451 | 107228 | 2.0380 | 0.0000 | |
| GSE53624 | TENM2 | 57451 | 107228 | 2.3472 | 0.0000 | |
| GSE63941 | TENM2 | 57451 | 231867_at | 1.8369 | 0.3241 | |
| GSE77861 | TENM2 | 57451 | 231867_at | 2.7248 | 0.0002 | |
| SRP007169 | TENM2 | 57451 | RNAseq | 3.6550 | 0.0000 | |
| SRP008496 | TENM2 | 57451 | RNAseq | 3.7488 | 0.0000 | |
| SRP064894 | TENM2 | 57451 | RNAseq | 1.6988 | 0.0001 | |
| SRP133303 | TENM2 | 57451 | RNAseq | 3.3192 | 0.0000 | |
| SRP159526 | TENM2 | 57451 | RNAseq | 2.1991 | 0.0045 | |
| SRP193095 | TENM2 | 57451 | RNAseq | 2.6408 | 0.0000 |
Upregulated datasets: 11; Downregulated datasets: 0.
Survival by TENM2 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of TENM2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TENM2 | 57451 | 0 | 12 | 18 | |
| GSE20123 | TENM2 | 57451 | 0 | 12 | 18 | |
| GSE43470 | TENM2 | 57451 | 2 | 9 | 32 | |
| GSE46452 | TENM2 | 57451 | 0 | 27 | 32 | |
| GSE47630 | TENM2 | 57451 | 0 | 20 | 20 | |
| GSE54993 | TENM2 | 57451 | 9 | 2 | 59 | |
| GSE54994 | TENM2 | 57451 | 2 | 15 | 36 | |
| GSE60625 | TENM2 | 57451 | 1 | 0 | 10 | |
| GSE74703 | TENM2 | 57451 | 2 | 7 | 27 | |
| GSE74704 | TENM2 | 57451 | 0 | 7 | 13 | |
| TCGA | TENM2 | 57451 | 7 | 36 | 53 |
Total number of gains: 23; Total number of losses: 147; Total Number of normals: 318.
Somatic mutations of TENM2:
Generating mutation plots.
Highly correlated genes for TENM2:
Showing top 20/1064 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TENM2 | FSCN1 | 0.812221 | 6 | 0 | 6 |
| TENM2 | PDPN | 0.81075 | 4 | 0 | 4 |
| TENM2 | CD276 | 0.799733 | 3 | 0 | 3 |
| TENM2 | BLACAT1 | 0.781312 | 4 | 0 | 4 |
| TENM2 | SLC3A2 | 0.774264 | 5 | 0 | 5 |
| TENM2 | HMGA2 | 0.763247 | 4 | 0 | 4 |
| TENM2 | SLC20A1 | 0.762934 | 3 | 0 | 3 |
| TENM2 | RBP1 | 0.762909 | 6 | 0 | 6 |
| TENM2 | KIF14 | 0.753836 | 5 | 0 | 5 |
| TENM2 | MYH9 | 0.744233 | 4 | 0 | 4 |
| TENM2 | MYO5A | 0.743971 | 6 | 0 | 6 |
| TENM2 | WDR54 | 0.743784 | 6 | 0 | 6 |
| TENM2 | PTHLH | 0.743293 | 7 | 0 | 6 |
| TENM2 | F2RL1 | 0.743085 | 4 | 0 | 3 |
| TENM2 | SPP1 | 0.742541 | 5 | 0 | 5 |
| TENM2 | BORA | 0.739775 | 3 | 0 | 3 |
| TENM2 | MFAP2 | 0.73859 | 5 | 0 | 5 |
| TENM2 | XPR1 | 0.73802 | 6 | 0 | 6 |
| TENM2 | TNFAIP8L1 | 0.737945 | 3 | 0 | 3 |
| TENM2 | KIF4A | 0.737628 | 5 | 0 | 5 |
For details and further investigation, click here
