| Full name: interleukin 10 receptor subunit alpha | Alias Symbol: HIL-10R|CDW210A|CD210a|CD210 | ||
| Type: protein-coding gene | Cytoband: 11q23.3 | ||
| Entrez ID: 3587 | HGNC ID: HGNC:5964 | Ensembl Gene: ENSG00000110324 | OMIM ID: 146933 |
| Drug and gene relationship at DGIdb | |||
IL10RA involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04630 | Jak-STAT signaling pathway | |
| hsa05145 | Toxoplasmosis | |
| hsa05152 | Tuberculosis | |
| hsa05169 | Epstein-Barr virus infection |
Expression of IL10RA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IL10RA | 3587 | 204912_at | 0.2315 | 0.8784 | |
| GSE20347 | IL10RA | 3587 | 204912_at | 0.0221 | 0.9354 | |
| GSE23400 | IL10RA | 3587 | 204912_at | 0.0473 | 0.6488 | |
| GSE26886 | IL10RA | 3587 | 204912_at | 0.1377 | 0.7539 | |
| GSE29001 | IL10RA | 3587 | 204912_at | 0.2601 | 0.3759 | |
| GSE38129 | IL10RA | 3587 | 204912_at | -0.1414 | 0.6191 | |
| GSE45670 | IL10RA | 3587 | 204912_at | -0.4859 | 0.1170 | |
| GSE53622 | IL10RA | 3587 | 84018 | -0.2103 | 0.2600 | |
| GSE53624 | IL10RA | 3587 | 84018 | -0.3522 | 0.0541 | |
| GSE63941 | IL10RA | 3587 | 204912_at | 0.0871 | 0.6228 | |
| GSE77861 | IL10RA | 3587 | 204912_at | -0.1500 | 0.0657 | |
| GSE97050 | IL10RA | 3587 | A_23_P203173 | 0.3528 | 0.2852 | |
| SRP007169 | IL10RA | 3587 | RNAseq | 1.1670 | 0.1843 | |
| SRP008496 | IL10RA | 3587 | RNAseq | 0.8385 | 0.1250 | |
| SRP064894 | IL10RA | 3587 | RNAseq | 0.3877 | 0.2547 | |
| SRP133303 | IL10RA | 3587 | RNAseq | -0.3600 | 0.2246 | |
| SRP159526 | IL10RA | 3587 | RNAseq | -0.3157 | 0.7096 | |
| SRP193095 | IL10RA | 3587 | RNAseq | 0.4084 | 0.1339 | |
| SRP219564 | IL10RA | 3587 | RNAseq | 0.7319 | 0.0798 | |
| TCGA | IL10RA | 3587 | RNAseq | -0.0669 | 0.6245 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IL10RA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IL10RA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IL10RA | 3587 | 2 | 11 | 17 | |
| GSE20123 | IL10RA | 3587 | 2 | 11 | 17 | |
| GSE43470 | IL10RA | 3587 | 2 | 9 | 32 | |
| GSE46452 | IL10RA | 3587 | 3 | 26 | 30 | |
| GSE47630 | IL10RA | 3587 | 2 | 19 | 19 | |
| GSE54993 | IL10RA | 3587 | 10 | 0 | 60 | |
| GSE54994 | IL10RA | 3587 | 5 | 19 | 29 | |
| GSE60625 | IL10RA | 3587 | 0 | 3 | 8 | |
| GSE74703 | IL10RA | 3587 | 1 | 6 | 29 | |
| GSE74704 | IL10RA | 3587 | 1 | 7 | 12 | |
| TCGA | IL10RA | 3587 | 5 | 50 | 41 |
Total number of gains: 33; Total number of losses: 161; Total Number of normals: 294.
Somatic mutations of IL10RA:
Generating mutation plots.
Highly correlated genes for IL10RA:
Showing top 20/261 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IL10RA | CD37 | 0.802787 | 7 | 0 | 7 |
| IL10RA | PIK3CG | 0.785376 | 7 | 0 | 6 |
| IL10RA | DOCK2 | 0.773833 | 11 | 0 | 11 |
| IL10RA | SLAMF6 | 0.773464 | 4 | 0 | 4 |
| IL10RA | MPEG1 | 0.770943 | 5 | 0 | 4 |
| IL10RA | CD28 | 0.767943 | 4 | 0 | 4 |
| IL10RA | TNFSF8 | 0.758965 | 4 | 0 | 3 |
| IL10RA | CD48 | 0.757543 | 12 | 0 | 12 |
| IL10RA | MS4A4E | 0.753675 | 3 | 0 | 3 |
| IL10RA | SLA | 0.743959 | 10 | 0 | 9 |
| IL10RA | CYTIP | 0.740939 | 10 | 0 | 9 |
| IL10RA | C1orf162 | 0.733409 | 6 | 0 | 5 |
| IL10RA | GMFG | 0.732745 | 11 | 0 | 10 |
| IL10RA | ARHGDIB | 0.729849 | 9 | 0 | 9 |
| IL10RA | CCR5 | 0.726144 | 8 | 0 | 7 |
| IL10RA | MFNG | 0.725429 | 7 | 0 | 6 |
| IL10RA | NRROS | 0.724497 | 4 | 0 | 4 |
| IL10RA | GIMAP2 | 0.723918 | 7 | 0 | 7 |
| IL10RA | RNASE6 | 0.72249 | 9 | 0 | 9 |
| IL10RA | HSH2D | 0.717735 | 4 | 0 | 4 |
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