Full name: C-C motif chemokine receptor 5 (gene/pseudogene)	Alias Symbol: CKR-5|CC-CKR-5|CKR5|CD195|IDDM22
Type: protein-coding gene	Cytoband: 3p21.31
Entrez ID: 1234	HGNC ID: HGNC:1606	Ensembl Gene: ENSG00000160791	OMIM ID: 601373
Drug and gene relationship at DGIdb

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CCR5 involved pathways:

KEGG pathway	Description	View
hsa04062	Chemokine signaling pathway	View
hsa05145	Toxoplasmosis	View

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Expression of CCR5:

 

Dataset	Gene	EntrezID	Probe	Log2FC	Adj.pValue	Expression
GSE17351	CCR5	1234	206991_s_at	0.5336	0.3799	Show
GSE20347	CCR5	1234	206991_s_at	0.2568	0.0870	Show
GSE23400	CCR5	1234	206991_s_at	0.0680	0.1895	Show
GSE26886	CCR5	1234	206991_s_at	-0.8823	0.0103	Show
GSE29001	CCR5	1234	206991_s_at	0.1290	0.5601	Show
GSE38129	CCR5	1234	206991_s_at	0.1957	0.2366	Show
GSE45670	CCR5	1234	206991_s_at	0.0566	0.8656	Show
GSE53622	CCR5	1234	62648	-0.9975	0.0000	Show
GSE53624	CCR5	1234	24244	-0.0418	0.8286	Show
GSE63941	CCR5	1234	206991_s_at	0.2708	0.1161	Show
GSE77861	CCR5	1234	206991_s_at	-0.0257	0.8502	Show
GSE97050	CCR5	1234	A_23_P412321	0.5548	0.2463	Show
SRP064894	CCR5	1234	RNAseq	0.3895	0.2208	Show
SRP133303	CCR5	1234	RNAseq	0.0347	0.8979	Show
SRP159526	CCR5	1234	RNAseq	-0.5650	0.5388	Show
SRP193095	CCR5	1234	RNAseq	-0.4080	0.0348	Show
SRP219564	CCR5	1234	RNAseq	0.9868	0.0722	Show
TCGA	CCR5	1234	RNAseq	0.1723	0.4256	Show

Upregulated datasets: 0; Downregulated datasets: 0.  Download Data

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Survival by CCR5 expression:

 

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Copy number change of CCR5:

 

Dataset	Gene	EntrezID	Gain	Loss	Normal	Detail
GSE15526	CCR5	1234	0	17	13	Show
GSE20123	CCR5	1234	0	18	12	Show
GSE43470	CCR5	1234	0	20	23	Show
GSE46452	CCR5	1234	2	17	40	Show
GSE47630	CCR5	1234	2	23	15	Show
GSE54993	CCR5	1234	7	2	61	Show
GSE54994	CCR5	1234	0	36	17	Show
GSE60625	CCR5	1234	5	0	6	Show
GSE74703	CCR5	1234	0	15	21	Show
GSE74704	CCR5	1234	0	12	8	Show
TCGA	CCR5	1234	1	75	20	Show

Total number of gains: 17; Total number of losses: 235; Total Number of normals: 236.  Download Data

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Somatic mutations of CCR5:

 

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Highly correlated genes for CCR5:

 

Showing top 20/310 corelated genes with mean PCC>0.5.

Gene1	Gene2	Mean PCC	Num. Datasets	Num. PCC<0	Num. PCC>0.5
CCR5	SNX20	0.768984	5	0	5
CCR5	SAMD3	0.75164	5	0	5
CCR5	SLA	0.748922	10	0	10
CCR5	HLA-DOA	0.744906	3	0	3
CCR5	IL2RB	0.737482	9	0	7
CCR5	IL10RA	0.726144	8	0	7
CCR5	CD53	0.716565	9	0	8
CCR5	GPRIN3	0.714942	4	0	4
CCR5	CCR1	0.711016	9	0	9
CCR5	SASH3	0.705799	11	0	10
CCR5	PTPN7	0.705638	9	0	8
CCR5	CYTH4	0.6997	8	0	8
CCR5	MRC1	0.698889	3	0	3
CCR5	FCGR1B	0.698166	6	0	6
CCR5	LCK	0.696061	9	0	8
CCR5	NKG7	0.694783	9	0	8
CCR5	IRF8	0.694411	9	0	9
CCR5	CYTIP	0.693389	10	0	9
CCR5	TLR8	0.690863	4	0	4
CCR5	PRF1	0.689594	9	0	9

For details and further investigation, click here