| Full name: MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 22q13.1 | ||
| Entrez ID: 4242 | HGNC ID: HGNC:7038 | Ensembl Gene: ENSG00000100060 | OMIM ID: 602577 |
| Drug and gene relationship at DGIdb | |||
MFNG involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04330 | Notch signaling pathway |
Expression of MFNG:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MFNG | 4242 | 204153_s_at | -0.0754 | 0.9537 | |
| GSE20347 | MFNG | 4242 | 213783_at | -0.1892 | 0.0172 | |
| GSE23400 | MFNG | 4242 | 213783_at | -0.1712 | 0.0000 | |
| GSE26886 | MFNG | 4242 | 213783_at | -0.0504 | 0.7602 | |
| GSE29001 | MFNG | 4242 | 204153_s_at | 0.0154 | 0.9620 | |
| GSE38129 | MFNG | 4242 | 204153_s_at | -0.2781 | 0.2033 | |
| GSE45670 | MFNG | 4242 | 204153_s_at | -0.0997 | 0.6986 | |
| GSE53622 | MFNG | 4242 | 30468 | -0.3620 | 0.0107 | |
| GSE53624 | MFNG | 4242 | 27832 | -0.2109 | 0.1437 | |
| GSE63941 | MFNG | 4242 | 204152_s_at | 0.0205 | 0.9513 | |
| GSE77861 | MFNG | 4242 | 213783_at | -0.1419 | 0.4044 | |
| GSE97050 | MFNG | 4242 | A_23_P103104 | 0.4296 | 0.2584 | |
| SRP007169 | MFNG | 4242 | RNAseq | 0.3188 | 0.6731 | |
| SRP064894 | MFNG | 4242 | RNAseq | 0.4366 | 0.1924 | |
| SRP133303 | MFNG | 4242 | RNAseq | -0.6747 | 0.0023 | |
| SRP159526 | MFNG | 4242 | RNAseq | -0.5542 | 0.3993 | |
| SRP193095 | MFNG | 4242 | RNAseq | 0.2415 | 0.2808 | |
| SRP219564 | MFNG | 4242 | RNAseq | 0.2151 | 0.6087 | |
| TCGA | MFNG | 4242 | RNAseq | -0.4329 | 0.0089 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MFNG expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MFNG:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MFNG | 4242 | 6 | 6 | 18 | |
| GSE20123 | MFNG | 4242 | 6 | 5 | 19 | |
| GSE43470 | MFNG | 4242 | 4 | 6 | 33 | |
| GSE46452 | MFNG | 4242 | 32 | 2 | 25 | |
| GSE47630 | MFNG | 4242 | 9 | 4 | 27 | |
| GSE54993 | MFNG | 4242 | 3 | 6 | 61 | |
| GSE54994 | MFNG | 4242 | 9 | 8 | 36 | |
| GSE60625 | MFNG | 4242 | 5 | 0 | 6 | |
| GSE74703 | MFNG | 4242 | 4 | 4 | 28 | |
| GSE74704 | MFNG | 4242 | 3 | 2 | 15 | |
| TCGA | MFNG | 4242 | 27 | 15 | 54 |
Total number of gains: 108; Total number of losses: 58; Total Number of normals: 322.
Somatic mutations of MFNG:
Generating mutation plots.
Highly correlated genes for MFNG:
Showing top 20/222 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MFNG | EMID1 | 0.752547 | 3 | 0 | 3 |
| MFNG | SCN3A | 0.751429 | 3 | 0 | 3 |
| MFNG | MEI1 | 0.740353 | 4 | 0 | 4 |
| MFNG | SIRPD | 0.740275 | 3 | 0 | 3 |
| MFNG | IL10RA | 0.725429 | 7 | 0 | 6 |
| MFNG | GMFG | 0.722264 | 6 | 0 | 5 |
| MFNG | ZNF831 | 0.71911 | 5 | 0 | 5 |
| MFNG | ARHGAP30 | 0.715635 | 4 | 0 | 4 |
| MFNG | THEMIS2 | 0.707721 | 4 | 0 | 3 |
| MFNG | AIF1 | 0.706405 | 5 | 0 | 5 |
| MFNG | TMIGD2 | 0.705371 | 3 | 0 | 3 |
| MFNG | CD48 | 0.696505 | 7 | 0 | 6 |
| MFNG | GIMAP2 | 0.69353 | 5 | 0 | 5 |
| MFNG | SLA | 0.692549 | 6 | 0 | 6 |
| MFNG | BTNL9 | 0.683598 | 3 | 0 | 3 |
| MFNG | CYBB | 0.681339 | 5 | 0 | 5 |
| MFNG | BTBD19 | 0.677157 | 3 | 0 | 3 |
| MFNG | ENTPD1 | 0.676683 | 4 | 0 | 4 |
| MFNG | ITIH3 | 0.674996 | 3 | 0 | 3 |
| MFNG | MPEG1 | 0.671984 | 5 | 0 | 4 |
For details and further investigation, click here
