| Full name: GPRIN family member 3 | Alias Symbol: GRIN3|FLJ42625 | ||
| Type: protein-coding gene | Cytoband: 4q22.1 | ||
| Entrez ID: 285513 | HGNC ID: HGNC:27733 | Ensembl Gene: ENSG00000185477 | OMIM ID: 611241 |
| Drug and gene relationship at DGIdb | |||
Expression of GPRIN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPRIN3 | 285513 | 240173_at | 0.0267 | 0.9793 | |
| GSE26886 | GPRIN3 | 285513 | 232687_at | -0.2767 | 0.2213 | |
| GSE45670 | GPRIN3 | 285513 | 232687_at | 0.0493 | 0.8655 | |
| GSE53622 | GPRIN3 | 285513 | 13547 | 0.1147 | 0.2784 | |
| GSE53624 | GPRIN3 | 285513 | 13547 | 0.2575 | 0.0046 | |
| GSE63941 | GPRIN3 | 285513 | 232687_at | -0.1583 | 0.8386 | |
| GSE77861 | GPRIN3 | 285513 | 232687_at | -0.0025 | 0.9763 | |
| GSE97050 | GPRIN3 | 285513 | A_24_P76649 | 0.3572 | 0.4126 | |
| SRP007169 | GPRIN3 | 285513 | RNAseq | 1.1261 | 0.1035 | |
| SRP008496 | GPRIN3 | 285513 | RNAseq | 1.1273 | 0.0051 | |
| SRP064894 | GPRIN3 | 285513 | RNAseq | 0.8291 | 0.0288 | |
| SRP133303 | GPRIN3 | 285513 | RNAseq | 0.2186 | 0.2946 | |
| SRP159526 | GPRIN3 | 285513 | RNAseq | -0.1428 | 0.8126 | |
| SRP193095 | GPRIN3 | 285513 | RNAseq | -0.0989 | 0.7321 | |
| SRP219564 | GPRIN3 | 285513 | RNAseq | 0.2692 | 0.6261 | |
| TCGA | GPRIN3 | 285513 | RNAseq | -0.6118 | 0.0003 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by GPRIN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPRIN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPRIN3 | 285513 | 0 | 12 | 18 | |
| GSE20123 | GPRIN3 | 285513 | 0 | 12 | 18 | |
| GSE43470 | GPRIN3 | 285513 | 0 | 14 | 29 | |
| GSE46452 | GPRIN3 | 285513 | 1 | 36 | 22 | |
| GSE47630 | GPRIN3 | 285513 | 0 | 20 | 20 | |
| GSE54993 | GPRIN3 | 285513 | 8 | 0 | 62 | |
| GSE54994 | GPRIN3 | 285513 | 2 | 10 | 41 | |
| GSE60625 | GPRIN3 | 285513 | 0 | 0 | 11 | |
| GSE74703 | GPRIN3 | 285513 | 0 | 12 | 24 | |
| GSE74704 | GPRIN3 | 285513 | 0 | 7 | 13 | |
| TCGA | GPRIN3 | 285513 | 10 | 37 | 49 |
Total number of gains: 21; Total number of losses: 160; Total Number of normals: 307.
Somatic mutations of GPRIN3:
Generating mutation plots.
Highly correlated genes for GPRIN3:
Showing top 20/220 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPRIN3 | DOK1 | 0.798449 | 3 | 0 | 3 |
| GPRIN3 | SLAMF7 | 0.764121 | 3 | 0 | 3 |
| GPRIN3 | ADCYAP1 | 0.763759 | 3 | 0 | 3 |
| GPRIN3 | IL2RG | 0.759599 | 3 | 0 | 3 |
| GPRIN3 | APOBR | 0.751927 | 3 | 0 | 3 |
| GPRIN3 | CD53 | 0.722574 | 5 | 0 | 5 |
| GPRIN3 | LMAN1 | 0.716046 | 3 | 0 | 3 |
| GPRIN3 | CCR5 | 0.714942 | 4 | 0 | 4 |
| GPRIN3 | NCKAP1L | 0.70912 | 5 | 0 | 4 |
| GPRIN3 | CASP3 | 0.70843 | 3 | 0 | 3 |
| GPRIN3 | ST8SIA4 | 0.698158 | 6 | 0 | 5 |
| GPRIN3 | SAMSN1 | 0.698145 | 6 | 0 | 5 |
| GPRIN3 | SH2D3C | 0.69702 | 3 | 0 | 3 |
| GPRIN3 | HGF | 0.691474 | 3 | 0 | 3 |
| GPRIN3 | ITGB2 | 0.690482 | 6 | 0 | 6 |
| GPRIN3 | GPR65 | 0.690016 | 6 | 0 | 5 |
| GPRIN3 | NEK6 | 0.689001 | 3 | 0 | 3 |
| GPRIN3 | TYROBP | 0.686796 | 5 | 0 | 5 |
| GPRIN3 | SCML4 | 0.685221 | 3 | 0 | 3 |
| GPRIN3 | HLA-DMB | 0.684826 | 6 | 0 | 5 |
For details and further investigation, click here
