| Full name: CD3d molecule | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q23.3 | ||
| Entrez ID: 915 | HGNC ID: HGNC:1673 | Ensembl Gene: ENSG00000167286 | OMIM ID: 186790 |
| Drug and gene relationship at DGIdb | |||
CD3D involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05142 | Chagas disease (American trypanosomiasis) | |
| hsa05162 | Measles | |
| hsa05166 | HTLV-I infection |
Expression of CD3D:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CD3D | 915 | 213539_at | 0.2347 | 0.8536 | |
| GSE20347 | CD3D | 915 | 213539_at | -0.4511 | 0.0113 | |
| GSE23400 | CD3D | 915 | 213539_at | -0.2080 | 0.0140 | |
| GSE26886 | CD3D | 915 | 213539_at | -0.1037 | 0.7871 | |
| GSE29001 | CD3D | 915 | 213539_at | -0.1520 | 0.7073 | |
| GSE38129 | CD3D | 915 | 213539_at | -0.3544 | 0.0544 | |
| GSE45670 | CD3D | 915 | 213539_at | 0.0006 | 0.9986 | |
| GSE53622 | CD3D | 915 | 40336 | -0.1410 | 0.5069 | |
| GSE53624 | CD3D | 915 | 40336 | -0.4030 | 0.0152 | |
| GSE63941 | CD3D | 915 | 213539_at | 0.5558 | 0.0128 | |
| GSE77861 | CD3D | 915 | 213539_at | -0.4147 | 0.0493 | |
| GSE97050 | CD3D | 915 | A_33_P3375541 | 0.8326 | 0.1774 | |
| SRP064894 | CD3D | 915 | RNAseq | -0.1971 | 0.5941 | |
| SRP133303 | CD3D | 915 | RNAseq | -0.4279 | 0.2787 | |
| SRP159526 | CD3D | 915 | RNAseq | -0.9874 | 0.2992 | |
| SRP193095 | CD3D | 915 | RNAseq | -0.6140 | 0.0189 | |
| SRP219564 | CD3D | 915 | RNAseq | 0.4123 | 0.4390 | |
| TCGA | CD3D | 915 | RNAseq | 0.2192 | 0.3877 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CD3D expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CD3D:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CD3D | 915 | 2 | 11 | 17 | |
| GSE20123 | CD3D | 915 | 2 | 11 | 17 | |
| GSE43470 | CD3D | 915 | 2 | 9 | 32 | |
| GSE46452 | CD3D | 915 | 3 | 26 | 30 | |
| GSE47630 | CD3D | 915 | 2 | 19 | 19 | |
| GSE54993 | CD3D | 915 | 10 | 0 | 60 | |
| GSE54994 | CD3D | 915 | 5 | 19 | 29 | |
| GSE60625 | CD3D | 915 | 0 | 3 | 8 | |
| GSE74703 | CD3D | 915 | 1 | 6 | 29 | |
| GSE74704 | CD3D | 915 | 1 | 7 | 12 | |
| TCGA | CD3D | 915 | 6 | 49 | 41 |
Total number of gains: 34; Total number of losses: 160; Total Number of normals: 294.
Somatic mutations of CD3D:
Generating mutation plots.
Highly correlated genes for CD3D:
Showing top 20/427 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CD3D | GPR174 | 0.878847 | 3 | 0 | 3 |
| CD3D | CD2 | 0.863985 | 12 | 0 | 12 |
| CD3D | CCR4 | 0.80053 | 3 | 0 | 3 |
| CD3D | GPR171 | 0.789144 | 11 | 0 | 11 |
| CD3D | CD48 | 0.784232 | 12 | 0 | 11 |
| CD3D | IL2RG | 0.767806 | 10 | 0 | 9 |
| CD3D | LCK | 0.761946 | 12 | 0 | 11 |
| CD3D | GZMK | 0.758441 | 9 | 0 | 9 |
| CD3D | IKZF3 | 0.754654 | 8 | 0 | 8 |
| CD3D | CORO1A | 0.751672 | 13 | 0 | 12 |
| CD3D | ARHGAP9 | 0.750707 | 7 | 0 | 7 |
| CD3D | IL2RB | 0.747715 | 11 | 0 | 11 |
| CD3D | PTPRC | 0.746084 | 10 | 0 | 10 |
| CD3D | CD96 | 0.737389 | 12 | 0 | 10 |
| CD3D | CD3E | 0.730095 | 10 | 0 | 7 |
| CD3D | HCST | 0.729995 | 8 | 0 | 8 |
| CD3D | ACAP1 | 0.729441 | 8 | 0 | 7 |
| CD3D | NKG7 | 0.728885 | 12 | 0 | 10 |
| CD3D | SLAMF6 | 0.728637 | 7 | 0 | 6 |
| CD3D | CD52 | 0.725289 | 12 | 0 | 10 |
For details and further investigation, click here
