| Full name: inturned planar cell polarity protein | Alias Symbol: KIAA1284|CPLANE4 | ||
| Type: protein-coding gene | Cytoband: 4q28.1 | ||
| Entrez ID: 27152 | HGNC ID: HGNC:29239 | Ensembl Gene: ENSG00000164066 | OMIM ID: 610621 |
| Drug and gene relationship at DGIdb | |||
Expression of INTU:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | INTU | 27152 | 228946_at | 0.0262 | 0.9779 | |
| GSE26886 | INTU | 27152 | 228946_at | -0.0584 | 0.9052 | |
| GSE45670 | INTU | 27152 | 228946_at | -0.2879 | 0.1912 | |
| GSE53622 | INTU | 27152 | 80168 | -0.4464 | 0.0001 | |
| GSE53624 | INTU | 27152 | 80168 | -0.3764 | 0.0000 | |
| GSE63941 | INTU | 27152 | 228946_at | -0.3941 | 0.5863 | |
| GSE77861 | INTU | 27152 | 228946_at | 0.0048 | 0.9880 | |
| GSE97050 | INTU | 27152 | A_33_P3273599 | -0.3907 | 0.2273 | |
| SRP007169 | INTU | 27152 | RNAseq | 0.7619 | 0.0585 | |
| SRP008496 | INTU | 27152 | RNAseq | 0.6062 | 0.0351 | |
| SRP064894 | INTU | 27152 | RNAseq | -0.1668 | 0.4465 | |
| SRP133303 | INTU | 27152 | RNAseq | 0.1721 | 0.0839 | |
| SRP159526 | INTU | 27152 | RNAseq | 0.1044 | 0.7580 | |
| SRP193095 | INTU | 27152 | RNAseq | 0.2699 | 0.0386 | |
| SRP219564 | INTU | 27152 | RNAseq | -0.3635 | 0.2534 | |
| TCGA | INTU | 27152 | RNAseq | -0.0882 | 0.4709 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by INTU expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of INTU:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | INTU | 27152 | 0 | 12 | 18 | |
| GSE20123 | INTU | 27152 | 0 | 12 | 18 | |
| GSE43470 | INTU | 27152 | 0 | 13 | 30 | |
| GSE46452 | INTU | 27152 | 1 | 36 | 22 | |
| GSE47630 | INTU | 27152 | 0 | 22 | 18 | |
| GSE54993 | INTU | 27152 | 9 | 0 | 61 | |
| GSE54994 | INTU | 27152 | 1 | 11 | 41 | |
| GSE60625 | INTU | 27152 | 0 | 1 | 10 | |
| GSE74703 | INTU | 27152 | 0 | 11 | 25 | |
| GSE74704 | INTU | 27152 | 0 | 6 | 14 | |
| TCGA | INTU | 27152 | 8 | 35 | 53 |
Total number of gains: 19; Total number of losses: 159; Total Number of normals: 310.
Somatic mutations of INTU:
Generating mutation plots.
Highly correlated genes for INTU:
Showing top 20/114 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| INTU | PPP3CB | 0.775168 | 3 | 0 | 3 |
| INTU | ZMYND11 | 0.751406 | 3 | 0 | 3 |
| INTU | AKAP12 | 0.750599 | 3 | 0 | 3 |
| INTU | PDK3 | 0.747335 | 3 | 0 | 3 |
| INTU | SOCS5 | 0.730683 | 3 | 0 | 3 |
| INTU | PNISR | 0.718925 | 4 | 0 | 4 |
| INTU | SCAI | 0.71788 | 3 | 0 | 3 |
| INTU | CYP2U1 | 0.717399 | 3 | 0 | 3 |
| INTU | DMTF1 | 0.714768 | 3 | 0 | 3 |
| INTU | KCNMA1 | 0.713275 | 3 | 0 | 3 |
| INTU | ELMO2 | 0.703737 | 3 | 0 | 3 |
| INTU | SCMH1 | 0.697193 | 3 | 0 | 3 |
| INTU | STARD9 | 0.696565 | 3 | 0 | 3 |
| INTU | EZH1 | 0.696301 | 4 | 0 | 3 |
| INTU | TCEAL4 | 0.683907 | 3 | 0 | 3 |
| INTU | SLAIN1 | 0.683404 | 3 | 0 | 3 |
| INTU | ARL4C | 0.681303 | 3 | 0 | 3 |
| INTU | ZMYM2 | 0.677051 | 3 | 0 | 3 |
| INTU | GPRC5B | 0.674374 | 3 | 0 | 3 |
| INTU | ANTXR2 | 0.671702 | 3 | 0 | 3 |
For details and further investigation, click here
