| Full name: IQ motif containing B1 | Alias Symbol: KIAA0036|NPHP5|SLSN5 | ||
| Type: protein-coding gene | Cytoband: 3q13.33 | ||
| Entrez ID: 9657 | HGNC ID: HGNC:28949 | Ensembl Gene: ENSG00000173226 | OMIM ID: 609237 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of IQCB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IQCB1 | 9657 | 211707_s_at | 0.7805 | 0.1033 | |
| GSE20347 | IQCB1 | 9657 | 205995_x_at | 0.7850 | 0.0000 | |
| GSE23400 | IQCB1 | 9657 | 205995_x_at | 0.3334 | 0.0000 | |
| GSE26886 | IQCB1 | 9657 | 205995_x_at | 1.3971 | 0.0000 | |
| GSE29001 | IQCB1 | 9657 | 211707_s_at | 0.6321 | 0.0520 | |
| GSE38129 | IQCB1 | 9657 | 205995_x_at | 0.6295 | 0.0000 | |
| GSE45670 | IQCB1 | 9657 | 211707_s_at | 0.5540 | 0.0038 | |
| GSE53622 | IQCB1 | 9657 | 12479 | 0.5926 | 0.0000 | |
| GSE53624 | IQCB1 | 9657 | 12479 | 0.6026 | 0.0000 | |
| GSE63941 | IQCB1 | 9657 | 205995_x_at | 1.2040 | 0.0098 | |
| GSE77861 | IQCB1 | 9657 | 205995_x_at | 0.3539 | 0.1403 | |
| GSE97050 | IQCB1 | 9657 | A_23_P84140 | 0.3825 | 0.2096 | |
| SRP007169 | IQCB1 | 9657 | RNAseq | 1.3720 | 0.0001 | |
| SRP008496 | IQCB1 | 9657 | RNAseq | 1.4134 | 0.0000 | |
| SRP064894 | IQCB1 | 9657 | RNAseq | 0.7015 | 0.0032 | |
| SRP133303 | IQCB1 | 9657 | RNAseq | 0.5013 | 0.0082 | |
| SRP159526 | IQCB1 | 9657 | RNAseq | 0.6839 | 0.0013 | |
| SRP193095 | IQCB1 | 9657 | RNAseq | 0.4984 | 0.0000 | |
| SRP219564 | IQCB1 | 9657 | RNAseq | 0.3664 | 0.1976 | |
| TCGA | IQCB1 | 9657 | RNAseq | 0.2104 | 0.0062 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by IQCB1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IQCB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IQCB1 | 9657 | 18 | 0 | 12 | |
| GSE20123 | IQCB1 | 9657 | 18 | 0 | 12 | |
| GSE43470 | IQCB1 | 9657 | 20 | 0 | 23 | |
| GSE46452 | IQCB1 | 9657 | 14 | 5 | 40 | |
| GSE47630 | IQCB1 | 9657 | 16 | 5 | 19 | |
| GSE54993 | IQCB1 | 9657 | 2 | 6 | 62 | |
| GSE54994 | IQCB1 | 9657 | 30 | 4 | 19 | |
| GSE60625 | IQCB1 | 9657 | 0 | 6 | 5 | |
| GSE74703 | IQCB1 | 9657 | 16 | 0 | 20 | |
| GSE74704 | IQCB1 | 9657 | 13 | 0 | 7 | |
| TCGA | IQCB1 | 9657 | 54 | 6 | 36 |
Total number of gains: 201; Total number of losses: 32; Total Number of normals: 255.
Somatic mutations of IQCB1:
Generating mutation plots.
Highly correlated genes for IQCB1:
Showing top 20/1074 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IQCB1 | ZNF628 | 0.78089 | 4 | 0 | 4 |
| IQCB1 | SP100 | 0.770703 | 3 | 0 | 3 |
| IQCB1 | RRP36 | 0.723264 | 3 | 0 | 3 |
| IQCB1 | LINC01116 | 0.721308 | 3 | 0 | 3 |
| IQCB1 | HSPBAP1 | 0.717082 | 11 | 0 | 10 |
| IQCB1 | UBE2J2 | 0.708076 | 3 | 0 | 3 |
| IQCB1 | ATR | 0.705247 | 12 | 0 | 11 |
| IQCB1 | ZNF622 | 0.703064 | 3 | 0 | 3 |
| IQCB1 | TOPBP1 | 0.701922 | 13 | 0 | 12 |
| IQCB1 | DDX60L | 0.696636 | 3 | 0 | 3 |
| IQCB1 | SRRT | 0.690291 | 8 | 0 | 7 |
| IQCB1 | ZNRD1 | 0.690086 | 4 | 0 | 3 |
| IQCB1 | PIK3R4 | 0.688667 | 11 | 0 | 11 |
| IQCB1 | WDR5B | 0.686668 | 13 | 0 | 11 |
| IQCB1 | RRP12 | 0.683402 | 3 | 0 | 3 |
| IQCB1 | U2SURP | 0.682913 | 10 | 0 | 9 |
| IQCB1 | ACTL6A | 0.680868 | 13 | 0 | 12 |
| IQCB1 | ZFYVE27 | 0.678161 | 3 | 0 | 3 |
| IQCB1 | RBM12B | 0.678087 | 5 | 0 | 5 |
| IQCB1 | POGLUT1 | 0.677888 | 10 | 0 | 8 |
For details and further investigation, click here
