| Full name: ribosomal RNA processing 12 homolog | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 10q24.1 | ||
| Entrez ID: 23223 | HGNC ID: HGNC:29100 | Ensembl Gene: ENSG00000052749 | OMIM ID: 617723 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RRP12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RRP12 | 23223 | 216913_s_at | 0.8137 | 0.1376 | |
| GSE20347 | RRP12 | 23223 | 216913_s_at | 0.1648 | 0.2275 | |
| GSE23400 | RRP12 | 23223 | 216913_s_at | 0.1281 | 0.0186 | |
| GSE26886 | RRP12 | 23223 | 216913_s_at | 0.6983 | 0.0000 | |
| GSE29001 | RRP12 | 23223 | 216913_s_at | 0.0872 | 0.6094 | |
| GSE38129 | RRP12 | 23223 | 216913_s_at | 0.3835 | 0.0007 | |
| GSE45670 | RRP12 | 23223 | 216913_s_at | 0.4654 | 0.0031 | |
| GSE53622 | RRP12 | 23223 | 26936 | 0.1711 | 0.0643 | |
| GSE53624 | RRP12 | 23223 | 26936 | 0.3995 | 0.0000 | |
| GSE63941 | RRP12 | 23223 | 216913_s_at | 0.6311 | 0.1734 | |
| GSE77861 | RRP12 | 23223 | 216913_s_at | 0.2761 | 0.0377 | |
| GSE97050 | RRP12 | 23223 | A_23_P24192 | 0.6479 | 0.2597 | |
| SRP007169 | RRP12 | 23223 | RNAseq | 0.8607 | 0.0601 | |
| SRP008496 | RRP12 | 23223 | RNAseq | 1.0545 | 0.0134 | |
| SRP064894 | RRP12 | 23223 | RNAseq | 0.3018 | 0.2012 | |
| SRP133303 | RRP12 | 23223 | RNAseq | 0.4529 | 0.0205 | |
| SRP159526 | RRP12 | 23223 | RNAseq | 0.4988 | 0.0994 | |
| SRP193095 | RRP12 | 23223 | RNAseq | 0.6269 | 0.0001 | |
| SRP219564 | RRP12 | 23223 | RNAseq | 0.7545 | 0.1243 | |
| TCGA | RRP12 | 23223 | RNAseq | 0.1435 | 0.0075 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by RRP12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RRP12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RRP12 | 23223 | 0 | 8 | 22 | |
| GSE20123 | RRP12 | 23223 | 0 | 7 | 23 | |
| GSE43470 | RRP12 | 23223 | 0 | 7 | 36 | |
| GSE46452 | RRP12 | 23223 | 0 | 11 | 48 | |
| GSE47630 | RRP12 | 23223 | 2 | 14 | 24 | |
| GSE54993 | RRP12 | 23223 | 8 | 0 | 62 | |
| GSE54994 | RRP12 | 23223 | 2 | 10 | 41 | |
| GSE60625 | RRP12 | 23223 | 0 | 0 | 11 | |
| GSE74703 | RRP12 | 23223 | 0 | 5 | 31 | |
| GSE74704 | RRP12 | 23223 | 0 | 4 | 16 | |
| TCGA | RRP12 | 23223 | 5 | 28 | 63 |
Total number of gains: 17; Total number of losses: 94; Total Number of normals: 377.
Somatic mutations of RRP12:
Generating mutation plots.
Highly correlated genes for RRP12:
Showing top 20/523 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RRP12 | C16orf91 | 0.73685 | 3 | 0 | 3 |
| RRP12 | TMEM102 | 0.722776 | 3 | 0 | 3 |
| RRP12 | MRPL14 | 0.694568 | 4 | 0 | 4 |
| RRP12 | BUB1B | 0.692911 | 5 | 0 | 5 |
| RRP12 | NSUN6 | 0.69041 | 5 | 0 | 4 |
| RRP12 | RAB15 | 0.690237 | 3 | 0 | 3 |
| RRP12 | IQCB1 | 0.683402 | 3 | 0 | 3 |
| RRP12 | CD276 | 0.671847 | 5 | 0 | 5 |
| RRP12 | HOXD13 | 0.671609 | 4 | 0 | 4 |
| RRP12 | CDCA2 | 0.667964 | 3 | 0 | 3 |
| RRP12 | TTC9C | 0.667698 | 3 | 0 | 3 |
| RRP12 | IRX2 | 0.660971 | 5 | 0 | 4 |
| RRP12 | GPC2 | 0.66076 | 3 | 0 | 3 |
| RRP12 | E2F7 | 0.659273 | 4 | 0 | 3 |
| RRP12 | COL24A1 | 0.657527 | 3 | 0 | 3 |
| RRP12 | BEND3 | 0.656844 | 7 | 0 | 7 |
| RRP12 | MYBBP1A | 0.65324 | 12 | 0 | 10 |
| RRP12 | BCL2L12 | 0.652348 | 6 | 0 | 4 |
| RRP12 | POP7 | 0.64939 | 6 | 0 | 5 |
| RRP12 | POLR3A | 0.648764 | 7 | 0 | 5 |
For details and further investigation, click here
