| Full name: zinc finger protein 622 | Alias Symbol: MGC2485|MGC17552|ZPR9 | ||
| Type: protein-coding gene | Cytoband: 5p15.1 | ||
| Entrez ID: 90441 | HGNC ID: HGNC:30958 | Ensembl Gene: ENSG00000173545 | OMIM ID: 608694 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ZNF622:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF622 | 90441 | 225152_at | 0.2058 | 0.4319 | |
| GSE26886 | ZNF622 | 90441 | 225152_at | 0.6866 | 0.0004 | |
| GSE45670 | ZNF622 | 90441 | 225152_at | 0.2831 | 0.2118 | |
| GSE53622 | ZNF622 | 90441 | 96838 | 0.1850 | 0.0066 | |
| GSE53624 | ZNF622 | 90441 | 96838 | 0.2703 | 0.0044 | |
| GSE63941 | ZNF622 | 90441 | 225152_at | -0.5804 | 0.0842 | |
| GSE77861 | ZNF622 | 90441 | 225152_at | 0.4080 | 0.0136 | |
| GSE97050 | ZNF622 | 90441 | A_23_P156209 | 0.5318 | 0.1512 | |
| SRP007169 | ZNF622 | 90441 | RNAseq | -0.1233 | 0.8119 | |
| SRP008496 | ZNF622 | 90441 | RNAseq | -0.0042 | 0.9910 | |
| SRP064894 | ZNF622 | 90441 | RNAseq | 0.1276 | 0.5198 | |
| SRP133303 | ZNF622 | 90441 | RNAseq | 0.2651 | 0.1619 | |
| SRP159526 | ZNF622 | 90441 | RNAseq | 0.1535 | 0.6675 | |
| SRP193095 | ZNF622 | 90441 | RNAseq | 0.1470 | 0.2563 | |
| SRP219564 | ZNF622 | 90441 | RNAseq | 0.2122 | 0.4309 | |
| TCGA | ZNF622 | 90441 | RNAseq | 0.0404 | 0.5060 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF622 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF622:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF622 | 90441 | 12 | 0 | 18 | |
| GSE20123 | ZNF622 | 90441 | 12 | 0 | 18 | |
| GSE43470 | ZNF622 | 90441 | 18 | 0 | 25 | |
| GSE46452 | ZNF622 | 90441 | 6 | 22 | 31 | |
| GSE47630 | ZNF622 | 90441 | 6 | 11 | 23 | |
| GSE54993 | ZNF622 | 90441 | 5 | 5 | 60 | |
| GSE54994 | ZNF622 | 90441 | 29 | 2 | 22 | |
| GSE60625 | ZNF622 | 90441 | 0 | 0 | 11 | |
| GSE74703 | ZNF622 | 90441 | 14 | 0 | 22 | |
| GSE74704 | ZNF622 | 90441 | 11 | 0 | 9 | |
| TCGA | ZNF622 | 90441 | 59 | 3 | 34 |
Total number of gains: 172; Total number of losses: 43; Total Number of normals: 273.
Somatic mutations of ZNF622:
Generating mutation plots.
Highly correlated genes for ZNF622:
Showing top 20/595 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF622 | CDK5RAP1 | 0.729999 | 4 | 0 | 4 |
| ZNF622 | XRN2 | 0.728159 | 3 | 0 | 3 |
| ZNF622 | ORC3 | 0.719175 | 3 | 0 | 3 |
| ZNF622 | INHBB | 0.71341 | 4 | 0 | 4 |
| ZNF622 | TCHH | 0.705124 | 3 | 0 | 3 |
| ZNF622 | IQCB1 | 0.703064 | 3 | 0 | 3 |
| ZNF622 | SLC39A6 | 0.702251 | 4 | 0 | 4 |
| ZNF622 | CSTF1 | 0.698872 | 5 | 0 | 4 |
| ZNF622 | ATIC | 0.697657 | 3 | 0 | 3 |
| ZNF622 | TSN | 0.684866 | 4 | 0 | 4 |
| ZNF622 | CPT1C | 0.678254 | 3 | 0 | 3 |
| ZNF622 | ALCAM | 0.670359 | 3 | 0 | 3 |
| ZNF622 | GTF2E2 | 0.670023 | 4 | 0 | 3 |
| ZNF622 | RNF166 | 0.669906 | 3 | 0 | 3 |
| ZNF622 | PSMB3 | 0.669864 | 4 | 0 | 3 |
| ZNF622 | SPRED1 | 0.669689 | 5 | 0 | 5 |
| ZNF622 | CCNA2 | 0.669587 | 3 | 0 | 3 |
| ZNF622 | PHLDB2 | 0.666014 | 3 | 0 | 3 |
| ZNF622 | ZSCAN21 | 0.665548 | 3 | 0 | 3 |
| ZNF622 | MRGPRX3 | 0.664863 | 4 | 0 | 4 |
For details and further investigation, click here
