| Full name: WD repeat domain 5B | Alias Symbol: FLJ11287 | ||
| Type: protein-coding gene | Cytoband: 3q21.1 | ||
| Entrez ID: 54554 | HGNC ID: HGNC:17826 | Ensembl Gene: ENSG00000196981 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of WDR5B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDR5B | 54554 | 219538_at | 0.4784 | 0.2453 | |
| GSE20347 | WDR5B | 54554 | 219538_at | 0.8175 | 0.0000 | |
| GSE23400 | WDR5B | 54554 | 219538_at | 0.2557 | 0.0000 | |
| GSE26886 | WDR5B | 54554 | 219538_at | 0.6546 | 0.0009 | |
| GSE29001 | WDR5B | 54554 | 219538_at | 0.7199 | 0.0311 | |
| GSE38129 | WDR5B | 54554 | 219538_at | 0.6849 | 0.0000 | |
| GSE45670 | WDR5B | 54554 | 219538_at | 0.6708 | 0.0015 | |
| GSE53622 | WDR5B | 54554 | 27598 | 0.8078 | 0.0000 | |
| GSE53624 | WDR5B | 54554 | 27598 | 0.7660 | 0.0000 | |
| GSE63941 | WDR5B | 54554 | 219538_at | -0.0334 | 0.9444 | |
| GSE77861 | WDR5B | 54554 | 219538_at | 0.3202 | 0.2026 | |
| GSE97050 | WDR5B | 54554 | A_33_P3259548 | 0.5302 | 0.2371 | |
| SRP007169 | WDR5B | 54554 | RNAseq | 1.1118 | 0.0326 | |
| SRP008496 | WDR5B | 54554 | RNAseq | 1.4518 | 0.0000 | |
| SRP064894 | WDR5B | 54554 | RNAseq | 0.6600 | 0.0002 | |
| SRP133303 | WDR5B | 54554 | RNAseq | 0.3011 | 0.1428 | |
| SRP159526 | WDR5B | 54554 | RNAseq | 0.8472 | 0.0008 | |
| SRP193095 | WDR5B | 54554 | RNAseq | 0.4103 | 0.0001 | |
| SRP219564 | WDR5B | 54554 | RNAseq | 0.5525 | 0.0641 | |
| TCGA | WDR5B | 54554 | RNAseq | -0.0334 | 0.6713 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by WDR5B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDR5B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDR5B | 54554 | 18 | 0 | 12 | |
| GSE20123 | WDR5B | 54554 | 18 | 0 | 12 | |
| GSE43470 | WDR5B | 54554 | 20 | 0 | 23 | |
| GSE46452 | WDR5B | 54554 | 14 | 5 | 40 | |
| GSE47630 | WDR5B | 54554 | 16 | 5 | 19 | |
| GSE54993 | WDR5B | 54554 | 2 | 6 | 62 | |
| GSE54994 | WDR5B | 54554 | 30 | 4 | 19 | |
| GSE60625 | WDR5B | 54554 | 0 | 6 | 5 | |
| GSE74703 | WDR5B | 54554 | 16 | 0 | 20 | |
| GSE74704 | WDR5B | 54554 | 13 | 0 | 7 | |
| TCGA | WDR5B | 54554 | 54 | 6 | 36 |
Total number of gains: 201; Total number of losses: 32; Total Number of normals: 255.
Somatic mutations of WDR5B:
Generating mutation plots.
Highly correlated genes for WDR5B:
Showing top 20/1264 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDR5B | DUS3L | 0.72825 | 3 | 0 | 3 |
| WDR5B | MTBP | 0.72407 | 4 | 0 | 4 |
| WDR5B | LRRC58 | 0.712451 | 5 | 0 | 5 |
| WDR5B | CHKA | 0.708527 | 3 | 0 | 3 |
| WDR5B | ESPN | 0.707836 | 3 | 0 | 3 |
| WDR5B | MMS22L | 0.694616 | 3 | 0 | 3 |
| WDR5B | ANKRD23 | 0.693955 | 3 | 0 | 3 |
| WDR5B | TOPBP1 | 0.691869 | 12 | 0 | 11 |
| WDR5B | ATP2C1 | 0.690537 | 11 | 0 | 9 |
| WDR5B | IQCB1 | 0.686668 | 13 | 0 | 11 |
| WDR5B | ALG10B | 0.685876 | 3 | 0 | 3 |
| WDR5B | PIK3R4 | 0.684218 | 11 | 0 | 10 |
| WDR5B | AURKAIP1 | 0.683421 | 3 | 0 | 3 |
| WDR5B | UBE2T | 0.683044 | 6 | 0 | 6 |
| WDR5B | NAA38 | 0.681679 | 4 | 0 | 3 |
| WDR5B | SMIM8 | 0.680875 | 5 | 0 | 5 |
| WDR5B | UBE2J2 | 0.679766 | 3 | 0 | 3 |
| WDR5B | DNAJB11 | 0.679307 | 5 | 0 | 5 |
| WDR5B | PHF6 | 0.677668 | 3 | 0 | 3 |
| WDR5B | GORAB | 0.674962 | 6 | 0 | 5 |
For details and further investigation, click here
