| Full name: TBC1 domain family member 22A | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 22q13.31 | ||
| Entrez ID: 25771 | HGNC ID: HGNC:1309 | Ensembl Gene: ENSG00000054611 | OMIM ID: 616879 |
| Drug and gene relationship at DGIdb | |||
Expression of TBC1D22A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TBC1D22A | 25771 | 33778_at | 0.1456 | 0.7638 | |
| GSE20347 | TBC1D22A | 25771 | 33778_at | -0.3975 | 0.0091 | |
| GSE23400 | TBC1D22A | 25771 | 33778_at | -0.0940 | 0.0799 | |
| GSE26886 | TBC1D22A | 25771 | 33778_at | 0.2746 | 0.1187 | |
| GSE29001 | TBC1D22A | 25771 | 33778_at | -0.4914 | 0.1558 | |
| GSE38129 | TBC1D22A | 25771 | 33778_at | -0.2299 | 0.0925 | |
| GSE45670 | TBC1D22A | 25771 | 33778_at | 0.0002 | 0.9992 | |
| GSE53622 | TBC1D22A | 25771 | 18783 | -0.3622 | 0.0000 | |
| GSE53624 | TBC1D22A | 25771 | 18783 | -0.1959 | 0.0001 | |
| GSE63941 | TBC1D22A | 25771 | 33778_at | 0.0144 | 0.9798 | |
| GSE77861 | TBC1D22A | 25771 | 209650_s_at | -0.1421 | 0.5371 | |
| GSE97050 | TBC1D22A | 25771 | A_23_P109593 | 0.3154 | 0.2830 | |
| SRP007169 | TBC1D22A | 25771 | RNAseq | -0.9586 | 0.0024 | |
| SRP008496 | TBC1D22A | 25771 | RNAseq | -0.8061 | 0.0003 | |
| SRP064894 | TBC1D22A | 25771 | RNAseq | 0.1232 | 0.5559 | |
| SRP133303 | TBC1D22A | 25771 | RNAseq | -0.2742 | 0.0021 | |
| SRP159526 | TBC1D22A | 25771 | RNAseq | -0.1798 | 0.4554 | |
| SRP193095 | TBC1D22A | 25771 | RNAseq | -0.0534 | 0.6835 | |
| SRP219564 | TBC1D22A | 25771 | RNAseq | -0.0977 | 0.7550 | |
| TCGA | TBC1D22A | 25771 | RNAseq | -0.0422 | 0.4304 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TBC1D22A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TBC1D22A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TBC1D22A | 25771 | 5 | 8 | 17 | |
| GSE20123 | TBC1D22A | 25771 | 4 | 6 | 20 | |
| GSE43470 | TBC1D22A | 25771 | 2 | 6 | 35 | |
| GSE46452 | TBC1D22A | 25771 | 31 | 2 | 26 | |
| GSE47630 | TBC1D22A | 25771 | 9 | 4 | 27 | |
| GSE54993 | TBC1D22A | 25771 | 3 | 6 | 61 | |
| GSE54994 | TBC1D22A | 25771 | 11 | 7 | 35 | |
| GSE60625 | TBC1D22A | 25771 | 5 | 0 | 6 | |
| GSE74703 | TBC1D22A | 25771 | 2 | 4 | 30 | |
| GSE74704 | TBC1D22A | 25771 | 2 | 3 | 15 | |
| TCGA | TBC1D22A | 25771 | 28 | 18 | 50 |
Total number of gains: 102; Total number of losses: 64; Total Number of normals: 322.
Somatic mutations of TBC1D22A:
Generating mutation plots.
Highly correlated genes for TBC1D22A:
Showing top 20/456 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TBC1D22A | IRF2BP1 | 0.799559 | 3 | 0 | 3 |
| TBC1D22A | PUSL1 | 0.78044 | 3 | 0 | 3 |
| TBC1D22A | TSPAN17 | 0.761506 | 3 | 0 | 3 |
| TBC1D22A | ATP11A | 0.756371 | 3 | 0 | 3 |
| TBC1D22A | CIDEB | 0.754283 | 3 | 0 | 3 |
| TBC1D22A | SLC39A11 | 0.751381 | 3 | 0 | 3 |
| TBC1D22A | MUL1 | 0.744886 | 3 | 0 | 3 |
| TBC1D22A | XPNPEP1 | 0.737142 | 3 | 0 | 3 |
| TBC1D22A | PRELID1 | 0.727303 | 3 | 0 | 3 |
| TBC1D22A | SHMT2 | 0.726846 | 3 | 0 | 3 |
| TBC1D22A | ADAM11 | 0.711098 | 3 | 0 | 3 |
| TBC1D22A | MFSD3 | 0.707932 | 4 | 0 | 4 |
| TBC1D22A | ZBTB7B | 0.706945 | 3 | 0 | 3 |
| TBC1D22A | ITGB3 | 0.706818 | 3 | 0 | 3 |
| TBC1D22A | RAB35 | 0.704655 | 4 | 0 | 3 |
| TBC1D22A | MAPK11 | 0.702097 | 4 | 0 | 3 |
| TBC1D22A | ANKRD54 | 0.698589 | 3 | 0 | 3 |
| TBC1D22A | PPP1R37 | 0.696491 | 4 | 0 | 4 |
| TBC1D22A | COMTD1 | 0.694536 | 4 | 0 | 3 |
| TBC1D22A | BMP8A | 0.69309 | 3 | 0 | 3 |
For details and further investigation, click here
