| Full name: integrin subunit beta like 1 | Alias Symbol: TIED|OSCP | ||
| Type: protein-coding gene | Cytoband: 13q33.1 | ||
| Entrez ID: 9358 | HGNC ID: HGNC:6164 | Ensembl Gene: ENSG00000198542 | OMIM ID: 604234 |
| Drug and gene relationship at DGIdb | |||
Expression of ITGBL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ITGBL1 | 9358 | 214927_at | -0.7926 | 0.5291 | |
| GSE20347 | ITGBL1 | 9358 | 214927_at | 0.6461 | 0.0223 | |
| GSE23400 | ITGBL1 | 9358 | 214927_at | 0.0927 | 0.4105 | |
| GSE26886 | ITGBL1 | 9358 | 214927_at | 0.6966 | 0.0319 | |
| GSE29001 | ITGBL1 | 9358 | 214927_at | 0.2152 | 0.5358 | |
| GSE38129 | ITGBL1 | 9358 | 214927_at | 0.2899 | 0.3042 | |
| GSE45670 | ITGBL1 | 9358 | 214927_at | -1.9334 | 0.0000 | |
| GSE63941 | ITGBL1 | 9358 | 214927_at | -4.8228 | 0.0008 | |
| GSE77861 | ITGBL1 | 9358 | 214927_at | -0.0231 | 0.8976 | |
| GSE97050 | ITGBL1 | 9358 | A_33_P3418209 | -0.3027 | 0.6018 | |
| SRP007169 | ITGBL1 | 9358 | RNAseq | 3.4938 | 0.0000 | |
| SRP064894 | ITGBL1 | 9358 | RNAseq | 0.8945 | 0.0725 | |
| SRP133303 | ITGBL1 | 9358 | RNAseq | 0.9013 | 0.0117 | |
| SRP159526 | ITGBL1 | 9358 | RNAseq | 0.8817 | 0.0984 | |
| SRP219564 | ITGBL1 | 9358 | RNAseq | 0.8460 | 0.2100 | |
| TCGA | ITGBL1 | 9358 | RNAseq | -0.3926 | 0.1764 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by ITGBL1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ITGBL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ITGBL1 | 9358 | 3 | 9 | 18 | |
| GSE20123 | ITGBL1 | 9358 | 3 | 8 | 19 | |
| GSE43470 | ITGBL1 | 9358 | 4 | 12 | 27 | |
| GSE46452 | ITGBL1 | 9358 | 0 | 32 | 27 | |
| GSE47630 | ITGBL1 | 9358 | 3 | 26 | 11 | |
| GSE54993 | ITGBL1 | 9358 | 11 | 4 | 55 | |
| GSE54994 | ITGBL1 | 9358 | 6 | 10 | 37 | |
| GSE60625 | ITGBL1 | 9358 | 0 | 3 | 8 | |
| GSE74703 | ITGBL1 | 9358 | 3 | 10 | 23 | |
| GSE74704 | ITGBL1 | 9358 | 1 | 8 | 11 | |
| TCGA | ITGBL1 | 9358 | 15 | 34 | 47 |
Total number of gains: 49; Total number of losses: 156; Total Number of normals: 283.
Somatic mutations of ITGBL1:
Generating mutation plots.
Highly correlated genes for ITGBL1:
Showing top 20/481 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ITGBL1 | SHISA3 | 0.829783 | 3 | 0 | 3 |
| ITGBL1 | TBX5-AS1 | 0.78783 | 4 | 0 | 3 |
| ITGBL1 | LINC00702 | 0.772286 | 3 | 0 | 3 |
| ITGBL1 | MRVI1 | 0.771898 | 4 | 0 | 4 |
| ITGBL1 | CCDC80 | 0.769152 | 4 | 0 | 4 |
| ITGBL1 | ZNF471 | 0.763518 | 3 | 0 | 3 |
| ITGBL1 | MGARP | 0.761304 | 3 | 0 | 3 |
| ITGBL1 | LINC01279 | 0.760991 | 4 | 0 | 4 |
| ITGBL1 | MAGI2-AS3 | 0.753673 | 4 | 0 | 4 |
| ITGBL1 | S1PR1 | 0.748384 | 3 | 0 | 3 |
| ITGBL1 | RBPMS2 | 0.746773 | 3 | 0 | 3 |
| ITGBL1 | SLC4A4 | 0.734945 | 3 | 0 | 3 |
| ITGBL1 | PGR | 0.732023 | 3 | 0 | 3 |
| ITGBL1 | GALNT15 | 0.730093 | 4 | 0 | 3 |
| ITGBL1 | ABCB4 | 0.729774 | 3 | 0 | 3 |
| ITGBL1 | LINC00968 | 0.726436 | 3 | 0 | 3 |
| ITGBL1 | C8orf88 | 0.7262 | 3 | 0 | 3 |
| ITGBL1 | CYS1 | 0.720751 | 4 | 0 | 4 |
| ITGBL1 | AOX1 | 0.717606 | 3 | 0 | 3 |
| ITGBL1 | OSR1 | 0.711721 | 4 | 0 | 4 |
For details and further investigation, click here
