| Full name: synaptic vesicle glycoprotein 2B | Alias Symbol: KIAA0735|HsT19680 | ||
| Type: protein-coding gene | Cytoband: 15q26.1 | ||
| Entrez ID: 9899 | HGNC ID: HGNC:16874 | Ensembl Gene: ENSG00000185518 | OMIM ID: 185861 |
| Drug and gene relationship at DGIdb | |||
Expression of SV2B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SV2B | 9899 | 205551_at | -0.0125 | 0.9779 | |
| GSE20347 | SV2B | 9899 | 205551_at | 0.2842 | 0.0842 | |
| GSE23400 | SV2B | 9899 | 205551_at | 0.0322 | 0.5353 | |
| GSE26886 | SV2B | 9899 | 205551_at | 1.4104 | 0.0120 | |
| GSE29001 | SV2B | 9899 | 205551_at | 0.0764 | 0.7324 | |
| GSE38129 | SV2B | 9899 | 205551_at | 0.1471 | 0.5515 | |
| GSE45670 | SV2B | 9899 | 244717_x_at | 0.0496 | 0.5962 | |
| GSE53622 | SV2B | 9899 | 90496 | 0.0695 | 0.5272 | |
| GSE53624 | SV2B | 9899 | 90496 | 0.0655 | 0.4523 | |
| GSE63941 | SV2B | 9899 | 232426_at | 0.1012 | 0.6223 | |
| GSE77861 | SV2B | 9899 | 232426_at | -0.1180 | 0.2654 | |
| GSE97050 | SV2B | 9899 | A_23_P100022 | 0.1045 | 0.6187 | |
| SRP007169 | SV2B | 9899 | RNAseq | 0.7589 | 0.3639 | |
| SRP064894 | SV2B | 9899 | RNAseq | 0.2365 | 0.5414 | |
| SRP133303 | SV2B | 9899 | RNAseq | -0.2140 | 0.5491 | |
| SRP159526 | SV2B | 9899 | RNAseq | 1.8688 | 0.0118 | |
| SRP193095 | SV2B | 9899 | RNAseq | -0.1029 | 0.5651 | |
| SRP219564 | SV2B | 9899 | RNAseq | -0.0944 | 0.8634 | |
| TCGA | SV2B | 9899 | RNAseq | -0.4809 | 0.2137 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by SV2B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SV2B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SV2B | 9899 | 7 | 2 | 21 | |
| GSE20123 | SV2B | 9899 | 7 | 2 | 21 | |
| GSE43470 | SV2B | 9899 | 5 | 5 | 33 | |
| GSE46452 | SV2B | 9899 | 3 | 7 | 49 | |
| GSE47630 | SV2B | 9899 | 8 | 11 | 21 | |
| GSE54993 | SV2B | 9899 | 4 | 6 | 60 | |
| GSE54994 | SV2B | 9899 | 7 | 7 | 39 | |
| GSE60625 | SV2B | 9899 | 4 | 0 | 7 | |
| GSE74703 | SV2B | 9899 | 4 | 4 | 28 | |
| GSE74704 | SV2B | 9899 | 3 | 3 | 14 | |
| TCGA | SV2B | 9899 | 19 | 12 | 65 |
Total number of gains: 71; Total number of losses: 59; Total Number of normals: 358.
Somatic mutations of SV2B:
Generating mutation plots.
Highly correlated genes for SV2B:
Showing top 20/117 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SV2B | JAKMIP3 | 0.878428 | 3 | 0 | 3 |
| SV2B | QPRT | 0.761944 | 3 | 0 | 3 |
| SV2B | GPC3 | 0.720625 | 4 | 0 | 3 |
| SV2B | FAM110B | 0.710405 | 4 | 0 | 3 |
| SV2B | PPOX | 0.708158 | 3 | 0 | 3 |
| SV2B | AGPAT1 | 0.705884 | 4 | 0 | 4 |
| SV2B | OR1F1 | 0.704623 | 3 | 0 | 3 |
| SV2B | MCF2L | 0.699597 | 3 | 0 | 3 |
| SV2B | AVPR1B | 0.697724 | 3 | 0 | 3 |
| SV2B | TMEM163 | 0.684058 | 3 | 0 | 3 |
| SV2B | TRPM3 | 0.682716 | 3 | 0 | 3 |
| SV2B | TRAF3IP3 | 0.678163 | 3 | 0 | 3 |
| SV2B | CRYBB3 | 0.664158 | 3 | 0 | 3 |
| SV2B | USP51 | 0.661288 | 3 | 0 | 3 |
| SV2B | LRTM2 | 0.660466 | 4 | 0 | 3 |
| SV2B | TXNDC2 | 0.6554 | 4 | 0 | 3 |
| SV2B | MUC2 | 0.65438 | 4 | 0 | 3 |
| SV2B | TSPAN33 | 0.652011 | 3 | 0 | 3 |
| SV2B | MPP3 | 0.648524 | 4 | 0 | 3 |
| SV2B | MAPK15 | 0.64843 | 3 | 0 | 3 |
For details and further investigation, click here
