| Full name: jumonji domain containing 6, arginine demethylase and lysine hydroxylase | Alias Symbol: PTDSR1|KIAA0585 | ||
| Type: protein-coding gene | Cytoband: 17q25.1 | ||
| Entrez ID: 23210 | HGNC ID: HGNC:19355 | Ensembl Gene: ENSG00000070495 | OMIM ID: 604914 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of JMJD6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | JMJD6 | 23210 | 212723_at | -0.0307 | 0.9697 | |
| GSE20347 | JMJD6 | 23210 | 212723_at | 0.4146 | 0.0100 | |
| GSE23400 | JMJD6 | 23210 | 212723_at | 0.2062 | 0.0119 | |
| GSE26886 | JMJD6 | 23210 | 212723_at | 1.2827 | 0.0000 | |
| GSE29001 | JMJD6 | 23210 | 212723_at | 0.2735 | 0.3381 | |
| GSE38129 | JMJD6 | 23210 | 212723_at | 0.2958 | 0.0749 | |
| GSE45670 | JMJD6 | 23210 | 212723_at | 0.1439 | 0.6200 | |
| GSE53622 | JMJD6 | 23210 | 17619 | 0.1723 | 0.0635 | |
| GSE53624 | JMJD6 | 23210 | 17619 | 0.3592 | 0.0000 | |
| GSE63941 | JMJD6 | 23210 | 212723_at | -0.3832 | 0.3386 | |
| GSE77861 | JMJD6 | 23210 | 212723_at | 0.2955 | 0.2403 | |
| GSE97050 | JMJD6 | 23210 | A_23_P311616 | -0.0909 | 0.8073 | |
| SRP007169 | JMJD6 | 23210 | RNAseq | 1.0757 | 0.0472 | |
| SRP008496 | JMJD6 | 23210 | RNAseq | 1.5025 | 0.0016 | |
| SRP064894 | JMJD6 | 23210 | RNAseq | 0.4390 | 0.0325 | |
| SRP133303 | JMJD6 | 23210 | RNAseq | 0.7159 | 0.0001 | |
| SRP159526 | JMJD6 | 23210 | RNAseq | 0.3751 | 0.2749 | |
| SRP193095 | JMJD6 | 23210 | RNAseq | 0.6382 | 0.0000 | |
| SRP219564 | JMJD6 | 23210 | RNAseq | -0.1786 | 0.7317 | |
| TCGA | JMJD6 | 23210 | RNAseq | -0.0658 | 0.2346 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by JMJD6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of JMJD6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | JMJD6 | 23210 | 7 | 2 | 21 | |
| GSE20123 | JMJD6 | 23210 | 7 | 2 | 21 | |
| GSE43470 | JMJD6 | 23210 | 4 | 3 | 36 | |
| GSE46452 | JMJD6 | 23210 | 33 | 1 | 25 | |
| GSE47630 | JMJD6 | 23210 | 8 | 1 | 31 | |
| GSE54993 | JMJD6 | 23210 | 2 | 5 | 63 | |
| GSE54994 | JMJD6 | 23210 | 10 | 4 | 39 | |
| GSE60625 | JMJD6 | 23210 | 6 | 0 | 5 | |
| GSE74703 | JMJD6 | 23210 | 4 | 1 | 31 | |
| GSE74704 | JMJD6 | 23210 | 5 | 1 | 14 | |
| TCGA | JMJD6 | 23210 | 31 | 10 | 55 |
Total number of gains: 117; Total number of losses: 30; Total Number of normals: 341.
Somatic mutations of JMJD6:
Generating mutation plots.
Highly correlated genes for JMJD6:
Showing top 20/444 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| JMJD6 | PI16 | 0.724449 | 3 | 0 | 3 |
| JMJD6 | ABRA | 0.706326 | 3 | 0 | 3 |
| JMJD6 | NUMBL | 0.703446 | 3 | 0 | 3 |
| JMJD6 | KDM6B | 0.689521 | 3 | 0 | 3 |
| JMJD6 | NPTX1 | 0.68351 | 4 | 0 | 4 |
| JMJD6 | COL24A1 | 0.662582 | 4 | 0 | 3 |
| JMJD6 | TTC33 | 0.661408 | 3 | 0 | 3 |
| JMJD6 | KLHL25 | 0.661322 | 3 | 0 | 3 |
| JMJD6 | NFIL3 | 0.657277 | 10 | 0 | 10 |
| JMJD6 | CASKIN2 | 0.656499 | 4 | 0 | 4 |
| JMJD6 | PLIN4 | 0.655781 | 3 | 0 | 3 |
| JMJD6 | UBB | 0.647097 | 6 | 0 | 6 |
| JMJD6 | MATN4 | 0.645301 | 3 | 0 | 3 |
| JMJD6 | SGCA | 0.635891 | 4 | 0 | 3 |
| JMJD6 | PPP1R14A | 0.635679 | 3 | 0 | 3 |
| JMJD6 | ZMYND19 | 0.635636 | 3 | 0 | 3 |
| JMJD6 | FAM230C | 0.635077 | 3 | 0 | 3 |
| JMJD6 | BCORL1 | 0.634377 | 4 | 0 | 3 |
| JMJD6 | DAPK1 | 0.632757 | 3 | 0 | 3 |
| JMJD6 | PACSIN2 | 0.632542 | 6 | 0 | 5 |
For details and further investigation, click here
