| Full name: USO1 vesicle transport factor | Alias Symbol: TAP|VDP|p115 | ||
| Type: protein-coding gene | Cytoband: 4q21.1 | ||
| Entrez ID: 8615 | HGNC ID: HGNC:30904 | Ensembl Gene: ENSG00000138768 | OMIM ID: 603344 |
| Drug and gene relationship at DGIdb | |||
Expression of USO1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | USO1 | 8615 | 201832_s_at | -0.6030 | 0.0326 | |
| GSE20347 | USO1 | 8615 | 201832_s_at | -0.9090 | 0.0000 | |
| GSE23400 | USO1 | 8615 | 201832_s_at | -0.6869 | 0.0000 | |
| GSE26886 | USO1 | 8615 | 201832_s_at | -1.2007 | 0.0000 | |
| GSE29001 | USO1 | 8615 | 201832_s_at | -1.2511 | 0.0012 | |
| GSE38129 | USO1 | 8615 | 201832_s_at | -0.7021 | 0.0000 | |
| GSE45670 | USO1 | 8615 | 201832_s_at | -0.6078 | 0.0001 | |
| GSE53622 | USO1 | 8615 | 15729 | -0.6523 | 0.0000 | |
| GSE53624 | USO1 | 8615 | 15729 | -0.8303 | 0.0000 | |
| GSE63941 | USO1 | 8615 | 201832_s_at | -0.9573 | 0.0052 | |
| GSE77861 | USO1 | 8615 | 201832_s_at | -0.7985 | 0.0263 | |
| GSE97050 | USO1 | 8615 | A_23_P29855 | -0.1130 | 0.5932 | |
| SRP007169 | USO1 | 8615 | RNAseq | -0.8760 | 0.0035 | |
| SRP008496 | USO1 | 8615 | RNAseq | -0.6343 | 0.0006 | |
| SRP064894 | USO1 | 8615 | RNAseq | -1.1356 | 0.0000 | |
| SRP133303 | USO1 | 8615 | RNAseq | 0.0074 | 0.9763 | |
| SRP159526 | USO1 | 8615 | RNAseq | -1.0393 | 0.0000 | |
| SRP193095 | USO1 | 8615 | RNAseq | -0.9815 | 0.0000 | |
| SRP219564 | USO1 | 8615 | RNAseq | -0.8517 | 0.0056 | |
| TCGA | USO1 | 8615 | RNAseq | -0.1722 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by USO1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of USO1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | USO1 | 8615 | 2 | 9 | 19 | |
| GSE20123 | USO1 | 8615 | 2 | 9 | 19 | |
| GSE43470 | USO1 | 8615 | 0 | 13 | 30 | |
| GSE46452 | USO1 | 8615 | 2 | 35 | 22 | |
| GSE47630 | USO1 | 8615 | 1 | 19 | 20 | |
| GSE54993 | USO1 | 8615 | 7 | 0 | 63 | |
| GSE54994 | USO1 | 8615 | 1 | 9 | 43 | |
| GSE60625 | USO1 | 8615 | 0 | 0 | 11 | |
| GSE74703 | USO1 | 8615 | 0 | 11 | 25 | |
| GSE74704 | USO1 | 8615 | 2 | 5 | 13 | |
| TCGA | USO1 | 8615 | 17 | 30 | 49 |
Total number of gains: 34; Total number of losses: 140; Total Number of normals: 314.
Somatic mutations of USO1:
Generating mutation plots.
Highly correlated genes for USO1:
Showing top 20/1566 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| USO1 | GGA3 | 0.806494 | 3 | 0 | 3 |
| USO1 | HDHD2 | 0.771892 | 5 | 0 | 5 |
| USO1 | NAGK | 0.770617 | 11 | 0 | 11 |
| USO1 | ZACN | 0.761817 | 3 | 0 | 3 |
| USO1 | HPGD | 0.759614 | 11 | 0 | 11 |
| USO1 | FAM214A | 0.75961 | 6 | 0 | 6 |
| USO1 | KAT2B | 0.755856 | 12 | 0 | 11 |
| USO1 | FAM3D | 0.755473 | 6 | 0 | 6 |
| USO1 | C4orf3 | 0.754643 | 7 | 0 | 7 |
| USO1 | KRT78 | 0.754516 | 6 | 0 | 6 |
| USO1 | SH3BGRL2 | 0.75031 | 7 | 0 | 7 |
| USO1 | CGNL1 | 0.750176 | 7 | 0 | 7 |
| USO1 | ARPC1A | 0.749877 | 3 | 0 | 3 |
| USO1 | FCER1A | 0.749553 | 10 | 0 | 10 |
| USO1 | BRK1 | 0.749145 | 7 | 0 | 7 |
| USO1 | BBIP1 | 0.748434 | 7 | 0 | 7 |
| USO1 | KIAA0232 | 0.747943 | 10 | 0 | 10 |
| USO1 | KCTD6 | 0.74747 | 7 | 0 | 7 |
| USO1 | VSIG2 | 0.747143 | 6 | 0 | 6 |
| USO1 | ATP6V1C2 | 0.745123 | 4 | 0 | 4 |
For details and further investigation, click here
