| Full name: F-box and leucine rich repeat protein 17 | Alias Symbol: DKFZP434C1715|Fbx13|Fbl17 | ||
| Type: protein-coding gene | Cytoband: 5q21.3 | ||
| Entrez ID: 64839 | HGNC ID: HGNC:13615 | Ensembl Gene: ENSG00000145743 | OMIM ID: 609083 |
| Drug and gene relationship at DGIdb | |||
Expression of FBXL17:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBXL17 | 64839 | 227203_at | -0.4099 | 0.1860 | |
| GSE26886 | FBXL17 | 64839 | 227203_at | -0.4350 | 0.2003 | |
| GSE45670 | FBXL17 | 64839 | 227203_at | -0.6167 | 0.0089 | |
| GSE53622 | FBXL17 | 64839 | 3793 | -0.9198 | 0.0000 | |
| GSE53624 | FBXL17 | 64839 | 20338 | -1.2003 | 0.0000 | |
| GSE63941 | FBXL17 | 64839 | 227203_at | -1.6545 | 0.0044 | |
| GSE77861 | FBXL17 | 64839 | 227203_at | -0.7917 | 0.0091 | |
| GSE97050 | FBXL17 | 64839 | A_33_P3314436 | -0.3766 | 0.1601 | |
| SRP007169 | FBXL17 | 64839 | RNAseq | -2.4864 | 0.0000 | |
| SRP008496 | FBXL17 | 64839 | RNAseq | -1.9598 | 0.0000 | |
| SRP064894 | FBXL17 | 64839 | RNAseq | -0.7559 | 0.0000 | |
| SRP133303 | FBXL17 | 64839 | RNAseq | -0.3539 | 0.0916 | |
| SRP159526 | FBXL17 | 64839 | RNAseq | -0.8869 | 0.0260 | |
| SRP193095 | FBXL17 | 64839 | RNAseq | -0.9413 | 0.0000 | |
| SRP219564 | FBXL17 | 64839 | RNAseq | -0.8350 | 0.0178 | |
| TCGA | FBXL17 | 64839 | RNAseq | -0.3150 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by FBXL17 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBXL17:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBXL17 | 64839 | 1 | 13 | 16 | |
| GSE20123 | FBXL17 | 64839 | 1 | 13 | 16 | |
| GSE43470 | FBXL17 | 64839 | 3 | 9 | 31 | |
| GSE46452 | FBXL17 | 64839 | 0 | 28 | 31 | |
| GSE47630 | FBXL17 | 64839 | 0 | 21 | 19 | |
| GSE54993 | FBXL17 | 64839 | 9 | 1 | 60 | |
| GSE54994 | FBXL17 | 64839 | 1 | 17 | 35 | |
| GSE60625 | FBXL17 | 64839 | 0 | 0 | 11 | |
| GSE74703 | FBXL17 | 64839 | 2 | 7 | 27 | |
| GSE74704 | FBXL17 | 64839 | 1 | 7 | 12 | |
| TCGA | FBXL17 | 64839 | 3 | 44 | 49 |
Total number of gains: 21; Total number of losses: 160; Total Number of normals: 307.
Somatic mutations of FBXL17:
Generating mutation plots.
Highly correlated genes for FBXL17:
Showing top 20/1244 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBXL17 | MAP1A | 0.778434 | 3 | 0 | 3 |
| FBXL17 | DUSP22 | 0.772263 | 5 | 0 | 5 |
| FBXL17 | MACROD2 | 0.769194 | 3 | 0 | 3 |
| FBXL17 | DPY19L3 | 0.745388 | 3 | 0 | 3 |
| FBXL17 | FAM204A | 0.742354 | 3 | 0 | 3 |
| FBXL17 | LRRK2 | 0.742333 | 6 | 0 | 6 |
| FBXL17 | ACAA1 | 0.741538 | 6 | 0 | 5 |
| FBXL17 | RCAN2 | 0.739754 | 4 | 0 | 4 |
| FBXL17 | DMXL1 | 0.736286 | 8 | 0 | 8 |
| FBXL17 | KLC1 | 0.735044 | 3 | 0 | 3 |
| FBXL17 | FOXN3 | 0.729358 | 3 | 0 | 3 |
| FBXL17 | PRKAR2A | 0.727581 | 4 | 0 | 4 |
| FBXL17 | S1PR1 | 0.721544 | 4 | 0 | 4 |
| FBXL17 | BTAF1 | 0.721221 | 3 | 0 | 3 |
| FBXL17 | GPBP1 | 0.720816 | 4 | 0 | 4 |
| FBXL17 | KBTBD3 | 0.719959 | 3 | 0 | 3 |
| FBXL17 | IK | 0.718273 | 7 | 0 | 7 |
| FBXL17 | FDX1 | 0.716835 | 3 | 0 | 3 |
| FBXL17 | C6orf62 | 0.716816 | 4 | 0 | 4 |
| FBXL17 | RERG | 0.714612 | 3 | 0 | 3 |
For details and further investigation, click here
