RHO

 

Full name: rhodopsin Alias Symbol: OPN2|CSNBAD1
Type: protein-coding gene Cytoband: 3q22.1
Entrez ID: 6010 HGNC ID: HGNC:10012 Ensembl Gene: ENSG00000163914 OMIM ID: 180380
Drug and gene relationship at DGIdb

 

Expression of RHO:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RHO 6010 206455_s_at 0.0095 0.9771
GSE20347 RHO 6010 206455_s_at 0.0409 0.6109
GSE23400 RHO 6010 206455_s_at -0.0987 0.0024
GSE26886 RHO 6010 206455_s_at -0.0562 0.6770
GSE29001 RHO 6010 206454_s_at -0.1877 0.1614
GSE38129 RHO 6010 206455_s_at -0.0219 0.8410
GSE45670 RHO 6010 206455_s_at -0.0361 0.7077
GSE63941 RHO 6010 206455_s_at 0.4631 0.0008
GSE77861 RHO 6010 206455_s_at 0.0215 0.8414
GSE97050 RHO 6010 A_23_P407472 0.1428 0.5400
TCGA RHO 6010 RNAseq 1.0484 0.4434

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by RHO expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of RHO:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RHO 6010 17 0 13
GSE20123 RHO 6010 17 0 13
GSE43470 RHO 6010 19 0 24
GSE46452 RHO 6010 14 5 40
GSE47630 RHO 6010 18 3 19
GSE54993 RHO 6010 2 8 60
GSE54994 RHO 6010 32 3 18
GSE60625 RHO 6010 0 6 5
GSE74703 RHO 6010 17 0 19
GSE74704 RHO 6010 13 0 7
TCGA RHO 6010 58 5 33

Total number of gains: 207; Total number of losses: 30; Total Number of normals: 251.  


 

Somatic mutations of RHO:

 

Generating mutation plots.

 

Highly correlated genes for RHO:

 

Showing top 20/929 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RHOIKBKG0.755244303
RHOKHDRBS20.699836505
RHOTAAR20.6986303
RHOSPRR40.698116303
RHOCACNA1G-AS10.692235303
RHOMYOG0.684745606
RHOBMP150.675716605
RHOHTR1D0.675584404
RHODSCAM0.673763908
RHOCGA0.672458505
RHOMC2R0.66876807
RHOHPCA0.66471504
RHOODF10.662956606
RHOFSTL40.661836504
RHOHSD3B10.661197504
RHOADAM300.659116504
RHOEPOR0.658307807
RHOKLK140.658062403
RHOTRPV50.654781606
RHOSLC28A10.654578706

For details and further investigation, click here