| Full name: synuclein gamma | Alias Symbol: BCSG1|SR|persyn | ||
| Type: protein-coding gene | Cytoband: 10q23.2 | ||
| Entrez ID: 6623 | HGNC ID: HGNC:11141 | Ensembl Gene: ENSG00000173267 | OMIM ID: 602998 |
| Drug and gene relationship at DGIdb | |||
Expression of SNCG:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNCG | 6623 | 209877_at | -0.1999 | 0.6051 | |
| GSE20347 | SNCG | 6623 | 209877_at | -0.5107 | 0.0000 | |
| GSE23400 | SNCG | 6623 | 209877_at | -0.4037 | 0.0000 | |
| GSE26886 | SNCG | 6623 | 209877_at | 0.2602 | 0.0455 | |
| GSE29001 | SNCG | 6623 | 208584_at | -0.0334 | 0.8440 | |
| GSE38129 | SNCG | 6623 | 209877_at | -0.7376 | 0.0000 | |
| GSE45670 | SNCG | 6623 | 209877_at | -0.2409 | 0.0224 | |
| GSE63941 | SNCG | 6623 | 209877_at | 1.2540 | 0.0846 | |
| GSE77861 | SNCG | 6623 | 209877_at | -0.2848 | 0.0705 | |
| GSE97050 | SNCG | 6623 | A_23_P251293 | -0.3921 | 0.3739 | |
| SRP064894 | SNCG | 6623 | RNAseq | -1.3753 | 0.0110 | |
| SRP133303 | SNCG | 6623 | RNAseq | -2.4122 | 0.0000 | |
| SRP159526 | SNCG | 6623 | RNAseq | -2.3065 | 0.0002 | |
| SRP193095 | SNCG | 6623 | RNAseq | -1.7841 | 0.0000 | |
| SRP219564 | SNCG | 6623 | RNAseq | -2.0809 | 0.0010 | |
| TCGA | SNCG | 6623 | RNAseq | -0.3303 | 0.1833 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by SNCG expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of SNCG:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNCG | 6623 | 1 | 7 | 22 | |
| GSE20123 | SNCG | 6623 | 1 | 6 | 23 | |
| GSE43470 | SNCG | 6623 | 0 | 7 | 36 | |
| GSE46452 | SNCG | 6623 | 0 | 11 | 48 | |
| GSE47630 | SNCG | 6623 | 2 | 14 | 24 | |
| GSE54993 | SNCG | 6623 | 7 | 0 | 63 | |
| GSE54994 | SNCG | 6623 | 1 | 11 | 41 | |
| GSE60625 | SNCG | 6623 | 0 | 0 | 11 | |
| GSE74703 | SNCG | 6623 | 0 | 5 | 31 | |
| GSE74704 | SNCG | 6623 | 0 | 4 | 16 | |
| TCGA | SNCG | 6623 | 7 | 27 | 62 |
Total number of gains: 19; Total number of losses: 92; Total Number of normals: 377.
Somatic mutations of SNCG:
Generating mutation plots.
Highly correlated genes for SNCG:
Showing top 20/608 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNCG | KCNK2 | 0.763427 | 3 | 0 | 3 |
| SNCG | ZFAND2B | 0.755811 | 4 | 0 | 4 |
| SNCG | PHYHD1 | 0.751711 | 3 | 0 | 3 |
| SNCG | SSNA1 | 0.727341 | 3 | 0 | 3 |
| SNCG | LIPF | 0.716587 | 3 | 0 | 3 |
| SNCG | C16orf70 | 0.712483 | 3 | 0 | 3 |
| SNCG | PROX1 | 0.70097 | 3 | 0 | 3 |
| SNCG | BLOC1S1 | 0.697212 | 8 | 0 | 7 |
| SNCG | ZNF83 | 0.697122 | 3 | 0 | 3 |
| SNCG | CNPPD1 | 0.695308 | 7 | 0 | 6 |
| SNCG | CRABP2 | 0.694932 | 4 | 0 | 4 |
| SNCG | PPP1R1B | 0.689862 | 3 | 0 | 3 |
| SNCG | FAM166A | 0.689103 | 3 | 0 | 3 |
| SNCG | ANKRD18A | 0.686753 | 3 | 0 | 3 |
| SNCG | SLC24A3 | 0.684808 | 5 | 0 | 5 |
| SNCG | CAPN3 | 0.684524 | 3 | 0 | 3 |
| SNCG | RGS14 | 0.68434 | 6 | 0 | 6 |
| SNCG | ULK3 | 0.681291 | 3 | 0 | 3 |
| SNCG | COL11A2 | 0.678269 | 4 | 0 | 4 |
| SNCG | CABLES1 | 0.6775 | 3 | 0 | 3 |
For details and further investigation, click here
