| Full name: potassium voltage-gated channel interacting protein 3 | Alias Symbol: DREAM|KCHIP3 | ||
| Type: protein-coding gene | Cytoband: 2q11.1 | ||
| Entrez ID: 30818 | HGNC ID: HGNC:15523 | Ensembl Gene: ENSG00000115041 | OMIM ID: 604662 |
| Drug and gene relationship at DGIdb | |||
Expression of KCNIP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KCNIP3 | 30818 | 228269_x_at | 0.1022 | 0.8018 | |
| GSE26886 | KCNIP3 | 30818 | 228269_x_at | 0.2940 | 0.0128 | |
| GSE45670 | KCNIP3 | 30818 | 228269_x_at | -0.0992 | 0.4197 | |
| GSE53622 | KCNIP3 | 30818 | 62547 | -0.5359 | 0.0156 | |
| GSE53624 | KCNIP3 | 30818 | 62547 | 0.1951 | 0.1354 | |
| GSE63941 | KCNIP3 | 30818 | 228269_x_at | 0.2096 | 0.3464 | |
| GSE77861 | KCNIP3 | 30818 | 228269_x_at | -0.0745 | 0.5320 | |
| GSE97050 | KCNIP3 | 30818 | A_23_P356004 | -0.2399 | 0.5512 | |
| SRP064894 | KCNIP3 | 30818 | RNAseq | 0.7500 | 0.0673 | |
| SRP133303 | KCNIP3 | 30818 | RNAseq | 0.7121 | 0.0901 | |
| SRP159526 | KCNIP3 | 30818 | RNAseq | 1.4492 | 0.0285 | |
| SRP219564 | KCNIP3 | 30818 | RNAseq | 0.7761 | 0.3890 | |
| TCGA | KCNIP3 | 30818 | RNAseq | -0.3932 | 0.0106 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by KCNIP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KCNIP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KCNIP3 | 30818 | 7 | 2 | 21 | |
| GSE20123 | KCNIP3 | 30818 | 7 | 2 | 21 | |
| GSE43470 | KCNIP3 | 30818 | 3 | 2 | 38 | |
| GSE46452 | KCNIP3 | 30818 | 2 | 3 | 54 | |
| GSE47630 | KCNIP3 | 30818 | 7 | 0 | 33 | |
| GSE54993 | KCNIP3 | 30818 | 0 | 6 | 64 | |
| GSE54994 | KCNIP3 | 30818 | 11 | 0 | 42 | |
| GSE60625 | KCNIP3 | 30818 | 0 | 3 | 8 | |
| GSE74703 | KCNIP3 | 30818 | 3 | 1 | 32 | |
| GSE74704 | KCNIP3 | 30818 | 4 | 1 | 15 | |
| TCGA | KCNIP3 | 30818 | 35 | 4 | 57 |
Total number of gains: 79; Total number of losses: 24; Total Number of normals: 385.
Somatic mutations of KCNIP3:
Generating mutation plots.
Highly correlated genes for KCNIP3:
Showing top 20/59 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KCNIP3 | PDLIM7 | 0.726208 | 3 | 0 | 3 |
| KCNIP3 | MRPS21 | 0.641795 | 3 | 0 | 3 |
| KCNIP3 | HMX1 | 0.617465 | 3 | 0 | 3 |
| KCNIP3 | SLC35F1 | 0.617359 | 3 | 0 | 3 |
| KCNIP3 | DDX24 | 0.610496 | 3 | 0 | 3 |
| KCNIP3 | CHD5 | 0.60762 | 3 | 0 | 3 |
| KCNIP3 | ADAMTS10 | 0.604488 | 3 | 0 | 3 |
| KCNIP3 | FADS2 | 0.60208 | 3 | 0 | 3 |
| KCNIP3 | ZNF316 | 0.595317 | 4 | 0 | 3 |
| KCNIP3 | PRR12 | 0.595265 | 3 | 0 | 3 |
| KCNIP3 | ANKS3 | 0.593667 | 4 | 0 | 3 |
| KCNIP3 | HDAC10 | 0.587497 | 3 | 0 | 3 |
| KCNIP3 | RILPL1 | 0.585268 | 4 | 0 | 3 |
| KCNIP3 | JUND | 0.584841 | 4 | 0 | 3 |
| KCNIP3 | PLCL1 | 0.582939 | 3 | 0 | 3 |
| KCNIP3 | LINC00886 | 0.582493 | 3 | 0 | 3 |
| KCNIP3 | CCDC92 | 0.581913 | 4 | 0 | 3 |
| KCNIP3 | IL34 | 0.575239 | 3 | 0 | 3 |
| KCNIP3 | STX1A | 0.574215 | 3 | 0 | 3 |
| KCNIP3 | ZNF503 | 0.567656 | 4 | 0 | 3 |
For details and further investigation, click here
