| Full name: actin binding LIM protein family member 2 | Alias Symbol: KIAA1808 | ||
| Type: protein-coding gene | Cytoband: 4p16.1 | ||
| Entrez ID: 84448 | HGNC ID: HGNC:19195 | Ensembl Gene: ENSG00000163995 | OMIM ID: 612544 |
| Drug and gene relationship at DGIdb | |||
ABLIM2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04360 | Axon guidance |
Expression of ABLIM2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABLIM2 | 84448 | 228132_at | -0.1275 | 0.8889 | |
| GSE26886 | ABLIM2 | 84448 | 228132_at | -1.6365 | 0.0000 | |
| GSE45670 | ABLIM2 | 84448 | 228132_at | -0.2178 | 0.4623 | |
| GSE53622 | ABLIM2 | 84448 | 59806 | -1.2198 | 0.0000 | |
| GSE53624 | ABLIM2 | 84448 | 59806 | -1.3743 | 0.0000 | |
| GSE63941 | ABLIM2 | 84448 | 236087_at | -0.0815 | 0.6386 | |
| GSE77861 | ABLIM2 | 84448 | 236087_at | -0.2303 | 0.0777 | |
| GSE97050 | ABLIM2 | 84448 | A_33_P3337134 | -0.3466 | 0.2032 | |
| SRP007169 | ABLIM2 | 84448 | RNAseq | -2.1774 | 0.0013 | |
| SRP008496 | ABLIM2 | 84448 | RNAseq | -2.5005 | 0.0000 | |
| SRP064894 | ABLIM2 | 84448 | RNAseq | -1.0878 | 0.0000 | |
| SRP133303 | ABLIM2 | 84448 | RNAseq | -1.2139 | 0.0001 | |
| SRP159526 | ABLIM2 | 84448 | RNAseq | -2.0776 | 0.0000 | |
| SRP193095 | ABLIM2 | 84448 | RNAseq | -0.9335 | 0.0011 | |
| SRP219564 | ABLIM2 | 84448 | RNAseq | -0.5231 | 0.4282 | |
| TCGA | ABLIM2 | 84448 | RNAseq | 0.1243 | 0.4750 |
Upregulated datasets: 0; Downregulated datasets: 8.
Survival by ABLIM2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABLIM2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABLIM2 | 84448 | 0 | 18 | 12 | |
| GSE20123 | ABLIM2 | 84448 | 0 | 18 | 12 | |
| GSE43470 | ABLIM2 | 84448 | 0 | 17 | 26 | |
| GSE46452 | ABLIM2 | 84448 | 1 | 36 | 22 | |
| GSE47630 | ABLIM2 | 84448 | 1 | 19 | 20 | |
| GSE54993 | ABLIM2 | 84448 | 10 | 0 | 60 | |
| GSE54994 | ABLIM2 | 84448 | 3 | 12 | 38 | |
| GSE60625 | ABLIM2 | 84448 | 0 | 0 | 11 | |
| GSE74703 | ABLIM2 | 84448 | 0 | 13 | 23 | |
| GSE74704 | ABLIM2 | 84448 | 0 | 10 | 10 | |
| TCGA | ABLIM2 | 84448 | 8 | 47 | 41 |
Total number of gains: 23; Total number of losses: 190; Total Number of normals: 275.
Somatic mutations of ABLIM2:
Generating mutation plots.
Highly correlated genes for ABLIM2:
Showing top 20/1108 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABLIM2 | NDUFA10 | 0.771363 | 3 | 0 | 3 |
| ABLIM2 | CDNF | 0.770306 | 3 | 0 | 3 |
| ABLIM2 | UGP2 | 0.763903 | 3 | 0 | 3 |
| ABLIM2 | HEMK1 | 0.762388 | 3 | 0 | 3 |
| ABLIM2 | EPG5 | 0.761842 | 3 | 0 | 3 |
| ABLIM2 | DDI2 | 0.749403 | 3 | 0 | 3 |
| ABLIM2 | NDST1 | 0.744707 | 7 | 0 | 6 |
| ABLIM2 | P2RX7 | 0.742474 | 3 | 0 | 3 |
| ABLIM2 | ANKRD44 | 0.737268 | 3 | 0 | 3 |
| ABLIM2 | DLG2 | 0.736713 | 5 | 0 | 5 |
| ABLIM2 | KCTD10 | 0.736655 | 3 | 0 | 3 |
| ABLIM2 | TRIM23 | 0.735874 | 3 | 0 | 3 |
| ABLIM2 | COPZ1 | 0.735731 | 3 | 0 | 3 |
| ABLIM2 | PPP1R2 | 0.730238 | 3 | 0 | 3 |
| ABLIM2 | PAQR7 | 0.729337 | 6 | 0 | 6 |
| ABLIM2 | KIF1C | 0.724133 | 6 | 0 | 6 |
| ABLIM2 | RMND5B | 0.723437 | 6 | 0 | 6 |
| ABLIM2 | RNF10 | 0.721376 | 6 | 0 | 6 |
| ABLIM2 | UCHL5 | 0.720998 | 3 | 0 | 3 |
| ABLIM2 | POLN | 0.716308 | 3 | 0 | 3 |
For details and further investigation, click here
