| Full name: lysine demethylase 2B | Alias Symbol: PCCX2|CXXC2|Fbl10|JHDM1B | ||
| Type: protein-coding gene | Cytoband: 12q24.31 | ||
| Entrez ID: 84678 | HGNC ID: HGNC:13610 | Ensembl Gene: ENSG00000089094 | OMIM ID: 609078 |
| Drug and gene relationship at DGIdb | |||
Expression of KDM2B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KDM2B | 84678 | 226215_s_at | 0.3007 | 0.6054 | |
| GSE26886 | KDM2B | 84678 | 226215_s_at | -0.2561 | 0.1875 | |
| GSE45670 | KDM2B | 84678 | 226215_s_at | -0.1569 | 0.3406 | |
| GSE53622 | KDM2B | 84678 | 19235 | -0.3398 | 0.0000 | |
| GSE53624 | KDM2B | 84678 | 19235 | -0.3176 | 0.0000 | |
| GSE63941 | KDM2B | 84678 | 226215_s_at | 0.0135 | 0.9731 | |
| GSE77861 | KDM2B | 84678 | 226215_s_at | -0.4108 | 0.0178 | |
| GSE97050 | KDM2B | 84678 | A_33_P3529859 | -0.1149 | 0.6250 | |
| SRP007169 | KDM2B | 84678 | RNAseq | -0.7435 | 0.0870 | |
| SRP008496 | KDM2B | 84678 | RNAseq | -0.6591 | 0.0191 | |
| SRP064894 | KDM2B | 84678 | RNAseq | -0.4003 | 0.0023 | |
| SRP133303 | KDM2B | 84678 | RNAseq | -0.3621 | 0.0083 | |
| SRP159526 | KDM2B | 84678 | RNAseq | 0.0649 | 0.7793 | |
| SRP193095 | KDM2B | 84678 | RNAseq | -0.0659 | 0.6023 | |
| SRP219564 | KDM2B | 84678 | RNAseq | -0.3542 | 0.2897 | |
| TCGA | KDM2B | 84678 | RNAseq | 0.1684 | 0.0008 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KDM2B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KDM2B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KDM2B | 84678 | 5 | 4 | 21 | |
| GSE20123 | KDM2B | 84678 | 5 | 4 | 21 | |
| GSE43470 | KDM2B | 84678 | 2 | 2 | 39 | |
| GSE46452 | KDM2B | 84678 | 9 | 1 | 49 | |
| GSE47630 | KDM2B | 84678 | 9 | 3 | 28 | |
| GSE54993 | KDM2B | 84678 | 0 | 5 | 65 | |
| GSE54994 | KDM2B | 84678 | 6 | 7 | 40 | |
| GSE60625 | KDM2B | 84678 | 0 | 0 | 11 | |
| GSE74703 | KDM2B | 84678 | 2 | 1 | 33 | |
| GSE74704 | KDM2B | 84678 | 4 | 2 | 14 | |
| TCGA | KDM2B | 84678 | 22 | 10 | 64 |
Total number of gains: 64; Total number of losses: 39; Total Number of normals: 385.
Somatic mutations of KDM2B:
Generating mutation plots.
Highly correlated genes for KDM2B:
Showing top 20/485 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KDM2B | RAP1GDS1 | 0.900137 | 3 | 0 | 3 |
| KDM2B | LRP11 | 0.828442 | 3 | 0 | 3 |
| KDM2B | UTP3 | 0.778265 | 3 | 0 | 3 |
| KDM2B | MDH2 | 0.752528 | 3 | 0 | 3 |
| KDM2B | C6orf120 | 0.744178 | 3 | 0 | 3 |
| KDM2B | LCMT1 | 0.737278 | 3 | 0 | 3 |
| KDM2B | NAT1 | 0.733051 | 3 | 0 | 3 |
| KDM2B | ACAA1 | 0.730302 | 3 | 0 | 3 |
| KDM2B | TRMT10A | 0.722687 | 3 | 0 | 3 |
| KDM2B | BIRC6 | 0.722511 | 3 | 0 | 3 |
| KDM2B | ALG14 | 0.721935 | 4 | 0 | 3 |
| KDM2B | ZNF83 | 0.721341 | 3 | 0 | 3 |
| KDM2B | MPHOSPH9 | 0.72005 | 3 | 0 | 3 |
| KDM2B | ZDHHC5 | 0.718801 | 3 | 0 | 3 |
| KDM2B | RWDD2B | 0.718127 | 3 | 0 | 3 |
| KDM2B | RECQL5 | 0.7165 | 3 | 0 | 3 |
| KDM2B | FAM53B | 0.714797 | 3 | 0 | 3 |
| KDM2B | SPIN4 | 0.712995 | 3 | 0 | 3 |
| KDM2B | ZNF354C | 0.712719 | 3 | 0 | 3 |
| KDM2B | PDZD8 | 0.710353 | 3 | 0 | 3 |
For details and further investigation, click here
