| Full name: tRNA methyltransferase 10A | Alias Symbol: MGC27034|TRM10 | ||
| Type: protein-coding gene | Cytoband: 4q23 | ||
| Entrez ID: 93587 | HGNC ID: HGNC:28403 | Ensembl Gene: ENSG00000145331 | OMIM ID: 616013 |
| Drug and gene relationship at DGIdb | |||
Expression of TRMT10A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRMT10A | 93587 | 230243_at | 0.1061 | 0.9394 | |
| GSE26886 | TRMT10A | 93587 | 242442_x_at | -1.2811 | 0.0010 | |
| GSE45670 | TRMT10A | 93587 | 230243_at | -0.3411 | 0.0609 | |
| GSE53622 | TRMT10A | 93587 | 53720 | -1.2248 | 0.0000 | |
| GSE53624 | TRMT10A | 93587 | 53720 | -0.9146 | 0.0000 | |
| GSE63941 | TRMT10A | 93587 | 230243_at | -0.5290 | 0.4622 | |
| GSE77861 | TRMT10A | 93587 | 230243_at | -0.2515 | 0.0484 | |
| SRP007169 | TRMT10A | 93587 | RNAseq | 0.1652 | 0.7712 | |
| SRP008496 | TRMT10A | 93587 | RNAseq | -0.1135 | 0.7490 | |
| SRP064894 | TRMT10A | 93587 | RNAseq | -0.2245 | 0.3657 | |
| SRP133303 | TRMT10A | 93587 | RNAseq | -0.1191 | 0.4648 | |
| SRP159526 | TRMT10A | 93587 | RNAseq | -0.1875 | 0.6244 | |
| SRP193095 | TRMT10A | 93587 | RNAseq | -0.5297 | 0.0004 | |
| SRP219564 | TRMT10A | 93587 | RNAseq | -0.4783 | 0.1262 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by TRMT10A expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of TRMT10A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRMT10A | 93587 | 0 | 12 | 18 | |
| GSE20123 | TRMT10A | 93587 | 0 | 12 | 18 | |
| GSE43470 | TRMT10A | 93587 | 0 | 13 | 30 | |
| GSE46452 | TRMT10A | 93587 | 1 | 36 | 22 | |
| GSE47630 | TRMT10A | 93587 | 0 | 20 | 20 | |
| GSE54993 | TRMT10A | 93587 | 9 | 0 | 61 | |
| GSE54994 | TRMT10A | 93587 | 1 | 11 | 41 | |
| GSE60625 | TRMT10A | 93587 | 0 | 3 | 8 | |
| GSE74703 | TRMT10A | 93587 | 0 | 11 | 25 | |
| GSE74704 | TRMT10A | 93587 | 0 | 6 | 14 | |
| TCGA | TRMT10A | 93587 | 8 | 40 | 48 |
Total number of gains: 19; Total number of losses: 164; Total Number of normals: 305.
Somatic mutations of TRMT10A:
Generating mutation plots.
Highly correlated genes for TRMT10A:
Showing top 20/687 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRMT10A | KDM2B | 0.722687 | 3 | 0 | 3 |
| TRMT10A | SP1 | 0.708405 | 4 | 0 | 4 |
| TRMT10A | CNOT11 | 0.707744 | 3 | 0 | 3 |
| TRMT10A | CTTNBP2 | 0.700926 | 5 | 0 | 5 |
| TRMT10A | NANS | 0.699022 | 3 | 0 | 3 |
| TRMT10A | ECHS1 | 0.691837 | 5 | 0 | 5 |
| TRMT10A | GMDS | 0.688386 | 6 | 0 | 6 |
| TRMT10A | TP53I3 | 0.687335 | 5 | 0 | 5 |
| TRMT10A | PANK1 | 0.681492 | 5 | 0 | 4 |
| TRMT10A | VARS2 | 0.679775 | 3 | 0 | 3 |
| TRMT10A | ALDH9A1 | 0.672269 | 5 | 0 | 5 |
| TRMT10A | ZNF416 | 0.668456 | 5 | 0 | 5 |
| TRMT10A | MPP7 | 0.667682 | 5 | 0 | 5 |
| TRMT10A | PTN | 0.667451 | 3 | 0 | 3 |
| TRMT10A | GYS2 | 0.666679 | 5 | 0 | 5 |
| TRMT10A | SAMD5 | 0.666044 | 6 | 0 | 5 |
| TRMT10A | TBC1D22B | 0.661983 | 4 | 0 | 3 |
| TRMT10A | FBXO34 | 0.661917 | 6 | 0 | 5 |
| TRMT10A | EPB41L3 | 0.65903 | 5 | 0 | 4 |
| TRMT10A | CRISP3 | 0.658593 | 5 | 0 | 5 |
For details and further investigation, click here
