| Full name: zinc finger DHHC-type containing 5 | Alias Symbol: KIAA1748|ZNF375|DHHC5 | ||
| Type: protein-coding gene | Cytoband: 11q12.1 | ||
| Entrez ID: 25921 | HGNC ID: HGNC:18472 | Ensembl Gene: ENSG00000156599 | OMIM ID: 614586 |
| Drug and gene relationship at DGIdb | |||
Expression of ZDHHC5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZDHHC5 | 25921 | 224858_at | -0.0970 | 0.8708 | |
| GSE26886 | ZDHHC5 | 25921 | 224858_at | -0.6054 | 0.0030 | |
| GSE45670 | ZDHHC5 | 25921 | 224858_at | -0.0698 | 0.6887 | |
| GSE53622 | ZDHHC5 | 25921 | 15068 | -0.5154 | 0.0000 | |
| GSE53624 | ZDHHC5 | 25921 | 15068 | -0.5715 | 0.0000 | |
| GSE63941 | ZDHHC5 | 25921 | 224858_at | 0.1262 | 0.7891 | |
| GSE77861 | ZDHHC5 | 25921 | 224858_at | -0.1132 | 0.3686 | |
| GSE97050 | ZDHHC5 | 25921 | A_23_P98532 | -0.0322 | 0.9294 | |
| SRP007169 | ZDHHC5 | 25921 | RNAseq | -0.2998 | 0.3471 | |
| SRP008496 | ZDHHC5 | 25921 | RNAseq | -0.3799 | 0.1018 | |
| SRP064894 | ZDHHC5 | 25921 | RNAseq | -0.7580 | 0.0000 | |
| SRP133303 | ZDHHC5 | 25921 | RNAseq | -0.3553 | 0.0537 | |
| SRP159526 | ZDHHC5 | 25921 | RNAseq | -0.5481 | 0.0273 | |
| SRP193095 | ZDHHC5 | 25921 | RNAseq | -0.5646 | 0.0000 | |
| SRP219564 | ZDHHC5 | 25921 | RNAseq | -0.8852 | 0.0194 | |
| TCGA | ZDHHC5 | 25921 | RNAseq | 0.0706 | 0.1085 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZDHHC5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZDHHC5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZDHHC5 | 25921 | 2 | 3 | 25 | |
| GSE20123 | ZDHHC5 | 25921 | 2 | 3 | 25 | |
| GSE43470 | ZDHHC5 | 25921 | 1 | 5 | 37 | |
| GSE46452 | ZDHHC5 | 25921 | 9 | 4 | 46 | |
| GSE47630 | ZDHHC5 | 25921 | 3 | 8 | 29 | |
| GSE54993 | ZDHHC5 | 25921 | 3 | 0 | 67 | |
| GSE54994 | ZDHHC5 | 25921 | 5 | 6 | 42 | |
| GSE60625 | ZDHHC5 | 25921 | 0 | 3 | 8 | |
| GSE74703 | ZDHHC5 | 25921 | 1 | 3 | 32 | |
| GSE74704 | ZDHHC5 | 25921 | 2 | 3 | 15 | |
| TCGA | ZDHHC5 | 25921 | 14 | 10 | 72 |
Total number of gains: 42; Total number of losses: 48; Total Number of normals: 398.
Somatic mutations of ZDHHC5:
Generating mutation plots.
Highly correlated genes for ZDHHC5:
Showing top 20/1146 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZDHHC5 | UBE2A | 0.813304 | 3 | 0 | 3 |
| ZDHHC5 | TMEM147 | 0.780305 | 3 | 0 | 3 |
| ZDHHC5 | MED8 | 0.764052 | 4 | 0 | 4 |
| ZDHHC5 | ORMDL2 | 0.761586 | 3 | 0 | 3 |
| ZDHHC5 | TAX1BP3 | 0.755213 | 3 | 0 | 3 |
| ZDHHC5 | GPR157 | 0.752778 | 4 | 0 | 4 |
| ZDHHC5 | DDI2 | 0.751899 | 3 | 0 | 3 |
| ZDHHC5 | PPP1R13L | 0.748959 | 4 | 0 | 4 |
| ZDHHC5 | DAPP1 | 0.744641 | 5 | 0 | 5 |
| ZDHHC5 | UBL5 | 0.738696 | 3 | 0 | 3 |
| ZDHHC5 | ATP6V0C | 0.735778 | 3 | 0 | 3 |
| ZDHHC5 | HDHD2 | 0.735687 | 4 | 0 | 4 |
| ZDHHC5 | ZNF416 | 0.735158 | 4 | 0 | 4 |
| ZDHHC5 | TM9SF3 | 0.732813 | 3 | 0 | 3 |
| ZDHHC5 | RAPGEFL1 | 0.731135 | 6 | 0 | 6 |
| ZDHHC5 | NIPAL1 | 0.729467 | 3 | 0 | 3 |
| ZDHHC5 | PXMP2 | 0.728823 | 3 | 0 | 3 |
| ZDHHC5 | C1orf56 | 0.728425 | 4 | 0 | 3 |
| ZDHHC5 | GLYR1 | 0.726958 | 3 | 0 | 3 |
| ZDHHC5 | IMPDH2 | 0.724787 | 3 | 0 | 3 |
For details and further investigation, click here
