| Full name: dymeclin | Alias Symbol: FLJ20071|DMC|SMC | ||
| Type: protein-coding gene | Cytoband: 18q21.1 | ||
| Entrez ID: 54808 | HGNC ID: HGNC:21317 | Ensembl Gene: ENSG00000141627 | OMIM ID: 607461 |
| Drug and gene relationship at DGIdb | |||
Expression of DYM:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DYM | 54808 | 223171_at | -0.3606 | 0.3529 | |
| GSE20347 | DYM | 54808 | 220774_at | -0.0907 | 0.3954 | |
| GSE23400 | DYM | 54808 | 220774_at | -0.0492 | 0.0907 | |
| GSE26886 | DYM | 54808 | 223171_at | -0.6290 | 0.0067 | |
| GSE29001 | DYM | 54808 | 220774_at | 0.0317 | 0.8724 | |
| GSE38129 | DYM | 54808 | 220774_at | -0.1301 | 0.3077 | |
| GSE45670 | DYM | 54808 | 223171_at | -0.4196 | 0.0021 | |
| GSE53622 | DYM | 54808 | 31435 | -0.5797 | 0.0000 | |
| GSE53624 | DYM | 54808 | 31435 | -0.4903 | 0.0000 | |
| GSE63941 | DYM | 54808 | 223171_at | -0.6902 | 0.1229 | |
| GSE77861 | DYM | 54808 | 223171_at | -0.4129 | 0.2064 | |
| GSE97050 | DYM | 54808 | A_23_P170518 | -0.4985 | 0.1616 | |
| SRP007169 | DYM | 54808 | RNAseq | -1.1037 | 0.0016 | |
| SRP008496 | DYM | 54808 | RNAseq | -0.1399 | 0.7217 | |
| SRP064894 | DYM | 54808 | RNAseq | -0.2884 | 0.0818 | |
| SRP133303 | DYM | 54808 | RNAseq | -0.4237 | 0.0126 | |
| SRP159526 | DYM | 54808 | RNAseq | -0.3462 | 0.2063 | |
| SRP193095 | DYM | 54808 | RNAseq | -0.3440 | 0.0003 | |
| SRP219564 | DYM | 54808 | RNAseq | -0.6375 | 0.1316 | |
| TCGA | DYM | 54808 | RNAseq | -0.0970 | 0.0699 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by DYM expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DYM:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DYM | 54808 | 1 | 9 | 20 | |
| GSE20123 | DYM | 54808 | 1 | 9 | 20 | |
| GSE43470 | DYM | 54808 | 0 | 5 | 38 | |
| GSE46452 | DYM | 54808 | 1 | 26 | 32 | |
| GSE47630 | DYM | 54808 | 5 | 20 | 15 | |
| GSE54993 | DYM | 54808 | 9 | 0 | 61 | |
| GSE54994 | DYM | 54808 | 1 | 17 | 35 | |
| GSE60625 | DYM | 54808 | 0 | 4 | 7 | |
| GSE74703 | DYM | 54808 | 0 | 4 | 32 | |
| GSE74704 | DYM | 54808 | 0 | 6 | 14 | |
| TCGA | DYM | 54808 | 12 | 43 | 41 |
Total number of gains: 30; Total number of losses: 143; Total Number of normals: 315.
Somatic mutations of DYM:
Generating mutation plots.
Highly correlated genes for DYM:
Showing top 20/817 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DYM | HDHD2 | 0.794117 | 6 | 0 | 6 |
| DYM | C3orf70 | 0.757947 | 3 | 0 | 3 |
| DYM | KDM4B | 0.718517 | 3 | 0 | 3 |
| DYM | C6orf62 | 0.713632 | 3 | 0 | 3 |
| DYM | CCDC159 | 0.711211 | 3 | 0 | 3 |
| DYM | EPDR1 | 0.710864 | 3 | 0 | 3 |
| DYM | C5orf24 | 0.710706 | 3 | 0 | 3 |
| DYM | FAM120AOS | 0.704768 | 3 | 0 | 3 |
| DYM | MLLT3 | 0.703163 | 4 | 0 | 3 |
| DYM | ST6GALNAC6 | 0.701454 | 4 | 0 | 3 |
| DYM | UBR2 | 0.69975 | 4 | 0 | 4 |
| DYM | CCNI | 0.69489 | 7 | 0 | 7 |
| DYM | ARHGEF9 | 0.692526 | 5 | 0 | 4 |
| DYM | ACSL1 | 0.691819 | 4 | 0 | 4 |
| DYM | GGA3 | 0.690979 | 4 | 0 | 4 |
| DYM | NAA30 | 0.68854 | 3 | 0 | 3 |
| DYM | SYTL4 | 0.687927 | 3 | 0 | 3 |
| DYM | KLHL9 | 0.687382 | 5 | 0 | 4 |
| DYM | CRBN | 0.685879 | 5 | 0 | 4 |
| DYM | PRKCH | 0.68561 | 3 | 0 | 3 |
For details and further investigation, click here
