| Full name: GABA type A receptor-associated protein | Alias Symbol: MM46|ATG8A | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 11337 | HGNC ID: HGNC:4067 | Ensembl Gene: ENSG00000170296 | OMIM ID: 605125 |
Screen Evidence:
| |||
GABARAP involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04068 | FoxO signaling pathway |
Expression of GABARAP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GABARAP | 11337 | 200645_at | -0.1187 | 0.7385 | |
| GSE20347 | GABARAP | 11337 | 200645_at | -0.3284 | 0.0107 | |
| GSE23400 | GABARAP | 11337 | 200645_at | -0.1376 | 0.0096 | |
| GSE26886 | GABARAP | 11337 | 200645_at | -0.3363 | 0.0110 | |
| GSE29001 | GABARAP | 11337 | 200645_at | -0.5804 | 0.1232 | |
| GSE38129 | GABARAP | 11337 | 200645_at | -0.2626 | 0.0413 | |
| GSE45670 | GABARAP | 11337 | 200645_at | -0.3272 | 0.0069 | |
| GSE63941 | GABARAP | 11337 | 200645_at | -0.4585 | 0.2114 | |
| GSE77861 | GABARAP | 11337 | 200645_at | -0.1838 | 0.3889 | |
| GSE97050 | GABARAP | 11337 | A_23_P27075 | -0.4502 | 0.1949 | |
| SRP007169 | GABARAP | 11337 | RNAseq | -1.5857 | 0.0001 | |
| SRP008496 | GABARAP | 11337 | RNAseq | -1.3890 | 0.0000 | |
| SRP064894 | GABARAP | 11337 | RNAseq | 0.0093 | 0.9792 | |
| SRP133303 | GABARAP | 11337 | RNAseq | -0.4586 | 0.0008 | |
| SRP159526 | GABARAP | 11337 | RNAseq | -0.4259 | 0.0031 | |
| SRP193095 | GABARAP | 11337 | RNAseq | -0.7652 | 0.0000 | |
| SRP219564 | GABARAP | 11337 | RNAseq | -0.1323 | 0.6506 | |
| TCGA | GABARAP | 11337 | RNAseq | -0.1372 | 0.0015 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by GABARAP expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of GABARAP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GABARAP | 11337 | 4 | 2 | 24 | |
| GSE20123 | GABARAP | 11337 | 4 | 3 | 23 | |
| GSE43470 | GABARAP | 11337 | 1 | 4 | 38 | |
| GSE46452 | GABARAP | 11337 | 34 | 1 | 24 | |
| GSE47630 | GABARAP | 11337 | 7 | 1 | 32 | |
| GSE54993 | GABARAP | 11337 | 4 | 3 | 63 | |
| GSE54994 | GABARAP | 11337 | 5 | 8 | 40 | |
| GSE60625 | GABARAP | 11337 | 4 | 0 | 7 | |
| GSE74703 | GABARAP | 11337 | 1 | 2 | 33 | |
| GSE74704 | GABARAP | 11337 | 2 | 1 | 17 | |
| TCGA | GABARAP | 11337 | 17 | 21 | 58 |
Total number of gains: 83; Total number of losses: 46; Total Number of normals: 359.
Somatic mutations of GABARAP:
Generating mutation plots.
Highly correlated genes for GABARAP:
Showing top 20/230 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GABARAP | BCAS3 | 0.702142 | 3 | 0 | 3 |
| GABARAP | UFSP2 | 0.682059 | 5 | 0 | 5 |
| GABARAP | CCDC28A | 0.682041 | 4 | 0 | 4 |
| GABARAP | EIF3F | 0.65965 | 3 | 0 | 3 |
| GABARAP | RPS18 | 0.659247 | 4 | 0 | 3 |
| GABARAP | MGP | 0.656168 | 3 | 0 | 3 |
| GABARAP | P4HB | 0.653803 | 4 | 0 | 3 |
| GABARAP | DCLK1 | 0.647725 | 4 | 0 | 4 |
| GABARAP | NATD1 | 0.643317 | 3 | 0 | 3 |
| GABARAP | APOD | 0.640792 | 3 | 0 | 3 |
| GABARAP | TMEM222 | 0.635981 | 3 | 0 | 3 |
| GABARAP | MAN2B2 | 0.634821 | 3 | 0 | 3 |
| GABARAP | RPS5 | 0.634691 | 4 | 0 | 4 |
| GABARAP | SNX17 | 0.633058 | 4 | 0 | 3 |
| GABARAP | DAPK1 | 0.63127 | 3 | 0 | 3 |
| GABARAP | MOB2 | 0.628374 | 3 | 0 | 3 |
| GABARAP | KDM4C | 0.624683 | 4 | 0 | 4 |
| GABARAP | UBXN1 | 0.622981 | 4 | 0 | 3 |
| GABARAP | GNAI2 | 0.622589 | 3 | 0 | 3 |
| GABARAP | RAI2 | 0.621983 | 4 | 0 | 4 |
For details and further investigation, click here
