| Full name: methyltransferase like 2B | Alias Symbol: METL|FLJ11350 | ||
| Type: protein-coding gene | Cytoband: 7q32.1 | ||
| Entrez ID: 55798 | HGNC ID: HGNC:18272 | Ensembl Gene: ENSG00000165055 | OMIM ID: 607846 |
| Drug and gene relationship at DGIdb | |||
Expression of METTL2B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | METTL2B | 55798 | 222276_at | 0.4330 | 0.2260 | |
| GSE20347 | METTL2B | 55798 | 222276_at | 0.0181 | 0.8990 | |
| GSE23400 | METTL2B | 55798 | 222276_at | 0.0229 | 0.6457 | |
| GSE26886 | METTL2B | 55798 | 222276_at | -0.1004 | 0.6091 | |
| GSE29001 | METTL2B | 55798 | 222276_at | 0.0768 | 0.8319 | |
| GSE38129 | METTL2B | 55798 | 222276_at | 0.0615 | 0.6424 | |
| GSE45670 | METTL2B | 55798 | 222276_at | 0.3405 | 0.0758 | |
| GSE53622 | METTL2B | 55798 | 19917 | 0.1075 | 0.1958 | |
| GSE53624 | METTL2B | 55798 | 19917 | 0.0965 | 0.1096 | |
| GSE63941 | METTL2B | 55798 | 222276_at | -0.7031 | 0.0464 | |
| GSE77861 | METTL2B | 55798 | 222276_at | 0.0569 | 0.6959 | |
| GSE97050 | METTL2B | 55798 | A_23_P59836 | -0.0248 | 0.9213 | |
| SRP007169 | METTL2B | 55798 | RNAseq | 0.4369 | 0.2443 | |
| SRP008496 | METTL2B | 55798 | RNAseq | 0.3895 | 0.0856 | |
| SRP064894 | METTL2B | 55798 | RNAseq | 0.1948 | 0.3015 | |
| SRP133303 | METTL2B | 55798 | RNAseq | 0.2579 | 0.0388 | |
| SRP159526 | METTL2B | 55798 | RNAseq | 0.2442 | 0.4548 | |
| SRP193095 | METTL2B | 55798 | RNAseq | -0.1449 | 0.1311 | |
| SRP219564 | METTL2B | 55798 | RNAseq | -0.2741 | 0.3839 | |
| TCGA | METTL2B | 55798 | RNAseq | -0.0237 | 0.6938 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by METTL2B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of METTL2B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | METTL2B | 55798 | 8 | 1 | 21 | |
| GSE20123 | METTL2B | 55798 | 8 | 2 | 20 | |
| GSE43470 | METTL2B | 55798 | 2 | 3 | 38 | |
| GSE46452 | METTL2B | 55798 | 7 | 2 | 50 | |
| GSE47630 | METTL2B | 55798 | 7 | 4 | 29 | |
| GSE54993 | METTL2B | 55798 | 3 | 5 | 62 | |
| GSE54994 | METTL2B | 55798 | 8 | 7 | 38 | |
| GSE60625 | METTL2B | 55798 | 0 | 0 | 11 | |
| GSE74703 | METTL2B | 55798 | 2 | 3 | 31 | |
| GSE74704 | METTL2B | 55798 | 4 | 2 | 14 | |
| TCGA | METTL2B | 55798 | 28 | 22 | 46 |
Total number of gains: 77; Total number of losses: 51; Total Number of normals: 360.
Somatic mutations of METTL2B:
Generating mutation plots.
Highly correlated genes for METTL2B:
Showing top 20/37 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| METTL2B | DCPS | 0.785398 | 3 | 0 | 3 |
| METTL2B | RBM28 | 0.745104 | 3 | 0 | 3 |
| METTL2B | ARL8A | 0.684506 | 3 | 0 | 3 |
| METTL2B | CELSR3 | 0.654766 | 3 | 0 | 3 |
| METTL2B | ZNF511 | 0.652856 | 3 | 0 | 3 |
| METTL2B | SMKR1 | 0.645605 | 3 | 0 | 3 |
| METTL2B | PUS1 | 0.64556 | 4 | 0 | 4 |
| METTL2B | CCDC142 | 0.626286 | 3 | 0 | 3 |
| METTL2B | RUSC1 | 0.618188 | 3 | 0 | 3 |
| METTL2B | PDCD11 | 0.613393 | 5 | 0 | 3 |
| METTL2B | EME2 | 0.591961 | 3 | 0 | 3 |
| METTL2B | IQCH | 0.585216 | 4 | 0 | 3 |
| METTL2B | TMUB1 | 0.582455 | 3 | 0 | 3 |
| METTL2B | KDM4C | 0.579678 | 3 | 0 | 3 |
| METTL2B | IL12RB2 | 0.576279 | 3 | 0 | 3 |
| METTL2B | RBM25 | 0.574568 | 5 | 0 | 3 |
| METTL2B | NPM3 | 0.574083 | 4 | 0 | 4 |
| METTL2B | ENTPD6 | 0.568251 | 4 | 0 | 3 |
| METTL2B | ARMC7 | 0.565392 | 4 | 0 | 3 |
| METTL2B | FBRSL1 | 0.564969 | 4 | 0 | 3 |
For details and further investigation, click here
