| Full name: nuclear transcription factor, X-box binding 1 | Alias Symbol: NFX2|MGC20369|Tex42|TEG-42 | ||
| Type: protein-coding gene | Cytoband: 9p12 | ||
| Entrez ID: 4799 | HGNC ID: HGNC:7803 | Ensembl Gene: ENSG00000086102 | OMIM ID: 603255 |
| Drug and gene relationship at DGIdb | |||
Expression of NFX1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NFX1 | 4799 | 1553103_at | -0.7759 | 0.0937 | |
| GSE20347 | NFX1 | 4799 | 202584_at | -0.3277 | 0.0137 | |
| GSE23400 | NFX1 | 4799 | 202584_at | -0.0871 | 0.0837 | |
| GSE26886 | NFX1 | 4799 | 1553103_at | 0.8128 | 0.0004 | |
| GSE29001 | NFX1 | 4799 | 202584_at | -0.1049 | 0.7024 | |
| GSE38129 | NFX1 | 4799 | 202584_at | -0.3283 | 0.0018 | |
| GSE45670 | NFX1 | 4799 | 1553103_at | -0.1254 | 0.4774 | |
| GSE53622 | NFX1 | 4799 | 33395 | -0.0074 | 0.9267 | |
| GSE53624 | NFX1 | 4799 | 54658 | -0.2376 | 0.0000 | |
| GSE63941 | NFX1 | 4799 | 1553103_at | 0.3638 | 0.4514 | |
| GSE77861 | NFX1 | 4799 | 1553103_at | -0.1617 | 0.6540 | |
| GSE97050 | NFX1 | 4799 | A_23_P94683 | 0.0528 | 0.8139 | |
| SRP007169 | NFX1 | 4799 | RNAseq | 0.2496 | 0.5690 | |
| SRP008496 | NFX1 | 4799 | RNAseq | 0.4411 | 0.0914 | |
| SRP064894 | NFX1 | 4799 | RNAseq | -0.1949 | 0.0606 | |
| SRP133303 | NFX1 | 4799 | RNAseq | -0.1561 | 0.0856 | |
| SRP159526 | NFX1 | 4799 | RNAseq | -0.7051 | 0.0025 | |
| SRP193095 | NFX1 | 4799 | RNAseq | -0.1335 | 0.1212 | |
| SRP219564 | NFX1 | 4799 | RNAseq | 0.0518 | 0.8824 | |
| TCGA | NFX1 | 4799 | RNAseq | -0.1079 | 0.0297 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NFX1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NFX1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NFX1 | 4799 | 3 | 13 | 14 | |
| GSE20123 | NFX1 | 4799 | 3 | 13 | 14 | |
| GSE43470 | NFX1 | 4799 | 3 | 10 | 30 | |
| GSE46452 | NFX1 | 4799 | 7 | 15 | 37 | |
| GSE47630 | NFX1 | 4799 | 1 | 21 | 18 | |
| GSE54993 | NFX1 | 4799 | 6 | 0 | 64 | |
| GSE54994 | NFX1 | 4799 | 7 | 11 | 35 | |
| GSE60625 | NFX1 | 4799 | 0 | 0 | 11 | |
| GSE74703 | NFX1 | 4799 | 2 | 7 | 27 | |
| GSE74704 | NFX1 | 4799 | 0 | 10 | 10 | |
| TCGA | NFX1 | 4799 | 16 | 44 | 36 |
Total number of gains: 48; Total number of losses: 144; Total Number of normals: 296.
Somatic mutations of NFX1:
Generating mutation plots.
Highly correlated genes for NFX1:
Showing top 20/24 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NFX1 | CRBN | 0.660163 | 3 | 0 | 3 |
| NFX1 | CEP95 | 0.641363 | 3 | 0 | 3 |
| NFX1 | KDM4C | 0.613089 | 4 | 0 | 4 |
| NFX1 | ING2 | 0.608223 | 4 | 0 | 3 |
| NFX1 | SECISBP2 | 0.596055 | 6 | 0 | 4 |
| NFX1 | SATB1 | 0.5909 | 3 | 0 | 3 |
| NFX1 | LZTFL1 | 0.587586 | 4 | 0 | 3 |
| NFX1 | TAF9B | 0.587027 | 4 | 0 | 3 |
| NFX1 | UBR2 | 0.580037 | 4 | 0 | 3 |
| NFX1 | SPICE1 | 0.565541 | 4 | 0 | 3 |
| NFX1 | GPBP1 | 0.55542 | 3 | 0 | 3 |
| NFX1 | ATF6 | 0.545026 | 5 | 0 | 3 |
| NFX1 | TFAP2B | 0.540688 | 4 | 0 | 3 |
| NFX1 | DCAF10 | 0.527827 | 10 | 0 | 6 |
| NFX1 | MPHOSPH8 | 0.519516 | 5 | 0 | 3 |
| NFX1 | SEC22B | 0.518184 | 5 | 0 | 3 |
| NFX1 | BTAF1 | 0.516866 | 7 | 0 | 3 |
| NFX1 | SMARCA2 | 0.515941 | 7 | 0 | 4 |
| NFX1 | LTN1 | 0.514071 | 6 | 0 | 4 |
| NFX1 | UBAP2 | 0.508441 | 8 | 0 | 3 |
For details and further investigation, click here
