| Full name: kizuna centrosomal protein | Alias Symbol: HT013 | ||
| Type: protein-coding gene | Cytoband: 20p11.23 | ||
| Entrez ID: 55857 | HGNC ID: HGNC:15865 | Ensembl Gene: ENSG00000088970 | OMIM ID: 615757 |
| Drug and gene relationship at DGIdb | |||
Expression of KIZ:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KIZ | 55857 | 228291_s_at | 0.7104 | 0.1463 | |
| GSE20347 | KIZ | 55857 | 219961_s_at | 0.4083 | 0.0837 | |
| GSE23400 | KIZ | 55857 | 219961_s_at | -0.0151 | 0.9049 | |
| GSE26886 | KIZ | 55857 | 228291_s_at | 1.0905 | 0.0007 | |
| GSE29001 | KIZ | 55857 | 219961_s_at | 0.5438 | 0.1400 | |
| GSE38129 | KIZ | 55857 | 219961_s_at | 0.1767 | 0.4663 | |
| GSE45670 | KIZ | 55857 | 228291_s_at | 0.1882 | 0.6166 | |
| GSE53622 | KIZ | 55857 | 147822 | 0.4471 | 0.0023 | |
| GSE53624 | KIZ | 55857 | 147822 | 0.5806 | 0.0000 | |
| GSE63941 | KIZ | 55857 | 228291_s_at | 0.0613 | 0.9296 | |
| GSE77861 | KIZ | 55857 | 228291_s_at | 0.2845 | 0.3305 | |
| SRP007169 | KIZ | 55857 | RNAseq | 0.1049 | 0.8167 | |
| SRP008496 | KIZ | 55857 | RNAseq | 0.4247 | 0.3152 | |
| SRP064894 | KIZ | 55857 | RNAseq | 0.7535 | 0.0073 | |
| SRP133303 | KIZ | 55857 | RNAseq | 0.8014 | 0.0103 | |
| SRP159526 | KIZ | 55857 | RNAseq | 0.3549 | 0.1876 | |
| SRP193095 | KIZ | 55857 | RNAseq | 0.2190 | 0.2186 | |
| SRP219564 | KIZ | 55857 | RNAseq | 0.2398 | 0.5055 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by KIZ expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of KIZ:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KIZ | 55857 | 13 | 1 | 16 | |
| GSE20123 | KIZ | 55857 | 13 | 1 | 16 | |
| GSE43470 | KIZ | 55857 | 11 | 1 | 31 | |
| GSE46452 | KIZ | 55857 | 27 | 1 | 31 | |
| GSE47630 | KIZ | 55857 | 17 | 4 | 19 | |
| GSE54993 | KIZ | 55857 | 0 | 15 | 55 | |
| GSE54994 | KIZ | 55857 | 27 | 2 | 24 | |
| GSE60625 | KIZ | 55857 | 0 | 0 | 11 | |
| GSE74703 | KIZ | 55857 | 8 | 1 | 27 | |
| GSE74704 | KIZ | 55857 | 7 | 1 | 12 |
Total number of gains: 123; Total number of losses: 27; Total Number of normals: 242.
Somatic mutations of KIZ:
Generating mutation plots.
Highly correlated genes for KIZ:
Showing top 20/134 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KIZ | C12orf65 | 0.658628 | 4 | 0 | 3 |
| KIZ | SHROOM1 | 0.635984 | 3 | 0 | 3 |
| KIZ | KREMEN2 | 0.630288 | 3 | 0 | 3 |
| KIZ | IFT43 | 0.626386 | 4 | 0 | 3 |
| KIZ | MAK16 | 0.619979 | 4 | 0 | 4 |
| KIZ | GPR153 | 0.618397 | 4 | 0 | 3 |
| KIZ | GLIS2 | 0.618339 | 4 | 0 | 3 |
| KIZ | LAMA5 | 0.617912 | 3 | 0 | 3 |
| KIZ | HSPBAP1 | 0.610733 | 4 | 0 | 3 |
| KIZ | TTLL5 | 0.610667 | 3 | 0 | 3 |
| KIZ | DCBLD2 | 0.609661 | 6 | 0 | 4 |
| KIZ | IQCB1 | 0.607451 | 3 | 0 | 3 |
| KIZ | TMEM184B | 0.599711 | 4 | 0 | 3 |
| KIZ | PLEKHA3 | 0.594339 | 3 | 0 | 3 |
| KIZ | ATF2 | 0.587804 | 4 | 0 | 3 |
| KIZ | SEMA3C | 0.583135 | 6 | 0 | 4 |
| KIZ | LURAP1L | 0.582481 | 3 | 0 | 3 |
| KIZ | TNFRSF10B | 0.582336 | 5 | 0 | 4 |
| KIZ | FMNL2 | 0.57907 | 5 | 0 | 3 |
| KIZ | GNPDA1 | 0.577623 | 5 | 0 | 3 |
For details and further investigation, click here
