| Full name: G protein-coupled receptor 153 | Alias Symbol: PGR1 | ||
| Type: protein-coding gene | Cytoband: 1p36.31 | ||
| Entrez ID: 387509 | HGNC ID: HGNC:23618 | Ensembl Gene: ENSG00000158292 | OMIM ID: 614269 |
| Drug and gene relationship at DGIdb | |||
Expression of GPR153:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPR153 | 387509 | 64942_at | 0.7087 | 0.0829 | |
| GSE20347 | GPR153 | 387509 | 64942_at | 0.5346 | 0.0013 | |
| GSE23400 | GPR153 | 387509 | 64942_at | 0.2788 | 0.0001 | |
| GSE26886 | GPR153 | 387509 | 64942_at | 0.6830 | 0.0004 | |
| GSE29001 | GPR153 | 387509 | 64942_at | 0.7032 | 0.0155 | |
| GSE38129 | GPR153 | 387509 | 64942_at | 0.3052 | 0.0251 | |
| GSE45670 | GPR153 | 387509 | 64942_at | 0.5950 | 0.0044 | |
| GSE53622 | GPR153 | 387509 | 18233 | 0.3651 | 0.0007 | |
| GSE53624 | GPR153 | 387509 | 18233 | 0.2213 | 0.0745 | |
| GSE63941 | GPR153 | 387509 | 64942_at | 0.0705 | 0.8325 | |
| GSE77861 | GPR153 | 387509 | 64942_at | 0.4351 | 0.0586 | |
| GSE97050 | GPR153 | 387509 | A_33_P3302586 | 0.6746 | 0.1139 | |
| SRP007169 | GPR153 | 387509 | RNAseq | 1.6354 | 0.0101 | |
| SRP008496 | GPR153 | 387509 | RNAseq | 1.4247 | 0.0020 | |
| SRP064894 | GPR153 | 387509 | RNAseq | 1.2397 | 0.0000 | |
| SRP133303 | GPR153 | 387509 | RNAseq | 0.9453 | 0.0001 | |
| SRP159526 | GPR153 | 387509 | RNAseq | 0.2278 | 0.6155 | |
| SRP193095 | GPR153 | 387509 | RNAseq | 1.3354 | 0.0000 | |
| SRP219564 | GPR153 | 387509 | RNAseq | 0.7116 | 0.1304 | |
| TCGA | GPR153 | 387509 | RNAseq | 0.3085 | 0.0049 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by GPR153 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPR153:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPR153 | 387509 | 3 | 6 | 21 | |
| GSE20123 | GPR153 | 387509 | 3 | 5 | 22 | |
| GSE43470 | GPR153 | 387509 | 6 | 5 | 32 | |
| GSE46452 | GPR153 | 387509 | 7 | 1 | 51 | |
| GSE47630 | GPR153 | 387509 | 8 | 4 | 28 | |
| GSE54993 | GPR153 | 387509 | 3 | 2 | 65 | |
| GSE54994 | GPR153 | 387509 | 14 | 3 | 36 | |
| GSE60625 | GPR153 | 387509 | 0 | 0 | 11 | |
| GSE74703 | GPR153 | 387509 | 5 | 3 | 28 | |
| GSE74704 | GPR153 | 387509 | 3 | 0 | 17 | |
| TCGA | GPR153 | 387509 | 12 | 22 | 62 |
Total number of gains: 64; Total number of losses: 51; Total Number of normals: 373.
Somatic mutations of GPR153:
Generating mutation plots.
Highly correlated genes for GPR153:
Showing top 20/1302 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPR153 | CCM2 | 0.81719 | 5 | 0 | 5 |
| GPR153 | CD14 | 0.804487 | 3 | 0 | 3 |
| GPR153 | NEDD1 | 0.798425 | 4 | 0 | 4 |
| GPR153 | UTP23 | 0.788148 | 3 | 0 | 3 |
| GPR153 | RNF4 | 0.785303 | 3 | 0 | 3 |
| GPR153 | CTU2 | 0.78201 | 3 | 0 | 3 |
| GPR153 | DRAP1 | 0.78199 | 3 | 0 | 3 |
| GPR153 | MICALCL | 0.778857 | 4 | 0 | 4 |
| GPR153 | TYMS | 0.777679 | 4 | 0 | 4 |
| GPR153 | NUP35 | 0.775788 | 3 | 0 | 3 |
| GPR153 | POLR2J | 0.772669 | 3 | 0 | 3 |
| GPR153 | MRPS5 | 0.768958 | 3 | 0 | 3 |
| GPR153 | FAM126A | 0.764724 | 3 | 0 | 3 |
| GPR153 | RIT2 | 0.761995 | 3 | 0 | 3 |
| GPR153 | CPNE8 | 0.761507 | 4 | 0 | 4 |
| GPR153 | HSPB11 | 0.759265 | 4 | 0 | 4 |
| GPR153 | WDR89 | 0.758331 | 3 | 0 | 3 |
| GPR153 | ITGA3 | 0.755192 | 8 | 0 | 7 |
| GPR153 | PSMG3 | 0.753766 | 5 | 0 | 5 |
| GPR153 | CDCA2 | 0.749466 | 4 | 0 | 4 |
For details and further investigation, click here
