| Full name: Kruppel like factor 8 | Alias Symbol: BKLF3|ZNF741|DXS741 | ||
| Type: protein-coding gene | Cytoband: Xp11.21 | ||
| Entrez ID: 11279 | HGNC ID: HGNC:6351 | Ensembl Gene: ENSG00000102349 | OMIM ID: 300286 |
| Drug and gene relationship at DGIdb | |||
Expression of KLF8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KLF8 | 11279 | 230986_at | -1.8846 | 0.0923 | |
| GSE20347 | KLF8 | 11279 | 219930_at | -0.9383 | 0.0000 | |
| GSE23400 | KLF8 | 11279 | 219930_at | -0.3820 | 0.0000 | |
| GSE26886 | KLF8 | 11279 | 230986_at | -2.9767 | 0.0000 | |
| GSE29001 | KLF8 | 11279 | 219930_at | -1.5682 | 0.0000 | |
| GSE38129 | KLF8 | 11279 | 219930_at | -0.8046 | 0.0000 | |
| GSE45670 | KLF8 | 11279 | 230986_at | -1.1664 | 0.0105 | |
| GSE53622 | KLF8 | 11279 | 149266 | -1.6748 | 0.0000 | |
| GSE53624 | KLF8 | 11279 | 149266 | -2.0691 | 0.0000 | |
| GSE63941 | KLF8 | 11279 | 230986_at | -0.2586 | 0.7343 | |
| GSE77861 | KLF8 | 11279 | 230986_at | -1.2345 | 0.0072 | |
| GSE97050 | KLF8 | 11279 | A_23_P217528 | -0.6261 | 0.1518 | |
| SRP007169 | KLF8 | 11279 | RNAseq | -1.2912 | 0.0156 | |
| SRP008496 | KLF8 | 11279 | RNAseq | -1.3746 | 0.0009 | |
| SRP064894 | KLF8 | 11279 | RNAseq | -1.9241 | 0.0000 | |
| SRP133303 | KLF8 | 11279 | RNAseq | -0.9562 | 0.0000 | |
| SRP159526 | KLF8 | 11279 | RNAseq | -2.0548 | 0.0000 | |
| SRP193095 | KLF8 | 11279 | RNAseq | -1.2632 | 0.0000 | |
| SRP219564 | KLF8 | 11279 | RNAseq | -1.9957 | 0.0008 | |
| TCGA | KLF8 | 11279 | RNAseq | 0.1123 | 0.5698 |
Upregulated datasets: 0; Downregulated datasets: 12.
Survival by KLF8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KLF8:
No record found for this gene.
Somatic mutations of KLF8:
Generating mutation plots.
Highly correlated genes for KLF8:
Showing top 20/1965 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KLF8 | SASH1 | 0.838895 | 11 | 0 | 11 |
| KLF8 | MPP7 | 0.835611 | 7 | 0 | 7 |
| KLF8 | SH3BGRL2 | 0.8159 | 7 | 0 | 7 |
| KLF8 | C5orf66-AS1 | 0.80867 | 6 | 0 | 6 |
| KLF8 | TRIP10 | 0.804226 | 11 | 0 | 11 |
| KLF8 | ENDOU | 0.801118 | 11 | 0 | 11 |
| KLF8 | RMND5B | 0.798309 | 11 | 0 | 11 |
| KLF8 | CYP2J2 | 0.798259 | 10 | 0 | 10 |
| KLF8 | SORT1 | 0.797345 | 11 | 0 | 11 |
| KLF8 | CAPN14 | 0.797331 | 6 | 0 | 6 |
| KLF8 | CAPNS2 | 0.797259 | 5 | 0 | 5 |
| KLF8 | SLC16A6 | 0.796499 | 11 | 0 | 11 |
| KLF8 | PADI1 | 0.796371 | 8 | 0 | 8 |
| KLF8 | PRSS27 | 0.796233 | 6 | 0 | 6 |
| KLF8 | RANBP9 | 0.795112 | 11 | 0 | 11 |
| KLF8 | SIM2 | 0.793414 | 11 | 0 | 11 |
| KLF8 | SLURP1 | 0.792526 | 10 | 0 | 10 |
| KLF8 | C18orf25 | 0.792363 | 11 | 0 | 11 |
| KLF8 | KRT78 | 0.79122 | 7 | 0 | 7 |
| KLF8 | EHD3 | 0.790867 | 11 | 0 | 11 |
For details and further investigation, click here
