| Full name: kelch like family member 11 | Alias Symbol: FLJ10572 | ||
| Type: protein-coding gene | Cytoband: 17q21.2 | ||
| Entrez ID: 55175 | HGNC ID: HGNC:19008 | Ensembl Gene: ENSG00000178502 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of KLHL11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KLHL11 | 55175 | 220657_at | -0.0756 | 0.8181 | |
| GSE20347 | KLHL11 | 55175 | 220657_at | 0.2096 | 0.0009 | |
| GSE23400 | KLHL11 | 55175 | 220657_at | -0.0563 | 0.1459 | |
| GSE26886 | KLHL11 | 55175 | 220657_at | 0.2516 | 0.0346 | |
| GSE29001 | KLHL11 | 55175 | 220657_at | -0.0244 | 0.8745 | |
| GSE38129 | KLHL11 | 55175 | 220657_at | 0.1455 | 0.0824 | |
| GSE45670 | KLHL11 | 55175 | 220657_at | 0.1984 | 0.0206 | |
| GSE53622 | KLHL11 | 55175 | 153029 | 0.3966 | 0.0000 | |
| GSE53624 | KLHL11 | 55175 | 153029 | 0.6297 | 0.0000 | |
| GSE63941 | KLHL11 | 55175 | 220657_at | 0.7593 | 0.0105 | |
| GSE77861 | KLHL11 | 55175 | 220657_at | -0.0170 | 0.8619 | |
| GSE97050 | KLHL11 | 55175 | A_23_P55388 | 0.3634 | 0.3276 | |
| SRP007169 | KLHL11 | 55175 | RNAseq | 0.8678 | 0.0164 | |
| SRP008496 | KLHL11 | 55175 | RNAseq | 0.7256 | 0.0004 | |
| SRP064894 | KLHL11 | 55175 | RNAseq | 0.1972 | 0.1682 | |
| SRP133303 | KLHL11 | 55175 | RNAseq | 0.4436 | 0.0001 | |
| SRP159526 | KLHL11 | 55175 | RNAseq | 0.6710 | 0.0088 | |
| SRP193095 | KLHL11 | 55175 | RNAseq | 0.3203 | 0.0004 | |
| SRP219564 | KLHL11 | 55175 | RNAseq | 0.2511 | 0.3551 | |
| TCGA | KLHL11 | 55175 | RNAseq | 0.0183 | 0.8461 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KLHL11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KLHL11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KLHL11 | 55175 | 6 | 2 | 22 | |
| GSE20123 | KLHL11 | 55175 | 6 | 2 | 22 | |
| GSE43470 | KLHL11 | 55175 | 1 | 2 | 40 | |
| GSE46452 | KLHL11 | 55175 | 34 | 0 | 25 | |
| GSE47630 | KLHL11 | 55175 | 8 | 1 | 31 | |
| GSE54993 | KLHL11 | 55175 | 3 | 4 | 63 | |
| GSE54994 | KLHL11 | 55175 | 8 | 5 | 40 | |
| GSE60625 | KLHL11 | 55175 | 4 | 0 | 7 | |
| GSE74703 | KLHL11 | 55175 | 1 | 1 | 34 | |
| GSE74704 | KLHL11 | 55175 | 4 | 1 | 15 | |
| TCGA | KLHL11 | 55175 | 22 | 7 | 67 |
Total number of gains: 97; Total number of losses: 25; Total Number of normals: 366.
Somatic mutations of KLHL11:
Generating mutation plots.
Highly correlated genes for KLHL11:
Showing top 20/528 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KLHL11 | CISD3 | 0.777094 | 3 | 0 | 3 |
| KLHL11 | FAM199X | 0.758865 | 3 | 0 | 3 |
| KLHL11 | DNAJC19 | 0.756873 | 3 | 0 | 3 |
| KLHL11 | EARS2 | 0.744527 | 3 | 0 | 3 |
| KLHL11 | PMS2 | 0.743418 | 3 | 0 | 3 |
| KLHL11 | OR7E24 | 0.742111 | 3 | 0 | 3 |
| KLHL11 | ANAPC1 | 0.732054 | 3 | 0 | 3 |
| KLHL11 | ZSCAN20 | 0.731497 | 3 | 0 | 3 |
| KLHL11 | CDYL2 | 0.729313 | 3 | 0 | 3 |
| KLHL11 | C15orf61 | 0.726735 | 3 | 0 | 3 |
| KLHL11 | QTRT1 | 0.725613 | 3 | 0 | 3 |
| KLHL11 | C3orf33 | 0.725044 | 3 | 0 | 3 |
| KLHL11 | TTBK2 | 0.724853 | 3 | 0 | 3 |
| KLHL11 | PIP4K2B | 0.722132 | 3 | 0 | 3 |
| KLHL11 | MED30 | 0.716386 | 3 | 0 | 3 |
| KLHL11 | CHCHD5 | 0.713689 | 3 | 0 | 3 |
| KLHL11 | ADPRH | 0.70488 | 6 | 0 | 6 |
| KLHL11 | ZC3HC1 | 0.704391 | 3 | 0 | 3 |
| KLHL11 | GZF1 | 0.703075 | 3 | 0 | 3 |
| KLHL11 | PTBP1 | 0.702856 | 4 | 0 | 4 |
For details and further investigation, click here
