| Full name: eukaryotic translation initiation factor 5 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q32.32 | ||
| Entrez ID: 1983 | HGNC ID: HGNC:3299 | Ensembl Gene: ENSG00000100664 | OMIM ID: 601710 |
| Drug and gene relationship at DGIdb | |||
Expression of EIF5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EIF5 | 1983 | 208705_s_at | -0.0146 | 0.9798 | |
| GSE20347 | EIF5 | 1983 | 208705_s_at | 0.0404 | 0.7733 | |
| GSE23400 | EIF5 | 1983 | 208705_s_at | 0.0889 | 0.3355 | |
| GSE26886 | EIF5 | 1983 | 208708_x_at | -0.4365 | 0.1903 | |
| GSE29001 | EIF5 | 1983 | 208706_s_at | -0.0362 | 0.9110 | |
| GSE38129 | EIF5 | 1983 | 208705_s_at | 0.1358 | 0.1901 | |
| GSE45670 | EIF5 | 1983 | 208705_s_at | 0.1851 | 0.2748 | |
| GSE53622 | EIF5 | 1983 | 16913 | -0.2214 | 0.0465 | |
| GSE53624 | EIF5 | 1983 | 16913 | -0.1914 | 0.0174 | |
| GSE63941 | EIF5 | 1983 | 208705_s_at | 1.0181 | 0.0093 | |
| GSE77861 | EIF5 | 1983 | 208705_s_at | 0.4145 | 0.2998 | |
| GSE97050 | EIF5 | 1983 | A_24_P398810 | -0.7039 | 0.1949 | |
| SRP007169 | EIF5 | 1983 | RNAseq | 0.0572 | 0.8584 | |
| SRP008496 | EIF5 | 1983 | RNAseq | 0.0469 | 0.8262 | |
| SRP064894 | EIF5 | 1983 | RNAseq | -0.0893 | 0.6355 | |
| SRP133303 | EIF5 | 1983 | RNAseq | 0.1403 | 0.4107 | |
| SRP159526 | EIF5 | 1983 | RNAseq | -0.0310 | 0.9220 | |
| SRP193095 | EIF5 | 1983 | RNAseq | -0.2110 | 0.0880 | |
| SRP219564 | EIF5 | 1983 | RNAseq | -0.4468 | 0.1024 | |
| TCGA | EIF5 | 1983 | RNAseq | -0.0282 | 0.4845 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by EIF5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EIF5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EIF5 | 1983 | 12 | 3 | 15 | |
| GSE20123 | EIF5 | 1983 | 11 | 2 | 17 | |
| GSE43470 | EIF5 | 1983 | 6 | 4 | 33 | |
| GSE46452 | EIF5 | 1983 | 18 | 4 | 37 | |
| GSE47630 | EIF5 | 1983 | 10 | 8 | 22 | |
| GSE54993 | EIF5 | 1983 | 3 | 8 | 59 | |
| GSE54994 | EIF5 | 1983 | 21 | 4 | 28 | |
| GSE60625 | EIF5 | 1983 | 0 | 2 | 9 | |
| GSE74703 | EIF5 | 1983 | 5 | 3 | 28 | |
| GSE74704 | EIF5 | 1983 | 5 | 2 | 13 | |
| TCGA | EIF5 | 1983 | 33 | 20 | 43 |
Total number of gains: 124; Total number of losses: 60; Total Number of normals: 304.
Somatic mutations of EIF5:
Generating mutation plots.
Highly correlated genes for EIF5:
Showing top 20/233 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EIF5 | FBXL4 | 0.783923 | 3 | 0 | 3 |
| EIF5 | NASP | 0.763888 | 3 | 0 | 3 |
| EIF5 | CCDC91 | 0.75402 | 3 | 0 | 3 |
| EIF5 | TANC1 | 0.741153 | 3 | 0 | 3 |
| EIF5 | CCNC | 0.740229 | 3 | 0 | 3 |
| EIF5 | ZNF280C | 0.735503 | 3 | 0 | 3 |
| EIF5 | TMEM205 | 0.733235 | 3 | 0 | 3 |
| EIF5 | KRR1 | 0.730717 | 3 | 0 | 3 |
| EIF5 | POLR3C | 0.71927 | 4 | 0 | 4 |
| EIF5 | PGGT1B | 0.717722 | 3 | 0 | 3 |
| EIF5 | ASB2 | 0.717614 | 3 | 0 | 3 |
| EIF5 | FEM1C | 0.715798 | 3 | 0 | 3 |
| EIF5 | INTS6 | 0.707776 | 3 | 0 | 3 |
| EIF5 | TPR | 0.706352 | 3 | 0 | 3 |
| EIF5 | MN1 | 0.70539 | 3 | 0 | 3 |
| EIF5 | ANAPC4 | 0.703789 | 3 | 0 | 3 |
| EIF5 | ZNF146 | 0.698865 | 3 | 0 | 3 |
| EIF5 | UEVLD | 0.697682 | 3 | 0 | 3 |
| EIF5 | METTL14 | 0.692829 | 3 | 0 | 3 |
| EIF5 | MTRF1 | 0.692297 | 3 | 0 | 3 |
For details and further investigation, click here
