| Full name: lysosomal associated membrane protein family member 5 | Alias Symbol: dJ1119D9.3|BAD-LAMP|UNC-46 | ||
| Type: protein-coding gene | Cytoband: 20p12.2 | ||
| Entrez ID: 24141 | HGNC ID: HGNC:16097 | Ensembl Gene: ENSG00000125869 | OMIM ID: 614641 |
| Drug and gene relationship at DGIdb | |||
Expression of LAMP5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LAMP5 | 24141 | 219463_at | 1.3308 | 0.0512 | |
| GSE20347 | LAMP5 | 24141 | 219463_at | 0.4618 | 0.0004 | |
| GSE23400 | LAMP5 | 24141 | 219463_at | 0.3338 | 0.0000 | |
| GSE26886 | LAMP5 | 24141 | 219463_at | 1.0769 | 0.0063 | |
| GSE29001 | LAMP5 | 24141 | 219463_at | 0.6672 | 0.0063 | |
| GSE38129 | LAMP5 | 24141 | 219463_at | 0.8616 | 0.0000 | |
| GSE45670 | LAMP5 | 24141 | 219463_at | 0.4208 | 0.1335 | |
| GSE53622 | LAMP5 | 24141 | 59268 | 2.2470 | 0.0000 | |
| GSE53624 | LAMP5 | 24141 | 59268 | 2.7698 | 0.0000 | |
| GSE63941 | LAMP5 | 24141 | 219463_at | -0.2342 | 0.1850 | |
| GSE77861 | LAMP5 | 24141 | 219463_at | -0.0087 | 0.9450 | |
| SRP133303 | LAMP5 | 24141 | RNAseq | 2.8446 | 0.0000 | |
| SRP159526 | LAMP5 | 24141 | RNAseq | 2.5316 | 0.0000 | |
| SRP219564 | LAMP5 | 24141 | RNAseq | 2.7975 | 0.0071 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by LAMP5 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of LAMP5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LAMP5 | 24141 | 9 | 1 | 20 | |
| GSE20123 | LAMP5 | 24141 | 9 | 1 | 20 | |
| GSE43470 | LAMP5 | 24141 | 11 | 1 | 31 | |
| GSE46452 | LAMP5 | 24141 | 26 | 1 | 32 | |
| GSE47630 | LAMP5 | 24141 | 18 | 4 | 18 | |
| GSE54993 | LAMP5 | 24141 | 1 | 14 | 55 | |
| GSE54994 | LAMP5 | 24141 | 25 | 1 | 27 | |
| GSE60625 | LAMP5 | 24141 | 0 | 0 | 11 | |
| GSE74703 | LAMP5 | 24141 | 8 | 1 | 27 | |
| GSE74704 | LAMP5 | 24141 | 4 | 1 | 15 | |
| TCGA | LAMP5 | 24141 | 42 | 10 | 44 |
Total number of gains: 153; Total number of losses: 35; Total Number of normals: 300.
Somatic mutations of LAMP5:
Generating mutation plots.
Highly correlated genes for LAMP5:
Showing top 20/527 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LAMP5 | IL4I1 | 0.694667 | 4 | 0 | 4 |
| LAMP5 | CMTM3 | 0.681998 | 6 | 0 | 6 |
| LAMP5 | LBX2-AS1 | 0.676675 | 4 | 0 | 4 |
| LAMP5 | FKBP7 | 0.674204 | 3 | 0 | 3 |
| LAMP5 | MMP11 | 0.668347 | 8 | 0 | 8 |
| LAMP5 | C1QTNF6 | 0.667251 | 5 | 0 | 5 |
| LAMP5 | CTHRC1 | 0.657477 | 6 | 0 | 4 |
| LAMP5 | NOX4 | 0.656848 | 10 | 0 | 9 |
| LAMP5 | NPFFR2 | 0.655922 | 3 | 0 | 3 |
| LAMP5 | ADAM12 | 0.654405 | 4 | 0 | 3 |
| LAMP5 | TMEM263 | 0.65371 | 4 | 0 | 4 |
| LAMP5 | COL5A1 | 0.653698 | 9 | 0 | 9 |
| LAMP5 | COL10A1 | 0.652761 | 9 | 0 | 9 |
| LAMP5 | PPP1R18 | 0.643631 | 4 | 0 | 3 |
| LAMP5 | LINC01116 | 0.643242 | 4 | 0 | 4 |
| LAMP5 | GPX8 | 0.641448 | 5 | 0 | 4 |
| LAMP5 | DNTTIP1 | 0.640698 | 4 | 0 | 4 |
| LAMP5 | PLA2G15 | 0.640155 | 4 | 0 | 3 |
| LAMP5 | HAPLN3 | 0.639795 | 3 | 0 | 3 |
| LAMP5 | XRN2 | 0.638531 | 5 | 0 | 4 |
For details and further investigation, click here
