| Full name: phospholipase A2 group XV | Alias Symbol: LLPL|GXVPLA2 | ||
| Type: protein-coding gene | Cytoband: 16q22.1 | ||
| Entrez ID: 23659 | HGNC ID: HGNC:17163 | Ensembl Gene: ENSG00000103066 | OMIM ID: 609362 |
| Drug and gene relationship at DGIdb | |||
Expression of PLA2G15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PLA2G15 | 23659 | 204458_at | 0.8420 | 0.0537 | |
| GSE20347 | PLA2G15 | 23659 | 204458_at | 0.7334 | 0.0000 | |
| GSE23400 | PLA2G15 | 23659 | 204458_at | 0.2779 | 0.0000 | |
| GSE26886 | PLA2G15 | 23659 | 204458_at | 1.0121 | 0.0000 | |
| GSE29001 | PLA2G15 | 23659 | 204458_at | 0.4830 | 0.0007 | |
| GSE38129 | PLA2G15 | 23659 | 204458_at | 0.7838 | 0.0000 | |
| GSE45670 | PLA2G15 | 23659 | 204458_at | 0.1912 | 0.1595 | |
| GSE53622 | PLA2G15 | 23659 | 6307 | -0.0378 | 0.7669 | |
| GSE53624 | PLA2G15 | 23659 | 6307 | 0.2264 | 0.0342 | |
| GSE63941 | PLA2G15 | 23659 | 204458_at | -1.1007 | 0.0141 | |
| GSE77861 | PLA2G15 | 23659 | 204458_at | 0.1476 | 0.3442 | |
| GSE97050 | PLA2G15 | 23659 | A_33_P3224745 | 0.4014 | 0.2651 | |
| SRP007169 | PLA2G15 | 23659 | RNAseq | 1.2275 | 0.0395 | |
| SRP008496 | PLA2G15 | 23659 | RNAseq | 1.0909 | 0.0065 | |
| SRP064894 | PLA2G15 | 23659 | RNAseq | 1.2647 | 0.0000 | |
| SRP133303 | PLA2G15 | 23659 | RNAseq | 0.9839 | 0.0000 | |
| SRP159526 | PLA2G15 | 23659 | RNAseq | 1.1620 | 0.0045 | |
| SRP193095 | PLA2G15 | 23659 | RNAseq | 0.8431 | 0.0000 | |
| SRP219564 | PLA2G15 | 23659 | RNAseq | 0.6834 | 0.1209 | |
| TCGA | PLA2G15 | 23659 | RNAseq | 0.1644 | 0.0098 |
Upregulated datasets: 5; Downregulated datasets: 1.
Survival by PLA2G15 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PLA2G15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PLA2G15 | 23659 | 9 | 2 | 19 | |
| GSE20123 | PLA2G15 | 23659 | 9 | 2 | 19 | |
| GSE43470 | PLA2G15 | 23659 | 1 | 9 | 33 | |
| GSE46452 | PLA2G15 | 23659 | 38 | 1 | 20 | |
| GSE47630 | PLA2G15 | 23659 | 11 | 8 | 21 | |
| GSE54993 | PLA2G15 | 23659 | 2 | 4 | 64 | |
| GSE54994 | PLA2G15 | 23659 | 8 | 10 | 35 | |
| GSE60625 | PLA2G15 | 23659 | 4 | 0 | 7 | |
| GSE74703 | PLA2G15 | 23659 | 1 | 6 | 29 | |
| GSE74704 | PLA2G15 | 23659 | 5 | 1 | 14 | |
| TCGA | PLA2G15 | 23659 | 31 | 12 | 53 |
Total number of gains: 119; Total number of losses: 55; Total Number of normals: 314.
Somatic mutations of PLA2G15:
Generating mutation plots.
Highly correlated genes for PLA2G15:
Showing top 20/672 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PLA2G15 | PBX4 | 0.747445 | 3 | 0 | 3 |
| PLA2G15 | C4orf46 | 0.74487 | 3 | 0 | 3 |
| PLA2G15 | PLBD2 | 0.734714 | 5 | 0 | 5 |
| PLA2G15 | ABCC10 | 0.725221 | 4 | 0 | 3 |
| PLA2G15 | SPATA17 | 0.71616 | 3 | 0 | 3 |
| PLA2G15 | MYBBP1A | 0.703214 | 5 | 0 | 3 |
| PLA2G15 | IFT43 | 0.699691 | 4 | 0 | 4 |
| PLA2G15 | SMIM3 | 0.699627 | 3 | 0 | 3 |
| PLA2G15 | DOCK2 | 0.697741 | 3 | 0 | 3 |
| PLA2G15 | MRGBP | 0.697693 | 7 | 0 | 7 |
| PLA2G15 | SNRPD2 | 0.694698 | 4 | 0 | 3 |
| PLA2G15 | PLAU | 0.688793 | 8 | 0 | 7 |
| PLA2G15 | HOMER3 | 0.688742 | 10 | 0 | 9 |
| PLA2G15 | YBX1 | 0.686768 | 5 | 0 | 5 |
| PLA2G15 | ZNF446 | 0.677878 | 3 | 0 | 3 |
| PLA2G15 | HSPE1 | 0.672213 | 4 | 0 | 4 |
| PLA2G15 | GNL2 | 0.66961 | 3 | 0 | 3 |
| PLA2G15 | SOAT1 | 0.666768 | 7 | 0 | 5 |
| PLA2G15 | RTEL1 | 0.66669 | 3 | 0 | 3 |
| PLA2G15 | ZNF133 | 0.665319 | 5 | 0 | 4 |
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