| Full name: interleukin 4 induced 1 | Alias Symbol: FIG1 | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 259307 | HGNC ID: HGNC:19094 | Ensembl Gene: ENSG00000104951 | OMIM ID: 609742 |
| Drug and gene relationship at DGIdb | |||
Expression of IL4I1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IL4I1 | 259307 | 230966_at | 0.8085 | 0.2594 | |
| GSE26886 | IL4I1 | 259307 | 230966_at | 0.7280 | 0.0023 | |
| GSE45670 | IL4I1 | 259307 | 230966_at | 0.2914 | 0.0985 | |
| GSE53622 | IL4I1 | 259307 | 53804 | 1.8695 | 0.0000 | |
| GSE53624 | IL4I1 | 259307 | 53804 | 1.9587 | 0.0000 | |
| GSE63941 | IL4I1 | 259307 | 230966_at | -0.0203 | 0.9201 | |
| GSE77861 | IL4I1 | 259307 | 230966_at | 0.0499 | 0.7040 | |
| GSE97050 | IL4I1 | 259307 | A_33_P3405424 | 1.2156 | 0.1657 | |
| SRP007169 | IL4I1 | 259307 | RNAseq | 3.9173 | 0.0003 | |
| SRP064894 | IL4I1 | 259307 | RNAseq | 2.9099 | 0.0000 | |
| SRP133303 | IL4I1 | 259307 | RNAseq | 2.1171 | 0.0000 | |
| SRP159526 | IL4I1 | 259307 | RNAseq | 2.3208 | 0.0112 | |
| SRP193095 | IL4I1 | 259307 | RNAseq | 1.6206 | 0.0000 | |
| SRP219564 | IL4I1 | 259307 | RNAseq | 2.7664 | 0.0001 | |
| TCGA | IL4I1 | 259307 | RNAseq | 0.8190 | 0.0000 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by IL4I1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IL4I1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IL4I1 | 259307 | 4 | 4 | 22 | |
| GSE20123 | IL4I1 | 259307 | 4 | 3 | 23 | |
| GSE43470 | IL4I1 | 259307 | 5 | 11 | 27 | |
| GSE46452 | IL4I1 | 259307 | 45 | 1 | 13 | |
| GSE47630 | IL4I1 | 259307 | 10 | 6 | 24 | |
| GSE54993 | IL4I1 | 259307 | 17 | 4 | 49 | |
| GSE54994 | IL4I1 | 259307 | 4 | 14 | 35 | |
| GSE60625 | IL4I1 | 259307 | 9 | 0 | 2 | |
| GSE74703 | IL4I1 | 259307 | 5 | 7 | 24 | |
| GSE74704 | IL4I1 | 259307 | 4 | 1 | 15 | |
| TCGA | IL4I1 | 259307 | 14 | 18 | 64 |
Total number of gains: 121; Total number of losses: 69; Total Number of normals: 298.
Somatic mutations of IL4I1:
Generating mutation plots.
Highly correlated genes for IL4I1:
Showing top 20/1070 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IL4I1 | ST20 | 0.788206 | 3 | 0 | 3 |
| IL4I1 | LAIR1 | 0.765375 | 4 | 0 | 4 |
| IL4I1 | LOX | 0.740867 | 3 | 0 | 3 |
| IL4I1 | USP41 | 0.739987 | 3 | 0 | 3 |
| IL4I1 | LILRB1 | 0.737944 | 5 | 0 | 5 |
| IL4I1 | EPYC | 0.736329 | 3 | 0 | 3 |
| IL4I1 | PLA2G7 | 0.729014 | 8 | 0 | 7 |
| IL4I1 | APOC1 | 0.718511 | 7 | 0 | 7 |
| IL4I1 | PDIA5 | 0.707537 | 3 | 0 | 3 |
| IL4I1 | SIGLEC12 | 0.707518 | 3 | 0 | 3 |
| IL4I1 | RAC3 | 0.702729 | 3 | 0 | 3 |
| IL4I1 | CTHRC1 | 0.699509 | 6 | 0 | 5 |
| IL4I1 | MMP12 | 0.696685 | 7 | 0 | 6 |
| IL4I1 | SLC7A7 | 0.69541 | 7 | 0 | 7 |
| IL4I1 | LAMP5 | 0.694667 | 4 | 0 | 4 |
| IL4I1 | TFEC | 0.693639 | 6 | 0 | 5 |
| IL4I1 | MMP11 | 0.693323 | 5 | 0 | 5 |
| IL4I1 | MARCKSL1 | 0.689232 | 7 | 0 | 6 |
| IL4I1 | APOE | 0.688166 | 8 | 0 | 7 |
| IL4I1 | MDK | 0.687344 | 7 | 0 | 5 |
For details and further investigation, click here
