CMTM3

 

Full name: CKLF like MARVEL transmembrane domain containing 3 Alias Symbol: FLJ31762|BNAS2
Type: protein-coding gene Cytoband: 16q22.1
Entrez ID: 123920 HGNC ID: HGNC:19174 Ensembl Gene: ENSG00000140931 OMIM ID: 607886
Drug and gene relationship at DGIdb

 

Expression of CMTM3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CMTM3 123920 224733_at 0.4751 0.2758
GSE26886 CMTM3 123920 224733_at 1.1222 0.0000
GSE45670 CMTM3 123920 224733_at -0.0919 0.7824
GSE53622 CMTM3 123920 18930 1.2305 0.0000
GSE53624 CMTM3 123920 18930 1.4453 0.0000
GSE63941 CMTM3 123920 224733_at -2.5165 0.0630
GSE77861 CMTM3 123920 224733_at 0.1991 0.2852
GSE97050 CMTM3 123920 A_23_P88865 0.6880 0.0888
SRP007169 CMTM3 123920 RNAseq 2.5709 0.0003
SRP008496 CMTM3 123920 RNAseq 2.0625 0.0000
SRP064894 CMTM3 123920 RNAseq 1.4501 0.0000
SRP133303 CMTM3 123920 RNAseq 1.2789 0.0000
SRP159526 CMTM3 123920 RNAseq 1.3040 0.0126
SRP193095 CMTM3 123920 RNAseq 1.1109 0.0000
SRP219564 CMTM3 123920 RNAseq 0.9939 0.0093
TCGA CMTM3 123920 RNAseq 0.4184 0.0001

Upregulated datasets: 9; Downregulated datasets: 0.  

 

Survival by CMTM3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CMTM3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CMTM3 123920 8 2 20
GSE20123 CMTM3 123920 8 2 20
GSE43470 CMTM3 123920 1 8 34
GSE46452 CMTM3 123920 38 1 20
GSE47630 CMTM3 123920 10 8 22
GSE54993 CMTM3 123920 2 4 64
GSE54994 CMTM3 123920 8 10 35
GSE60625 CMTM3 123920 4 0 7
GSE74703 CMTM3 123920 1 5 30
GSE74704 CMTM3 123920 5 1 14
TCGA CMTM3 123920 30 11 55

Total number of gains: 115; Total number of losses: 52; Total Number of normals: 321.  

 

Somatic mutations of CMTM3:

 

Generating mutation plots.

 

Highly correlated genes for CMTM3:

 

Showing top 20/1253 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CMTM3PLXNC10.77848606
CMTM3FCGR3A0.776686303
CMTM3CDH110.758932909
CMTM3VCAN0.752523908
CMTM3RUNX20.751529605
CMTM3LRRC8C0.750088303
CMTM3COL6A30.747828909
CMTM3COL8A10.745757909
CMTM3MFAP20.745349808
CMTM3APOC10.742599505
CMTM3COL5A10.740544907
CMTM3SPON20.738143404
CMTM3THY10.738024908
CMTM3GALNT100.737412707
CMTM3FCGR2A0.735698706
CMTM3COL5A20.72782908
CMTM3PCOLCE0.72693907
CMTM3PLXND10.723622808
CMTM3LOXL20.72241707
CMTM3FMNL30.720508706

For details and further investigation, click here