| Full name: LARGE antisense RNA 1 | Alias Symbol: | ||
| Type: non-coding RNA | Cytoband: 22q12.3 | ||
| Entrez ID: 100506195 | HGNC ID: HGNC:40336 | Ensembl Gene: ENSG00000224973 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LARGE-AS1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LARGE-AS1 | 100506195 | 1562449_s_at | -0.1205 | 0.6041 | |
| GSE26886 | LARGE-AS1 | 100506195 | 1562449_s_at | -0.1724 | 0.0957 | |
| GSE45670 | LARGE-AS1 | 100506195 | 1562449_s_at | 0.1048 | 0.1900 | |
| GSE53622 | LARGE-AS1 | 100506195 | 24658 | 0.0503 | 0.6542 | |
| GSE53624 | LARGE-AS1 | 100506195 | 24658 | 0.0787 | 0.3766 | |
| GSE63941 | LARGE-AS1 | 100506195 | 1562449_s_at | -0.0920 | 0.5665 | |
| GSE77861 | LARGE-AS1 | 100506195 | 1562449_s_at | -0.0952 | 0.3422 | |
| SRP133303 | LARGE-AS1 | 100506195 | RNAseq | 0.0024 | 0.9947 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LARGE-AS1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of LARGE-AS1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LARGE-AS1 | 100506195 | 4 | 5 | 21 | |
| GSE20123 | LARGE-AS1 | 100506195 | 3 | 4 | 23 | |
| GSE43470 | LARGE-AS1 | 100506195 | 4 | 5 | 34 | |
| GSE46452 | LARGE-AS1 | 100506195 | 31 | 1 | 27 | |
| GSE47630 | LARGE-AS1 | 100506195 | 8 | 5 | 27 | |
| GSE54993 | LARGE-AS1 | 100506195 | 3 | 6 | 61 | |
| GSE54994 | LARGE-AS1 | 100506195 | 9 | 9 | 35 | |
| GSE60625 | LARGE-AS1 | 100506195 | 5 | 0 | 6 | |
| GSE74703 | LARGE-AS1 | 100506195 | 4 | 5 | 27 | |
| GSE74704 | LARGE-AS1 | 100506195 | 1 | 1 | 18 |
Total number of gains: 72; Total number of losses: 41; Total Number of normals: 279.
Somatic mutations of LARGE-AS1:
Generating mutation plots.
Highly correlated genes for LARGE-AS1:
Showing top 20/55 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LARGE-AS1 | KLHL10 | 0.72119 | 3 | 0 | 3 |
| LARGE-AS1 | MTUS2 | 0.709843 | 3 | 0 | 3 |
| LARGE-AS1 | LINC00470 | 0.642686 | 3 | 0 | 3 |
| LARGE-AS1 | KEL | 0.6389 | 3 | 0 | 3 |
| LARGE-AS1 | OR4D1 | 0.626111 | 3 | 0 | 3 |
| LARGE-AS1 | OCM2 | 0.621402 | 3 | 0 | 3 |
| LARGE-AS1 | C20orf202 | 0.615572 | 3 | 0 | 3 |
| LARGE-AS1 | MOB2 | 0.613707 | 3 | 0 | 3 |
| LARGE-AS1 | CTNNA2 | 0.610633 | 3 | 0 | 3 |
| LARGE-AS1 | TSSK3 | 0.608946 | 4 | 0 | 4 |
| LARGE-AS1 | CCDC13 | 0.606107 | 3 | 0 | 3 |
| LARGE-AS1 | TMEM114 | 0.604585 | 3 | 0 | 3 |
| LARGE-AS1 | PCA3 | 0.600042 | 4 | 0 | 3 |
| LARGE-AS1 | CPA1 | 0.599601 | 3 | 0 | 3 |
| LARGE-AS1 | LILRA2 | 0.588136 | 4 | 0 | 3 |
| LARGE-AS1 | KIF25 | 0.585313 | 4 | 0 | 4 |
| LARGE-AS1 | CXCR1 | 0.579768 | 3 | 0 | 3 |
| LARGE-AS1 | KCNA5 | 0.573383 | 3 | 0 | 3 |
| LARGE-AS1 | IQCJ-SCHIP1-AS1 | 0.571443 | 3 | 0 | 3 |
| LARGE-AS1 | FRMPD4 | 0.56864 | 4 | 0 | 3 |
For details and further investigation, click here
