| Full name: potassium voltage-gated channel subfamily A member 5 | Alias Symbol: Kv1.5|HK2|HPCN1 | ||
| Type: protein-coding gene | Cytoband: 12p13.32 | ||
| Entrez ID: 3741 | HGNC ID: HGNC:6224 | Ensembl Gene: ENSG00000130037 | OMIM ID: 176267 |
| Drug and gene relationship at DGIdb | |||
Expression of KCNA5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KCNA5 | 3741 | 206762_at | -1.6660 | 0.0535 | |
| GSE20347 | KCNA5 | 3741 | 206762_at | -0.0774 | 0.5362 | |
| GSE23400 | KCNA5 | 3741 | 206762_at | -0.4326 | 0.0000 | |
| GSE26886 | KCNA5 | 3741 | 206762_at | -0.1063 | 0.5600 | |
| GSE29001 | KCNA5 | 3741 | 206762_at | -0.1954 | 0.3159 | |
| GSE38129 | KCNA5 | 3741 | 206762_at | -0.6674 | 0.0000 | |
| GSE45670 | KCNA5 | 3741 | 206762_at | -0.7438 | 0.0000 | |
| GSE53622 | KCNA5 | 3741 | 153007 | -2.3767 | 0.0000 | |
| GSE53624 | KCNA5 | 3741 | 153007 | -2.4958 | 0.0000 | |
| GSE63941 | KCNA5 | 3741 | 206762_at | -0.0974 | 0.5493 | |
| GSE77861 | KCNA5 | 3741 | 206762_at | -0.1617 | 0.0905 | |
| GSE97050 | KCNA5 | 3741 | A_23_P417173 | -0.7401 | 0.3439 | |
| SRP064894 | KCNA5 | 3741 | RNAseq | -3.2848 | 0.0000 | |
| SRP133303 | KCNA5 | 3741 | RNAseq | -2.7603 | 0.0000 | |
| SRP159526 | KCNA5 | 3741 | RNAseq | -4.0929 | 0.0000 | |
| SRP219564 | KCNA5 | 3741 | RNAseq | -2.6237 | 0.0165 | |
| TCGA | KCNA5 | 3741 | RNAseq | -2.6623 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by KCNA5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KCNA5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KCNA5 | 3741 | 6 | 4 | 20 | |
| GSE20123 | KCNA5 | 3741 | 6 | 4 | 20 | |
| GSE43470 | KCNA5 | 3741 | 9 | 3 | 31 | |
| GSE46452 | KCNA5 | 3741 | 10 | 1 | 48 | |
| GSE47630 | KCNA5 | 3741 | 12 | 2 | 26 | |
| GSE54993 | KCNA5 | 3741 | 1 | 10 | 59 | |
| GSE54994 | KCNA5 | 3741 | 10 | 2 | 41 | |
| GSE60625 | KCNA5 | 3741 | 0 | 1 | 10 | |
| GSE74703 | KCNA5 | 3741 | 8 | 2 | 26 | |
| GSE74704 | KCNA5 | 3741 | 4 | 2 | 14 | |
| TCGA | KCNA5 | 3741 | 40 | 6 | 50 |
Total number of gains: 106; Total number of losses: 37; Total Number of normals: 345.
Somatic mutations of KCNA5:
Generating mutation plots.
Highly correlated genes for KCNA5:
Showing top 20/1219 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KCNA5 | ANGPTL1 | 0.836296 | 4 | 0 | 4 |
| KCNA5 | RAB9B | 0.810538 | 4 | 0 | 4 |
| KCNA5 | LINC01082 | 0.800715 | 4 | 0 | 4 |
| KCNA5 | SLMAP | 0.791365 | 4 | 0 | 4 |
| KCNA5 | FENDRR | 0.759521 | 4 | 0 | 4 |
| KCNA5 | MRVI1 | 0.742313 | 4 | 0 | 4 |
| KCNA5 | EIF4E3 | 0.726162 | 5 | 0 | 5 |
| KCNA5 | ZBTB47 | 0.724993 | 3 | 0 | 3 |
| KCNA5 | MACROD2 | 0.722458 | 3 | 0 | 3 |
| KCNA5 | RSPO1 | 0.721131 | 4 | 0 | 4 |
| KCNA5 | LRFN5 | 0.720732 | 3 | 0 | 3 |
| KCNA5 | ABCA8 | 0.719886 | 6 | 0 | 6 |
| KCNA5 | RBPMS2 | 0.719768 | 5 | 0 | 5 |
| KCNA5 | ZNF536 | 0.715692 | 9 | 0 | 9 |
| KCNA5 | SLITRK3 | 0.710457 | 9 | 0 | 8 |
| KCNA5 | ADAMTS8 | 0.710017 | 8 | 0 | 8 |
| KCNA5 | PRR26 | 0.709352 | 4 | 0 | 4 |
| KCNA5 | HSPB6 | 0.704583 | 9 | 0 | 9 |
| KCNA5 | MAMDC2 | 0.702919 | 5 | 0 | 4 |
| KCNA5 | CCL14 | 0.699792 | 3 | 0 | 3 |
For details and further investigation, click here
