| Full name: family with sequence similarity 220 member A | Alias Symbol: SIPAR|MGC12966|ACPIN1 | ||
| Type: protein-coding gene | Cytoband: 7p22.1 | ||
| Entrez ID: 84792 | HGNC ID: HGNC:22422 | Ensembl Gene: ENSG00000178397 | OMIM ID: 616628 |
| Drug and gene relationship at DGIdb | |||
Expression of FAM220A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM220A | 84792 | 224452_s_at | 0.1151 | 0.8292 | |
| GSE26886 | FAM220A | 84792 | 224452_s_at | 0.6865 | 0.0050 | |
| GSE45670 | FAM220A | 84792 | 224452_s_at | 0.5092 | 0.0001 | |
| GSE53622 | FAM220A | 84792 | 130206 | 0.6233 | 0.0000 | |
| GSE53624 | FAM220A | 84792 | 130206 | 0.3337 | 0.0000 | |
| GSE63941 | FAM220A | 84792 | 224452_s_at | 0.8960 | 0.0185 | |
| GSE77861 | FAM220A | 84792 | 224452_s_at | 0.6630 | 0.0014 | |
| SRP007169 | FAM220A | 84792 | RNAseq | -0.8145 | 0.0105 | |
| SRP008496 | FAM220A | 84792 | RNAseq | -0.0743 | 0.7815 | |
| SRP064894 | FAM220A | 84792 | RNAseq | 0.0708 | 0.6777 | |
| SRP133303 | FAM220A | 84792 | RNAseq | 0.6219 | 0.0006 | |
| SRP159526 | FAM220A | 84792 | RNAseq | 0.8828 | 0.0566 | |
| SRP193095 | FAM220A | 84792 | RNAseq | -0.1305 | 0.4424 | |
| SRP219564 | FAM220A | 84792 | RNAseq | -0.1545 | 0.5833 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FAM220A expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of FAM220A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM220A | 84792 | 14 | 1 | 15 | |
| GSE20123 | FAM220A | 84792 | 14 | 1 | 15 | |
| GSE43470 | FAM220A | 84792 | 6 | 1 | 36 | |
| GSE46452 | FAM220A | 84792 | 13 | 1 | 45 | |
| GSE47630 | FAM220A | 84792 | 9 | 1 | 30 | |
| GSE54993 | FAM220A | 84792 | 0 | 6 | 64 | |
| GSE54994 | FAM220A | 84792 | 20 | 1 | 32 | |
| GSE60625 | FAM220A | 84792 | 0 | 0 | 11 | |
| GSE74703 | FAM220A | 84792 | 6 | 0 | 30 | |
| GSE74704 | FAM220A | 84792 | 9 | 0 | 11 | |
| TCGA | FAM220A | 84792 | 55 | 5 | 36 |
Total number of gains: 146; Total number of losses: 17; Total Number of normals: 325.
Somatic mutations of FAM220A:
Generating mutation plots.
Highly correlated genes for FAM220A:
Showing top 20/424 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM220A | SPAST | 0.789129 | 3 | 0 | 3 |
| FAM220A | AIMP2 | 0.730699 | 5 | 0 | 5 |
| FAM220A | LEPROTL1 | 0.728665 | 3 | 0 | 3 |
| FAM220A | DENND4A | 0.712877 | 3 | 0 | 3 |
| FAM220A | PSMD4 | 0.703803 | 3 | 0 | 3 |
| FAM220A | FAF2 | 0.683113 | 3 | 0 | 3 |
| FAM220A | KIAA0895 | 0.682002 | 3 | 0 | 3 |
| FAM220A | MEF2A | 0.679386 | 4 | 0 | 3 |
| FAM220A | NME1 | 0.672906 | 3 | 0 | 3 |
| FAM220A | BLOC1S6 | 0.662308 | 3 | 0 | 3 |
| FAM220A | ABCA12 | 0.661726 | 4 | 0 | 4 |
| FAM220A | PDPR | 0.659304 | 3 | 0 | 3 |
| FAM220A | ASXL2 | 0.657959 | 4 | 0 | 4 |
| FAM220A | KCNK1 | 0.654512 | 4 | 0 | 3 |
| FAM220A | FEN1 | 0.654435 | 3 | 0 | 3 |
| FAM220A | TRMT61B | 0.652205 | 3 | 0 | 3 |
| FAM220A | FOXE1 | 0.651465 | 5 | 0 | 5 |
| FAM220A | DUSP18 | 0.650986 | 3 | 0 | 3 |
| FAM220A | STK3 | 0.648079 | 4 | 0 | 4 |
| FAM220A | PSMD2 | 0.646282 | 6 | 0 | 5 |
For details and further investigation, click here
