| Full name: leukocyte immunoglobulin like receptor A1 | Alias Symbol: LIR-6|CD85i|LIR6 | ||
| Type: protein-coding gene | Cytoband: 19q13.42 | ||
| Entrez ID: 11024 | HGNC ID: HGNC:6602 | Ensembl Gene: ENSG00000104974 | OMIM ID: 604810 |
| Drug and gene relationship at DGIdb | |||
LILRA1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04380 | Osteoclast differentiation |
Expression of LILRA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LILRA1 | 11024 | 210660_at | 0.0959 | 0.6098 | |
| GSE20347 | LILRA1 | 11024 | 207872_s_at | 0.0172 | 0.7644 | |
| GSE23400 | LILRA1 | 11024 | 210660_at | -0.0733 | 0.0098 | |
| GSE26886 | LILRA1 | 11024 | 207872_s_at | 0.1309 | 0.2543 | |
| GSE29001 | LILRA1 | 11024 | 210660_at | -0.0560 | 0.6562 | |
| GSE38129 | LILRA1 | 11024 | 207872_s_at | -0.0354 | 0.5141 | |
| GSE45670 | LILRA1 | 11024 | 210660_at | 0.0573 | 0.5163 | |
| GSE53622 | LILRA1 | 11024 | 25467 | -0.1132 | 0.3558 | |
| GSE53624 | LILRA1 | 11024 | 25467 | -0.0846 | 0.2808 | |
| GSE63941 | LILRA1 | 11024 | 207872_s_at | -0.0338 | 0.8492 | |
| GSE77861 | LILRA1 | 11024 | 207872_s_at | -0.0434 | 0.7947 | |
| GSE97050 | LILRA1 | 11024 | A_24_P348989 | 0.1940 | 0.3602 | |
| SRP133303 | LILRA1 | 11024 | RNAseq | 0.3703 | 0.1068 | |
| SRP159526 | LILRA1 | 11024 | RNAseq | 0.2986 | 0.7419 | |
| TCGA | LILRA1 | 11024 | RNAseq | 0.2207 | 0.6601 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LILRA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LILRA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LILRA1 | 11024 | 3 | 4 | 23 | |
| GSE20123 | LILRA1 | 11024 | 3 | 3 | 24 | |
| GSE43470 | LILRA1 | 11024 | 2 | 11 | 30 | |
| GSE46452 | LILRA1 | 11024 | 45 | 1 | 13 | |
| GSE47630 | LILRA1 | 11024 | 8 | 6 | 26 | |
| GSE54993 | LILRA1 | 11024 | 17 | 4 | 49 | |
| GSE54994 | LILRA1 | 11024 | 4 | 13 | 36 | |
| GSE60625 | LILRA1 | 11024 | 9 | 0 | 2 | |
| GSE74703 | LILRA1 | 11024 | 2 | 7 | 27 | |
| GSE74704 | LILRA1 | 11024 | 3 | 1 | 16 | |
| TCGA | LILRA1 | 11024 | 19 | 14 | 63 |
Total number of gains: 115; Total number of losses: 64; Total Number of normals: 309.
Somatic mutations of LILRA1:
Generating mutation plots.
Highly correlated genes for LILRA1:
Showing top 20/389 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LILRA1 | KIRREL2 | 0.74071 | 3 | 0 | 3 |
| LILRA1 | RALYL | 0.737823 | 3 | 0 | 3 |
| LILRA1 | PRKAR1B | 0.729384 | 3 | 0 | 3 |
| LILRA1 | DRG2 | 0.71206 | 3 | 0 | 3 |
| LILRA1 | ARHGAP30 | 0.706209 | 3 | 0 | 3 |
| LILRA1 | OR2H2 | 0.703989 | 4 | 0 | 4 |
| LILRA1 | SUN5 | 0.700308 | 3 | 0 | 3 |
| LILRA1 | HOXB6 | 0.698093 | 3 | 0 | 3 |
| LILRA1 | DAB1 | 0.69694 | 4 | 0 | 4 |
| LILRA1 | FOXB1 | 0.686403 | 4 | 0 | 3 |
| LILRA1 | PRF1 | 0.68576 | 4 | 0 | 4 |
| LILRA1 | ADORA3 | 0.681341 | 3 | 0 | 3 |
| LILRA1 | DIO3 | 0.67395 | 4 | 0 | 4 |
| LILRA1 | OR2J2 | 0.672702 | 3 | 0 | 3 |
| LILRA1 | CHRD | 0.672 | 4 | 0 | 3 |
| LILRA1 | AICDA | 0.667992 | 4 | 0 | 4 |
| LILRA1 | SPRED3 | 0.667984 | 3 | 0 | 3 |
| LILRA1 | RHAG | 0.661382 | 3 | 0 | 3 |
| LILRA1 | SLC6A18 | 0.660881 | 3 | 0 | 3 |
| LILRA1 | A1CF | 0.660003 | 4 | 0 | 3 |
For details and further investigation, click here
