| Full name: hydrogen voltage gated channel 1 | Alias Symbol: MGC15619|Hv1|VSOP | ||
| Type: protein-coding gene | Cytoband: 12q24.11 | ||
| Entrez ID: 84329 | HGNC ID: HGNC:28240 | Ensembl Gene: ENSG00000122986 | OMIM ID: 611227 |
| Drug and gene relationship at DGIdb | |||
Expression of HVCN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HVCN1 | 84329 | 226879_at | 0.0068 | 0.9908 | |
| GSE26886 | HVCN1 | 84329 | 226879_at | -0.1586 | 0.4729 | |
| GSE45670 | HVCN1 | 84329 | 226879_at | -0.0943 | 0.3706 | |
| GSE53622 | HVCN1 | 84329 | 99924 | 0.2802 | 0.0490 | |
| GSE53624 | HVCN1 | 84329 | 99924 | -0.0336 | 0.8553 | |
| GSE63941 | HVCN1 | 84329 | 226879_at | -0.2694 | 0.1840 | |
| GSE77861 | HVCN1 | 84329 | 226879_at | -0.0556 | 0.5953 | |
| GSE97050 | HVCN1 | 84329 | A_33_P3368014 | 0.4310 | 0.2417 | |
| SRP064894 | HVCN1 | 84329 | RNAseq | 0.4622 | 0.0449 | |
| SRP133303 | HVCN1 | 84329 | RNAseq | -0.1802 | 0.4696 | |
| SRP159526 | HVCN1 | 84329 | RNAseq | -0.3165 | 0.5132 | |
| SRP193095 | HVCN1 | 84329 | RNAseq | 0.2939 | 0.2785 | |
| SRP219564 | HVCN1 | 84329 | RNAseq | 0.1617 | 0.7049 | |
| TCGA | HVCN1 | 84329 | RNAseq | -0.0244 | 0.8756 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HVCN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HVCN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HVCN1 | 84329 | 5 | 3 | 22 | |
| GSE20123 | HVCN1 | 84329 | 5 | 3 | 22 | |
| GSE43470 | HVCN1 | 84329 | 2 | 1 | 40 | |
| GSE46452 | HVCN1 | 84329 | 9 | 1 | 49 | |
| GSE47630 | HVCN1 | 84329 | 9 | 3 | 28 | |
| GSE54993 | HVCN1 | 84329 | 0 | 5 | 65 | |
| GSE54994 | HVCN1 | 84329 | 5 | 2 | 46 | |
| GSE60625 | HVCN1 | 84329 | 0 | 0 | 11 | |
| GSE74703 | HVCN1 | 84329 | 2 | 0 | 34 | |
| GSE74704 | HVCN1 | 84329 | 2 | 2 | 16 | |
| TCGA | HVCN1 | 84329 | 22 | 11 | 63 |
Total number of gains: 61; Total number of losses: 31; Total Number of normals: 396.
Somatic mutations of HVCN1:
Generating mutation plots.
Highly correlated genes for HVCN1:
Showing top 20/443 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HVCN1 | KCNA3 | 0.792007 | 5 | 0 | 5 |
| HVCN1 | CERKL | 0.75996 | 3 | 0 | 3 |
| HVCN1 | HSD17B11 | 0.757781 | 3 | 0 | 3 |
| HVCN1 | CSF1R | 0.748909 | 6 | 0 | 6 |
| HVCN1 | HLA-DOA | 0.740914 | 4 | 0 | 4 |
| HVCN1 | PVRIG | 0.73963 | 4 | 0 | 3 |
| HVCN1 | MILR1 | 0.735014 | 5 | 0 | 5 |
| HVCN1 | ENTPD4 | 0.727337 | 3 | 0 | 3 |
| HVCN1 | TRMT5 | 0.724748 | 3 | 0 | 3 |
| HVCN1 | BIN2 | 0.722077 | 6 | 0 | 5 |
| HVCN1 | CYLD | 0.719389 | 3 | 0 | 3 |
| HVCN1 | DOK1 | 0.71809 | 4 | 0 | 4 |
| HVCN1 | RASGRP2 | 0.714586 | 4 | 0 | 4 |
| HVCN1 | MS4A6A | 0.711828 | 5 | 0 | 5 |
| HVCN1 | CACNA2D4 | 0.710923 | 3 | 0 | 3 |
| HVCN1 | NCKAP1L | 0.709113 | 5 | 0 | 4 |
| HVCN1 | LILRA2 | 0.706774 | 3 | 0 | 3 |
| HVCN1 | STK32B | 0.704588 | 4 | 0 | 4 |
| HVCN1 | RNF130 | 0.699656 | 4 | 0 | 4 |
| HVCN1 | TNFAIP8L2 | 0.699451 | 6 | 0 | 6 |
For details and further investigation, click here
