| Full name: syntaxin 11 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6q24.2 | ||
| Entrez ID: 8676 | HGNC ID: HGNC:11429 | Ensembl Gene: ENSG00000135604 | OMIM ID: 605014 |
| Drug and gene relationship at DGIdb | |||
Expression of STX11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STX11 | 8676 | 235670_at | -0.5070 | 0.5057 | |
| GSE20347 | STX11 | 8676 | 210190_at | -0.2885 | 0.0001 | |
| GSE23400 | STX11 | 8676 | 210190_at | -0.1050 | 0.0001 | |
| GSE26886 | STX11 | 8676 | 210190_at | 0.2441 | 0.1704 | |
| GSE29001 | STX11 | 8676 | 210190_at | -0.0733 | 0.5364 | |
| GSE38129 | STX11 | 8676 | 210190_at | -0.2182 | 0.0187 | |
| GSE45670 | STX11 | 8676 | 235670_at | -0.4243 | 0.0242 | |
| GSE53622 | STX11 | 8676 | 27760 | -0.5055 | 0.0001 | |
| GSE53624 | STX11 | 8676 | 27760 | -0.7523 | 0.0000 | |
| GSE63941 | STX11 | 8676 | 210190_at | 0.3107 | 0.3053 | |
| GSE77861 | STX11 | 8676 | 210190_at | -0.1453 | 0.4015 | |
| GSE97050 | STX11 | 8676 | A_23_P156788 | -0.1395 | 0.7799 | |
| SRP007169 | STX11 | 8676 | RNAseq | 0.0935 | 0.8920 | |
| SRP064894 | STX11 | 8676 | RNAseq | -0.5756 | 0.0199 | |
| SRP133303 | STX11 | 8676 | RNAseq | -0.2397 | 0.1378 | |
| SRP159526 | STX11 | 8676 | RNAseq | -0.7395 | 0.2231 | |
| SRP193095 | STX11 | 8676 | RNAseq | -0.0947 | 0.5256 | |
| SRP219564 | STX11 | 8676 | RNAseq | -0.2601 | 0.6600 | |
| TCGA | STX11 | 8676 | RNAseq | 0.2501 | 0.0887 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by STX11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STX11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STX11 | 8676 | 2 | 4 | 24 | |
| GSE20123 | STX11 | 8676 | 2 | 3 | 25 | |
| GSE43470 | STX11 | 8676 | 5 | 0 | 38 | |
| GSE46452 | STX11 | 8676 | 3 | 10 | 46 | |
| GSE47630 | STX11 | 8676 | 9 | 4 | 27 | |
| GSE54993 | STX11 | 8676 | 3 | 2 | 65 | |
| GSE54994 | STX11 | 8676 | 8 | 8 | 37 | |
| GSE60625 | STX11 | 8676 | 0 | 1 | 10 | |
| GSE74703 | STX11 | 8676 | 4 | 0 | 32 | |
| GSE74704 | STX11 | 8676 | 0 | 1 | 19 | |
| TCGA | STX11 | 8676 | 12 | 19 | 65 |
Total number of gains: 48; Total number of losses: 52; Total Number of normals: 388.
Somatic mutations of STX11:
Generating mutation plots.
Highly correlated genes for STX11:
Showing top 20/408 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STX11 | ZNF467 | 0.780099 | 3 | 0 | 3 |
| STX11 | HGF | 0.759612 | 3 | 0 | 3 |
| STX11 | HIC2 | 0.756052 | 3 | 0 | 3 |
| STX11 | DNAJB7 | 0.733084 | 3 | 0 | 3 |
| STX11 | CSTF2 | 0.731196 | 4 | 0 | 3 |
| STX11 | CMTR2 | 0.707773 | 3 | 0 | 3 |
| STX11 | C1orf122 | 0.706577 | 3 | 0 | 3 |
| STX11 | PAQR7 | 0.701709 | 3 | 0 | 3 |
| STX11 | PFDN5 | 0.700634 | 3 | 0 | 3 |
| STX11 | ANKRD37 | 0.697157 | 4 | 0 | 3 |
| STX11 | SNX14 | 0.694263 | 3 | 0 | 3 |
| STX11 | C9orf85 | 0.689825 | 3 | 0 | 3 |
| STX11 | LILRA2 | 0.688534 | 3 | 0 | 3 |
| STX11 | NAGLU | 0.685161 | 3 | 0 | 3 |
| STX11 | TIFA | 0.681723 | 4 | 0 | 3 |
| STX11 | DOK1 | 0.678777 | 4 | 0 | 3 |
| STX11 | PLK3 | 0.673055 | 4 | 0 | 4 |
| STX11 | TAL1 | 0.671677 | 3 | 0 | 3 |
| STX11 | POLR2A | 0.671299 | 3 | 0 | 3 |
| STX11 | CHRNE | 0.670599 | 4 | 0 | 4 |
For details and further investigation, click here
